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Hang Xiao PhD

TitleAssociate Professor
InstitutionUniversity of Massachusetts Amherst
DepartmentCollege of Natural Sciences
Address338 Chenoweth Laboratory
Amherst, MA 01003
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Du H, Han Y, Ma G, Tan C, Hu Q, Xiao H. Dietary intake of whole king oyster mushroom (Pleurotus eryngii) attenuated obesity via ameliorating lipid metabolism and alleviating gut microbiota dysbiosis. Food Res Int. 2024 May; 184:114228. PMID: 38609215.
    2. Qiu Z, Li L, Du H, Chen H, Chen G, Zheng Z, Xiao H. Physicochemical, Structural, and Functional Properties of Fructans from Single-Clove Garlic and Multiclove Garlic: A Comparison. J Agric Food Chem. 2024 Apr 10; 72(14):7818-7831. PMID: 38466922.
    3. Wu R, Prachyathipsakul T, Zhuang J, Liu H, Han Y, Liu B, Gong S, Qiu J, Wong S, Ribbe A, Medeiros J, Bhagabati J, Gao J, Wu P, Dutta R, Herrera R, Faraci S, Xiao H, Thayumanavan S. Conferring liver selectivity to a thyromimetic using a novel nanoparticle increases therapeutic efficacy in a diet-induced obesity animal model. PNAS Nexus. 2023 Aug; 2(8):pgad252. PMID: 37649581.
    4. Zhang J, Yang J, Duval C, Edin ML, Williams A, Lei L, Tu M, Pourmand E, Song R, Graves JP, DeGraff LM, Wong JJ, Wang Y, Sun Q, Sanidad KZ, Wong S, Han Y, Zhang Z, Lee KSS, Park Y, Xiao H, Liu Z, Decker EA, Cui W, Zeldin DC, Zhang G. CYP eicosanoid pathway mediates colon cancer-promoting effects of dietary linoleic acid. FASEB J. 2023 07; 37(7):e23009. PMID: 37273180.
      Citations:    Fields:    Translation:HumansAnimals
    5. Wu Y, Cao X, Du H, Guo X, Han Y, McClements DJ, Decker E, Xing B, Xiao H. Adverse effects of titanium dioxide nanoparticles on beneficial gut bacteria and host health based on untargeted metabolomics analysis. Environ Res. 2023 07 01; 228:115921. PMID: 37068726.
      Citations:    Fields:    Translation:HumansAnimalsCells
    6. Yi L, Wang Q, Luo H, Lei D, Tang Z, Lei S, Xiao H. Inhibitory Effects of Polyphenols-Rich Components From Three Edible Seaweeds on Inflammation and Colon Cancer in vitro. Front Nutr. 2022; 9:856273. PMID: 35634377.
    7. Li F, Han Y, Wu X, Cao X, Gao Z, Sun Y, Wang M, Xiao H. Gut Microbiota-Derived Resveratrol Metabolites, Dihydroresveratrol and Lunularin, Significantly Contribute to the Biological Activities of Resveratrol. Front Nutr. 2022; 9:912591. PMID: 35634412.
    8. Yi L, Wang Q, Luo H, Lei D, Tang Z, Lei S, Xiao H. Bioactive Components From Gracilaria rubra With Growth Inhibition on HCT116 Colon Cancer Cells and Anti-inflammatory Capacity in RAW 264.7 Macrophages. Front Nutr. 2022; 9:856282. PMID: 35464033.
    9. Zhang J, Walker ME, Sanidad KZ, Zhang H, Liang Y, Zhao E, Chacon-Vargas K, Yeliseyev V, Parsonnet J, Haggerty TD, Wang G, Simpson JB, Jariwala PB, Beaty VV, Yang J, Yang H, Panigrahy A, Minter LM, Kim D, Gibbons JG, Liu L, Li Z, Xiao H, Borlandelli V, Overkleeft HS, Cloer EW, Major MB, Goldfarb D, Cai Z, Redinbo MR, Zhang G. Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract. Nat Commun. 2022 01 10; 13(1):136. PMID: 35013263.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    10. Huang M, Han Y, Li L, Rakariyatham K, Wu X, Gao Z, Xiao H. Protective effects of non-extractable phenolics from strawberry against inflammation and colon cancer in vitro. Food Chem. 2022 Apr 16; 374:131759. PMID: 34896944.
      Citations: 5     Fields:    Translation:HumansAnimals
    11. Huang J, Lin B, Zhang Y, Xie Z, Zheng Y, Wang Q, Xiao H. Bamboo shavings derived O-acetylated xylan alleviates loperamide-induced constipation in mice. Carbohydr Polym. 2022 Jan 15; 276:118761. PMID: 34823784.
      Citations: 8     Fields:    Translation:AnimalsCells
    12. Luo H, Li Z, Straight CR, Wang Q, Zhou J, Sun Y, Lo CY, Yi L, Wu Y, Huang J, Wolfe W, Sutherland DZ, Miller MS, McClements DJ, Decker EA, Xiao H. Black pepper and vegetable oil-based emulsion synergistically enhance carotenoid bioavailability of raw vegetables in humans. Food Chem. 2022 Mar 30; 373(Pt B):131277. PMID: 34799132.
      Citations: 3     Fields:    Translation:HumansAnimals
    13. Sun Y, Wang Q, Wu X, Li F, Song M, Wang M, Cai X, Li Z, Gao Z, Zheng J, Qi C, Sun J, Xiao H. Gastrointestinal biotransformation and tissue distribution of pterostilbene after long-term dietary administration in mice. Food Chem. 2022 Mar 15; 372:131213. PMID: 34638060.
      Citations: 2     Fields:    Translation:Animals
    14. Luo H, Li Z, Yao M, McClements DJ, Xiao H. Impact of excipient emulsions made from different types of oils on the bioavailability and metabolism of curcumin in gastrointestinal tract. Food Chem. 2022 Feb 15; 370:130980. PMID: 34628238.
      Citations: 4     Fields:    Translation:HumansCells
    15. Yao M, Kitamura F, Han Y, Du H, Julian McClements D, Xiao H. Adverse effects of linoleic acid: Influence of lipid oxidation on lymphatic transport of citrus flavonoid and enterocyte morphology. Food Chem. 2022 Feb 01; 369:130968. PMID: 34479013.
      Citations:    Fields:    Translation:HumansAnimalsCells
    16. Ma G, Hu Q, Han Y, Du H, Yang W, Pan C, Cao X, Muinde Kimatu B, Pei F, Xiao H. Inhibitory effects of ?-type glycosidic polysaccharide from Pleurotus eryngii on dextran sodium sulfate-induced colitis in mice. Food Funct. 2021 May 11; 12(9):3831-3841. PMID: 33977958.
      Citations: 3     Fields:    Translation:Animals
    17. Guo S, Wu X, Zheng J, Smith SA, Dong P, Xiao H. Identification of 4'-Demethyltangeretin as a Major Urinary Metabolite of Tangeretin in Mice and Its Anti-inflammatory Activities. J Agric Food Chem. 2021 Apr 21; 69(15):4381-4391. PMID: 33787243.
      Citations: 2     Fields:    Translation:Animals
    18. Tan Y, Zhang Z, Liu J, Xiao H, McClements DJ. Correction: Factors impacting lipid digestion and nutraceutical bioaccessibility assessed by standardized gastrointestinal model (INFOGEST): oil droplet size. Food Funct. 2021 Mar 15; 12(5):2338. PMID: 33565535.
      Citations: 1     Fields:    
    19. Ahnan-Winarno AD, Cordeiro L, Winarno FG, Gibbons J, Xiao H. Tempeh: A semicentennial review on its health benefits, fermentation, safety, processing, sustainability, and affordability. Compr Rev Food Sci Food Saf. 2021 03; 20(2):1717-1767. PMID: 33569911.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    20. Tan Y, Zhang Z, Liu J, Xiao H, McClements DJ. Factors impacting lipid digestion and nutraceutical bioaccessibility assessed by standardized gastrointestinal model (INFOGEST): oil. Food Funct. 2020 Nov 18; 11(11):9936-9946. PMID: 33103174.
      Citations: 4     Fields:    Translation:Humans
    21. Lu Y, Wu Y, Chen X, Yang X, Xiao H. Water extract of shepherd's purse prevents high-fructose induced-liver injury by regulating glucolipid metabolism and gut microbiota. Food Chem. 2021 Apr 16; 342:128536. PMID: 33189481.
      Citations: 3     Fields:    Translation:Animals
    22. Tan Y, Zhang Z, Zhou H, Xiao H, McClements DJ. Factors impacting lipid digestion and ?-carotene bioaccessibility assessed by standardized gastrointestinal model (INFOGEST): oil droplet concentration. Food Funct. 2020 Aug 01; 11(8):7126-7137. PMID: 32749423.
      Citations: 5     Fields:    Translation:HumansAnimals
    23. Wu X, Li Z, Sun Y, Li F, Gao Z, Zheng J, Xiao H. Identification of Xanthomicrol as a Major Metabolite of 5-Demethyltangeretin in Mouse Gastrointestinal Tract and Its Inhibitory Effects on Colon Cancer Cells. Front Nutr. 2020; 7:103. PMID: 32850933.
    24. Song M, Lan Y, Wu X, Han Y, Wang M, Zheng J, Li Z, Li F, Zhou J, Xiao J, Cao Y, Xiao H. The chemopreventive effect of 5-demethylnobiletin, a unique citrus flavonoid, on colitis-driven colorectal carcinogenesis in mice is associated with its colonic metabolites. Food Funct. 2020 Jun 24; 11(6):4940-4952. PMID: 32459257.
      Citations: 9     Fields:    Translation:Animals
    25. Liu B, Wu R, Gong S, Xiao H, Thayumanavan S. In Situ Formation of Polymeric Nanoassemblies Using an Efficient Reversible Click Reaction. Angew Chem Int Ed Engl. 2020 08 24; 59(35):15135-15140. PMID: 32410309.
      Citations: 6     Fields:    
    26. Cao X, Han Y, Gu M, Du H, Song M, Zhu X, Ma G, Pan C, Wang W, Zhao E, Goulette T, Yuan B, Zhang G, Xiao H. Foodborne Titanium Dioxide Nanoparticles Induce Stronger Adverse Effects in Obese Mice than Non-Obese Mice: Gut Microbiota Dysbiosis, Colonic Inflammation, and Proteome Alterations. Small. 2020 09; 16(36):e2001858. PMID: 32519440.
      Citations: 34     Fields:    Translation:AnimalsPHPublic Health
    27. Wu X, Xue L, Tata A, Song M, Neto CC, Xiao H. Bioactive Components of Polyphenol-Rich and Non-Polyphenol-Rich Cranberry Fruit Extracts and Their Chemopreventive Effects on Colitis-Associated Colon Cancer. J Agric Food Chem. 2020 Jun 24; 68(25):6845-6853. PMID: 32390426.
      Citations: 12     Fields:    Translation:HumansAnimals
    28. Tu J, Zhao J, Liu G, Tang C, Han Y, Cao X, Jia J, Ji G, Xiao H. Solid state fermentation by Fomitopsis pinicola improves physicochemical and functional properties of wheat bran and the bran-containing products. Food Chem. 2020 Oct 30; 328:127046. PMID: 32470773.
      Citations: 6     Fields:    Translation:Animals
    29. Dai H, Leung CE, Corradini MG, Xiao H, Kinchla AJ. Increasing the nutritional value of strawberry puree by adding xylo-oligosaccharides. Heliyon. 2020 Apr; 6(4):e03769. PMID: 32373726.
    30. DiMarco-Crook C, Rakariyatham K, Li Z, Du Z, Zheng J, Wu X, Xiao H. Synergistic anticancer effects of curcumin and 3',4'-didemethylnobiletin in combination on colon cancer cells. J Food Sci. 2020 Apr; 85(4):1292-1301. PMID: 32144766.
      Citations: 7     Fields:    Translation:HumansCells
    31. Li F, Han Y, Cai X, Gu M, Sun J, Qi C, Goulette T, Song M, Li Z, Xiao H. Dietary resveratrol attenuated colitis and modulated gut microbiota in dextran sulfate sodium-treated mice. Food Funct. 2020 Jan 29; 11(1):1063-1073. PMID: 31825043.
      Citations: 31     Fields:    Translation:AnimalsCells
    32. Yao M, Li Z, Julian McClements D, Tang Z, Xiao H. Design of nanoemulsion-based delivery systems to enhance intestinal lymphatic transport of lipophilic food bioactives: Influence of oil type. Food Chem. 2020 Jul 01; 317:126229. PMID: 32078989.
      Citations: 8     Fields:    Translation:HumansCells
    33. Han Y, Xiao H. Whole Food-Based Approaches to Modulating Gut Microbiota and Associated Diseases. Annu Rev Food Sci Technol. 2020 03 25; 11:119-143. PMID: 31951487.
      Citations: 18     Fields:    Translation:Humans
    34. Han Y, Huang M, Li L, Cai X, Gao Z, Li F, Rakariyatham K, Song M, Fern?ndez Tom? S, Xiao H. Non-extractable polyphenols from cranberries: potential anti-inflammation and anti-colon-cancer agents. Food Funct. 2019 Dec 11; 10(12):7714-7723. PMID: 31750473.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    35. Yang H, Sanidad KZ, Wang W, Xie M, Gu M, Cao X, Xiao H, Zhang G. Triclocarban exposure exaggerates colitis and colon tumorigenesis: roles of gut microbiota involved. Gut Microbes. 2020 11 09; 12(1):1690364. PMID: 31760871.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    36. Sun Y, Han Y, Song M, Charoensinphon N, Zheng J, Qiu P, Wu X, Xiao H. Inhibitory effects of nobiletin and its major metabolites on lung tumorigenesis. Food Funct. 2019 Nov 01; 10(11):7444-7452. PMID: 31664275.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    37. Zhang Z, Li XM, Xiao H, Nowak-Wegrzyn A, Zhou P. IgE-binding epitope mapping of tropomyosin allergen (Exo m 1) from Exopalaemon modestus, the freshwater Siberian prawn. Food Chem. 2020 Mar 30; 309:125603. PMID: 31707198.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    38. Cai X, Han Y, Gu M, Song M, Wu X, Li Z, Li F, Goulette T, Xiao H. Dietary cranberry suppressed colonic inflammation and alleviated gut microbiota dysbiosis in dextran sodium sulfate-treated mice. Food Funct. 2019 Oct 16; 10(10):6331-6341. PMID: 31524900.
      Citations: 26     Fields:    Translation:HumansAnimals
    39. Zhang Z, Xiao H, Zhou P. Glycation by saccharides of different molecular sizes affected the allergenicity of shrimp tropomyosin via epitope loss and the generation of advanced glycation end products. Food Funct. 2019 Nov 01; 10(11):7042-7051. PMID: 31580362.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    40. Gu M, Sun J, Qi C, Cai X, Goulette T, Song M, You X, Sela DA, Xiao H. The gastrointestinal fate of limonin and its effect on gut microbiota in mice. Food Funct. 2019 Sep 01; 10(9):5521-5530. PMID: 31418448.
      Citations: 2     Fields:    Translation:AnimalsCells
    41. Goulette TR, Zhou J, Dixon WR, Normand MD, Peleg M, McClements DJ, Decker E, Xiao H. Kinetic parameters of thiamine degradation in NASA spaceflight foods determined by the endpoints method for long-term storage. Food Chem. 2020 Jan 01; 302:125365. PMID: 31442703.
      Citations: 1     Fields:    Translation:Animals
    42. Zhang Z, Li XM, Xiao H, Nowak-Wegrzyn A, Zhou P. Insight into the allergenicity of shrimp tropomyosin glycated by functional oligosaccharides containing advanced glycation end products. Food Chem. 2020 Jan 01; 302:125348. PMID: 31442704.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    43. Zhu X, Qiu Z, Ouyang W, Miao J, Xiong P, Mao D, Feng K, Li M, Luo M, Xiao H, Cao Y. Hepatic transcriptome and proteome analyses provide new insights into the regulator mechanism of dietary avicularin in diabetic mice. Food Res Int. 2019 11; 125:108570. PMID: 31554135.
      Citations: 7     Fields:    Translation:AnimalsCells
    44. Zhang Z, Xiao H, Zhang X, Zhou P. Insight into the effects of deglycosylation and glycation of shrimp tropomyosin on in vivo allergenicity and mast cell function. Food Funct. 2019 Jul 17; 10(7):3934-3941. PMID: 31197293.
      Citations: 5     Fields:    Translation:AnimalsCells
    45. Rakariyatham K, Du Z, Yuan B, Gao Z, Song M, Pan C, Han Y, Wu X, Tang Z, Zhang G, Xiao H. Inhibitory effects of 7,7'-bromo-curcumin on 12-O-tetradecanoylphorbol-13-acetate-induced skin inflammation. Eur J Pharmacol. 2019 Sep 05; 858:172479. PMID: 31228449.
      Citations: 4     Fields:    Translation:AnimalsCells
    46. Zhou H, Pandya JK, Tan Y, Liu J, Peng S, Muriel Mundo JL, He L, Xiao H, McClements DJ. Role of Mucin in Behavior of Food-Grade TiO2 Nanoparticles under Simulated Oral Conditions. J Agric Food Chem. 2019 May 22; 67(20):5882-5890. PMID: 31045357.
      Citations: 5     Fields:    Translation:HumansCells
    47. Zhang Z, Xiao H, Zhou P. Allergenicity suppression of tropomyosin from Exopalaemon modestus by glycation with saccharides of different molecular sizes. Food Chem. 2019 Aug 01; 288:268-275. PMID: 30902292.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    48. Han Y, Song M, Gu M, Ren D, Zhu X, Cao X, Li F, Wang W, Cai X, Yuan B, Goulette T, Zhang G, Xiao H. Dietary Intake of Whole Strawberry Inhibited Colonic Inflammation in Dextran-Sulfate-Sodium-Treated Mice via Restoring Immune Homeostasis and Alleviating Gut Microbiota Dysbiosis. J Agric Food Chem. 2019 Aug 21; 67(33):9168-9177. PMID: 30810035.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    49. Wang W, Yang J, Edin ML, Wang Y, Luo Y, Wan D, Yang H, Song CQ, Xue W, Sanidad KZ, Song M, Bisbee HA, Bradbury JA, Nan G, Zhang J, Shih PB, Lee KSS, Minter LM, Kim D, Xiao H, Liu JY, Hammock BD, Zeldin DC, Zhang G. Targeted Metabolomics Identifies the Cytochrome P450 Monooxygenase Eicosanoid Pathway as a Novel Therapeutic Target of Colon Tumorigenesis. Cancer Res. 2019 04 15; 79(8):1822-1830. PMID: 30803995.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    50. Rakariyatham K, Yang X, Gao Z, Song M, Han Y, Chen X, Xiao H. Synergistic chemopreventive effect of allyl isothiocyanate and sulforaphane on non-small cell lung carcinoma cells. Food Funct. 2019 Feb 20; 10(2):893-902. PMID: 30694275.
      Citations: 15     Fields:    Translation:HumansCells
    51. Sanidad KZ, Sukamtoh E, Xiao H, McClements DJ, Zhang G. Curcumin: Recent Advances in the Development of Strategies to Improve Oral Bioavailability. Annu Rev Food Sci Technol. 2019 03 25; 10:597-617. PMID: 30633561.
      Citations: 31     Fields:    Translation:Humans
    52. Li J, Frederick AM, Jin Y, Guo C, Xiao H, Wood RJ, Liu Z. The Prevention of a High Dose of Vitamin D or Its Combination with Sulforaphane on Intestinal Inflammation and Tumorigenesis in Apc1638N Mice Fed a High-Fat Diet. Mol Nutr Food Res. 2019 02; 63(4):e1800824. PMID: 30447137.
      Citations: 3     Fields:    Translation:Animals
    53. Zhang Z, Zhang R, Xiao H, Bhattacharya K, Bitounis D, Demokritou P, McClements DJ. Development of a standardized food model for studying the impact of food matrix effects on the gastrointestinal fate and toxicity of ingested nanomaterials. NanoImpact. 2019 Jan; 13:13-25. PMID: 31093583.
      Citations: 27     Fields:    
    54. Wu X, Song M, Cai X, Neto C, Tata A, Han Y, Wang Q, Tang Z, Xiao H. Chemopreventive Effects of Whole Cranberry (Vaccinium macrocarpon) on Colitis-Associated Colon Tumorigenesis. Mol Nutr Food Res. 2018 12; 62(24):e1800942. PMID: 30353672.
      Citations: 15     Fields:    Translation:Animals
    55. Sanidad KZ, Xiao H, Zhang G. Triclosan, a common antimicrobial ingredient, on gut microbiota and gut health. Gut Microbes. 2019; 10(3):434-437. PMID: 30453815.
      Citations: 16     Fields:    Translation:HumansAnimalsPHPublic Health
    56. Rakariyatham K, Wu X, Tang Z, Han Y, Wang Q, Xiao H. Synergism between luteolin and sulforaphane in anti-inflammation. Food Funct. 2018 Oct 17; 9(10):5115-5123. PMID: 30206627.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    57. Zhang Z, Xiao H, Zhang X, Zhou P. Conformation, allergenicity and human cell allergy sensitization of tropomyosin from Exopalaemon modestus: Effects of deglycosylation and Maillard reaction. Food Chem. 2019 Mar 15; 276:520-527. PMID: 30409628.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    58. Yang H, Wang W, Romano KA, Gu M, Sanidad KZ, Kim D, Yang J, Schmidt B, Panigrahy D, Pei R, Martin DA, Ozay EI, Wang Y, Song M, Bolling BW, Xiao H, Minter LM, Yang GY, Liu Z, Rey FE, Zhang G. A common antimicrobial additive increases colonic inflammation and colitis-associated colon tumorigenesis in mice. Sci Transl Med. 2018 05 30; 10(443). PMID: 29848663.
      Citations: 51     Fields:    Translation:AnimalsCells
    59. Wu X, Song M, Qiu P, Li F, Wang M, Zheng J, Wang Q, Xu F, Xiao H. A metabolite of nobiletin, 4'-demethylnobiletin and atorvastatin synergistically inhibits human colon cancer cell growth by inducing G0/G1 cell cycle arrest and apoptosis. Food Funct. 2018 Jan 24; 9(1):87-95. PMID: 29063088.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    60. You X, Einson JE, Lopez-Pena CL, Song M, Xiao H, McClements DJ, Sela DA. Food-grade cationic antimicrobial e-polylysine transiently alters the gut microbial community and predicted metagenome function in CD-1 mice. NPJ Sci Food. 2017; 1:8. PMID: 31304250.
    61. McClements DJ, Xiao H. Is nano safe in foods? Establishing the factors impacting the gastrointestinal fate and toxicity of organic and inorganic food-grade nanoparticles. NPJ Sci Food. 2017; 1:6. PMID: 31304248.
    62. McClements DJ, Xiao H. Designing food structure and composition to enhance nutraceutical bioactivity to support cancer inhibition. Semin Cancer Biol. 2017 10; 46:215-226. PMID: 28596014.
      Citations: 16     Fields:    Translation:Humans
    63. Song M, Lopez-Pena CL, McClements DJ, Decker EA, Xiao H. Safety evaluation and lipid-lowering effects of food-grade biopolymer complexes (e-polylysine-pectin) in mice fed a high-fat diet. Food Funct. 2017 May 24; 8(5):1822-1829. PMID: 28475188.
      Citations: 4     Fields:    Translation:Animals
    64. Yang H, Du Z, Wang W, Song M, Sanidad K, Sukamtoh E, Zheng J, Tian L, Xiao H, Liu Z, Zhang G. Structure-Activity Relationship of Curcumin: Role of the Methoxy Group in Anti-inflammatory and Anticolitis Effects of Curcumin. J Agric Food Chem. 2017 Jun 07; 65(22):4509-4515. PMID: 28513174.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    65. McClements DJ, Xiao H, Demokritou P. Physicochemical and colloidal aspects of food matrix effects on gastrointestinal fate of ingested inorganic nanoparticles. Adv Colloid Interface Sci. 2017 Aug; 246:165-180. PMID: 28552424.
      Citations: 30     Fields:    
    66. Wu X, Song M, Qiu P, Rakariyatham K, Li F, Gao Z, Cai X, Wang M, Xu F, Zheng J, Xiao H. Synergistic chemopreventive effects of nobiletin and atorvastatin on colon carcinogenesis. Carcinogenesis. 2017 04 01; 38(4):455-464. PMID: 28207072.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    67. Song M, Wu X, Charoensinphon N, Wang M, Zheng J, Gao Z, Xu F, Li Z, Li F, Zhou J, Xiao H. Dietary 5-demethylnobiletin inhibits cigarette carcinogen NNK-induced lung tumorigenesis in mice. Food Funct. 2017 Mar 22; 8(3):954-963. PMID: 28154877.
      Citations: 9     Fields:    Translation:HumansAnimals
    68. Chen X, Gao Z, Song M, Ouyang W, Wu X, Chen Y, Zhou L, William D, Cai X, Cao Y, Zhou S, Tang Z, Xiao H. Identification of terpenoids from Rubus corchorifolius L. f. leaves and their anti-proliferative effects on human cancer cells. Food Funct. 2017 Mar 22; 8(3):1052-1060. PMID: 28134947.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    69. Wu X, Song M, Gao Z, Sun Y, Wang M, Li F, Zheng J, Xiao H. Nobiletin and its colonic metabolites suppress colitis-associated colon carcinogenesis by down-regulating iNOS, inducing antioxidative enzymes and arresting cell cycle progression. J Nutr Biochem. 2017 04; 42:17-25. PMID: 28107678.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    70. Zhang H, Zheng J, Liu A, Xiao H, He L. Label-free Imaging and Characterization of Cancer Cell Responses to Polymethoxyflavones Using Raman Microscopy. J Agric Food Chem. 2016 Dec 28; 64(51):9708-9713. PMID: 27977189.
      Citations: 2     Fields:    Translation:HumansCells
    71. Cao X, Ma C, Gao Z, Zheng J, He L, McClements DJ, Xiao H. Characterization of the Interactions between Titanium Dioxide Nanoparticles and Polymethoxyflavones Using Surface-Enhanced Raman Spectroscopy. J Agric Food Chem. 2016 Dec 14; 64(49):9436-9441. PMID: 27960290.
      Citations: 14     Fields:    
    72. McClements DJ, DeLoid G, Pyrgiotakis G, Shatkin JA, Xiao H, Demokritou P. The Role of the Food Matrix and Gastrointestinal Tract in the assessment of biological properties of ingested engineered nanomaterials (iENMs): State of the science and knowledge gaps. NanoImpact. 2016 Jul; 3-4:47-57. PMID: 29568810.
      Citations: 42     Fields:    
    73. Song M, Charoensinphon N, Wu X, Zheng J, Gao Z, Xu F, Wang M, Xiao H. Inhibitory Effects of Metabolites of 5-Demethylnobiletin on Human Nonsmall Cell Lung Cancer Cells. J Agric Food Chem. 2016 Jun 22; 64(24):4943-9. PMID: 27219898.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    74. Sanidad KZ, Sukamtoh E, Wang W, Du Z, Florio E, He L, Xiao H, Decker EA, Zhang G. Oxidative Conversion Mediates Antiproliferative Effects of tert-Butylhydroquinone: Structure and Activity Relationship Study. J Agric Food Chem. 2016 May 18; 64(19):3743-8. PMID: 27111399.
      Citations: 1     Fields:    Translation:Cells
    75. Zhang R, Zhang Z, Zou L, Xiao H, Zhang G, Decker EA, McClements DJ. Enhancement of carotenoid bioaccessibility from carrots using excipient emulsions: influence of particle size of digestible lipid droplets. Food Funct. 2016 Jan; 7(1):93-103. PMID: 26583923.
      Citations: 9     Fields:    Translation:AnimalsCells
    76. Wu X, Song M, Rakariyatham K, Zheng J, Wang M, Xu F, Gao Z, Xiao H. Inhibitory Effects of 4'-Demethylnobiletin, a Metabolite of Nobiletin, on 12-O-Tetradecanoylphorbol-13-acetate (TPA)-Induced Inflammation in Mouse Ears. J Agric Food Chem. 2015 Dec 30; 63(51):10921-7. PMID: 26651527.
      Citations: 10     Fields:    Translation:AnimalsCells
    77. Chen J, Song M, Wu X, Zheng J, He L, McClements DJ, Decker E, Xiao H. Direct Fluorescent Detection of a Polymethoxyflavone in Cell Culture and Mouse Tissue. J Agric Food Chem. 2015 Dec 16; 63(49):10620-7. PMID: 26618604.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    78. Zhang R, Zhang Z, Zou L, Xiao H, Zhang G, Decker EA, McClements DJ. Enhancing Nutraceutical Bioavailability from Raw and Cooked Vegetables Using Excipient Emulsions: Influence of Lipid Type on Carotenoid Bioaccessibility from Carrots. J Agric Food Chem. 2015 Dec 09; 63(48):10508-17. PMID: 26585671.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    79. Wu X, Song M, Rakariyatham K, Zheng J, Guo S, Tang Z, Zhou S, Xiao H. Anti-inflammatory effects of 4'-demethylnobiletin, a major metabolite of nobiletin. J Funct Foods. 2015 Dec 01; 19(Pt A):278-287. PMID: 26770275.
    80. Wu X, Song M, Wang M, Zheng J, Gao Z, Xu F, Zhang G, Xiao H. Chemopreventive effects of nobiletin and its colonic metabolites on colon carcinogenesis. Mol Nutr Food Res. 2015 Dec; 59(12):2383-94. PMID: 26445322.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    81. Wang W, Sukamtoh E, Xiao H, Zhang G. Curcumin inhibits lymphangiogenesis in vitro and in vivo. Mol Nutr Food Res. 2015 Dec; 59(12):2345-54. PMID: 26375757.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    82. Yao M, He L, McClements DJ, Xiao H. Uptake of Gold Nanoparticles by Intestinal Epithelial Cells: Impact of Particle Size on Their Absorption, Accumulation, and Toxicity. J Agric Food Chem. 2015 Sep 16; 63(36):8044-9. PMID: 26313743.
      Citations: 26     Fields:    Translation:HumansCells
    83. Lopez-Pena CL, Song M, Xiao H, Decker EA, McClements DJ. Potential impact of biopolymers (e-polylysine and/or pectin) on gastrointestinal fate of foods: In vitro study. Food Res Int. 2015 Oct; 76(Pt 3):769-776. PMID: 28455062.
      Citations: 1     Fields:    
    84. Lopez-Pena CL, Zheng B, Sela DA, Decker EA, Xiao H, McClements DJ. Impact of e-polylysine and pectin on the potential gastrointestinal fate of emulsified lipids: In vitro mouth, stomach and small intestine model. Food Chem. 2016 Feb 01; 192:857-64. PMID: 26304421.
      Citations: 3     Fields:    
    85. DiMarco-Crook C, Xiao H. Diet-based strategies for cancer chemoprevention: the role of combination regimens using dietary bioactive components. Annu Rev Food Sci Technol. 2015; 6:505-26. PMID: 25884285.
      Citations: 27     Fields:    Translation:Humans
    86. McClements DJ, Li F, Xiao H. The Nutraceutical Bioavailability Classification Scheme: Classifying Nutraceuticals According to Factors Limiting their Oral Bioavailability. Annu Rev Food Sci Technol. 2015; 6:299-327. PMID: 25705933.
      Citations: 37     Fields:    
    87. Xia Z, McClements DJ, Xiao H. Influence of physical state of ?-carotene (crystallized versus solubilized) on bioaccessibility. J Agric Food Chem. 2015 Jan 28; 63(3):990-7. PMID: 25560778.
      Citations: 4     Fields:    Translation:HumansCells
    88. Yang Y, Decker EA, Xiao H, McClements DJ. Enhancing vitamin E bioaccessibility: factors impacting solubilization and hydrolysis of a-tocopherol acetate encapsulated in emulsion-based delivery systems. Food Funct. 2015 Jan; 6(1):84-97. PMID: 25312787.
      Citations: 7     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    89. McClements DJ, Xiao H. Excipient foods: designing food matrices that improve the oral bioavailability of pharmaceuticals and nutraceuticals. Food Funct. 2014 Jul 25; 5(7):1320-33. PMID: 24760211.
      Citations: 18     Fields:    
    90. Chen J, Zheng J, McClements DJ, Xiao H. Tangeretin-loaded protein nanoparticles fabricated from zein/?-lactoglobulin: preparation, characterization, and functional performance. Food Chem. 2014 Sep 01; 158:466-72. PMID: 24731371.
      Citations: 12     Fields:    
    91. Yao M, Xiao H, McClements DJ. Delivery of lipophilic bioactives: assembly, disassembly, and reassembly of lipid nanoparticles. Annu Rev Food Sci Technol. 2014; 5:53-81. PMID: 24328432.
      Citations: 21     Fields:    Translation:HumansCells
    92. Yao M, Chen J, Zheng J, Song M, McClements DJ, Xiao H. Enhanced lymphatic transport of bioactive lipids: cell culture study of polymethoxyflavone incorporation into chylomicrons. Food Funct. 2013 Nov; 4(11):1662-7. PMID: 24084938.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    93. Zheng J, Fang X, Cao Y, Xiao H, He L. Monitoring the chemical production of citrus-derived bioactive 5-demethylnobiletin using surface-enhanced Raman spectroscopy. J Agric Food Chem. 2013 Aug 28; 61(34):8079-83. PMID: 23885986.
      Citations: 1     Fields:    Translation:Animals
    94. Charoensinphon N, Qiu P, Dong P, Zheng J, Ngauv P, Cao Y, Li S, Ho CT, Xiao H. 5-demethyltangeretin inhibits human nonsmall cell lung cancer cell growth by inducing G2/M cell cycle arrest and apoptosis. Mol Nutr Food Res. 2013 Dec; 57(12):2103-11. PMID: 23926120.
      Citations: 19     Fields:    Translation:HumansCells
    95. Zheng J, Song M, Dong P, Qiu P, Guo S, Zhong Z, Li S, Ho CT, Xiao H. Identification of novel bioactive metabolites of 5-demethylnobiletin in mice. Mol Nutr Food Res. 2013 Nov; 57(11):1999-2007. PMID: 23894027.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    96. Rao J, Decker EA, Xiao H, McClements DJ. Nutraceutical nanoemulsions: influence of carrier oil composition (digestible versus indigestible oil) on ?-carotene bioavailability. J Sci Food Agric. 2013 Oct; 93(13):3175-83. PMID: 23649644.
      Citations: 11     Fields:    
    97. Mao Y, Dubot M, Xiao H, McClements DJ. Interfacial engineering using mixed protein systems: emulsion-based delivery systems for encapsulation and stabilization of ?-carotene. J Agric Food Chem. 2013 May 29; 61(21):5163-9. PMID: 23647430.
      Citations: 5     Fields:    
    98. Li Y, Xiao H, McClements DJ. Encapsulation and Delivery of Crystalline Hydrophobic Nutraceuticals using Nanoemulsions: Factors Affecting Polymethoxyflavone Solubility. Food Biophys. 2012 Dec 01; 7(4):341-353. PMID: 23646037.
    99. Qian C, Decker EA, Xiao H, McClements DJ. Nanoemulsion delivery systems: influence of carrier oil on ?-carotene bioaccessibility. Food Chem. 2012 Dec 01; 135(3):1440-7. PMID: 22953878.
      Citations: 50     Fields:    Translation:Humans
    100. Qian C, Decker EA, Xiao H, McClements DJ. Inhibition of ?-carotene degradation in oil-in-water nanoemulsions: influence of oil-soluble and water-soluble antioxidants. Food Chem. 2012 Dec 01; 135(3):1036-43. PMID: 22953821.
      Citations: 11     Fields:    
    101. Qian C, Decker EA, Xiao H, McClements DJ. Physical and chemical stability of ?-carotene-enriched nanoemulsions: Influence of pH, ionic strength, temperature, and emulsifier type. Food Chem. 2012 Jun 01; 132(3):1221-1229. PMID: 29243604.
      Citations: 43     Fields:    
    102. McClements DJ, Xiao H. Potential biological fate of ingested nanoemulsions: influence of particle characteristics. Food Funct. 2012 Mar; 3(3):202-20. PMID: 22105669.
      Citations: 32     Fields:    Translation:Humans
    103. Nutakul W, Sobers HS, Qiu P, Dong P, Decker EA, McClements DJ, Xiao H. Inhibitory effects of resveratrol and pterostilbene on human colon cancer cells: a side-by-side comparison. J Agric Food Chem. 2011 Oct 26; 59(20):10964-70. PMID: 21936500.
      Citations: 30     Fields:    Translation:HumansCells
    104. Li Y, Zheng J, Xiao H, McClements DJ. Nanoemulsion-based delivery systems for poorly water-soluble bioactive compounds: Influence of formulation parameters on Polymethoxyflavone crystallization. Food Hydrocoll. 2012 Jun 01; 27(2):517-528. PMID: 22685367.
    105. Qiu P, Guan H, Dong P, Guo S, Zheng J, Li S, Chen Y, Ho CT, Pan MH, McClements DJ, Xiao H. The inhibitory effects of 5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone on human colon cancer cells. Mol Nutr Food Res. 2011 Oct; 55(10):1523-32. PMID: 21648071.
      Citations: 7     Fields:    Translation:HumansCells
    106. Hu M, Li Y, Decker EA, Xiao H, McClements DJ. Influence of tripolyphosphate cross-linking on the physical stability and lipase digestibility of chitosan-coated lipid droplets. J Agric Food Chem. 2010 Jan 27; 58(2):1283-9. PMID: 19921835.
      Citations: 7     Fields:    Translation:Humans
    107. Dong P, Qiu P, Zhu Y, Li S, Ho CT, McClements DJ, Xiao H. Simultaneous determination of four 5-hydroxy polymethoxyflavones by reversed-phase high performance liquid chromatography with electrochemical detection. J Chromatogr A. 2010 Jan 29; 1217(5):642-7. PMID: 20022018.
      Citations: 10     Fields:    Translation:Animals
    108. Li Y, Le Maux S, Xiao H, McClements DJ. Emulsion-based delivery systems for tributyrin, a potential colon cancer preventative agent. J Agric Food Chem. 2009 Oct 14; 57(19):9243-9. PMID: 19731938.
      Citations: 14     Fields:    Translation:HumansCells
    109. Xiao H, Yang CS, Li S, Jin H, Ho CT, Patel T. Monodemethylated polymethoxyflavones from sweet orange (Citrus sinensis) peel inhibit growth of human lung cancer cells by apoptosis. Mol Nutr Food Res. 2009 Mar; 53(3):398-406. PMID: 19065586.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    110. Xiao H, Yang CS. Combination regimen with statins and NSAIDs: a promising strategy for cancer chemoprevention. Int J Cancer. 2008 Sep 01; 123(5):983-90. PMID: 18548583.
      Citations: 32     Fields:    Translation:HumansAnimals
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