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Interacting-heads motif has been conserved as a mechanism of myosin II inhibition since before the origin of animals.

Lee KH, Sulbar?n G, Yang S, Mun JY, Alamo L, Pinto A, Sato O, Ikebe M, Liu X, Korn ED, Sarsoza F, Bernstein SI, Padr?n R, Craig R. Interacting-heads motif has been conserved as a mechanism of myosin II inhibition since before the origin of animals. Proc Natl Acad Sci U S A. 2018 02 27; 115(9):E1991-E2000.

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