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Mechanisms and applications of immune stimulatory CpG oligodeoxynucleotides.
CpG DNA rescue from anti-IgM-induced WEHI-231 B lymphoma apoptosis via modulation of I kappa B alpha and I kappa B beta and sustained activation of nuclear factor-kappa B/c-Rel.
Cancer and inflammation: promise for biologic therapy.
Multicenter phase I trial of the mitogen-activated protein kinase 1/2 inhibitor BAY 86-9766 in patients with advanced cancer.
P-chirality-dependent immune activation by phosphorothioate CpG oligodeoxynucleotides.
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P-chirality-dependent immune activation by phosphorothioate CpG oligodeoxynucleotides.
Krieg AM, Guga P, Stec W. P-chirality-dependent immune activation by phosphorothioate CpG oligodeoxynucleotides. Oligonucleotides. 2003; 13(6):491-9.
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PubMed
subject areas
Adjuvants, Immunologic
Animals
B-Lymphocytes
Cells, Cultured
I-kappa B Kinase
JNK Mitogen-Activated Protein Kinases
Mice
Mice, Inbred BALB C
Mitogen-Activated Protein Kinases
Oligodeoxyribonucleotides
Phosphates
Phosphorylation
Stereoisomerism
authors with profiles
Arthur M Krieg MD