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Ping Lu PhD

InstitutionUMass Chan Medical School
DepartmentMicrobiology and Physiological Systems
AddressUMass Chan Medical School
368 Plantation Street
Worcester MA 01605
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentMicrobiology and Physiological Systems

    Collapse Biography 
    Collapse education and training
    Huazhong Agricultural University, Wuhan, , ChinaBSAnimal Science
    Zhejiang University, Hangzhou, , ChinaMSBiology
    Zhejiang University, Hangzhou, , ChinaPHDBiology

    Collapse Overview 
    Collapse Summary
    Focus: Study the physiology and pathophysiology of smooth muscle with state-of-art technology ranging from molecular biology, gene editing, calcium imaging, organ culture, and transgenic animal model.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Qu M, Lu P, Bellve K, Fogarty K, Lifshitz L, Shi F, Zhuge R. Smooth muscle cell-specific TMEM16A deletion does not alter Ca2+ signaling, uterine contraction, gestation length, or litter size in mice?. Biol Reprod. 2019 08 01; 101(2):318-327. PMID: 31175367.
      Citations: 4     Fields:    Translation:AnimalsCells
    2. Feng M, Wang Z, Liu Z, Liu D, Zheng K, Lu P, Liu C, Zhang M, Li J. The RyR-ClCa -VDCC axis contributes to spontaneous tone in urethral smooth muscle. J Cell Physiol. 2019 12; 234(12):23256-23267. PMID: 31161632.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    3. Chen J, Zhang E, Zhang W, Liu Z, Lu P, Zhu T, Yin Z, Backman LJ, Liu H, Chen X, Ouyang H. Fos Promotes Early Stage Teno-Lineage Differentiation of Tendon Stem/Progenitor Cells in Tendon. Stem Cells Transl Med. 2017 11; 6(11):2009-2019. PMID: 29024580.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    4. Wang P, Zhao W, Sun J, Tao T, Chen X, Zheng YY, Zhang CH, Chen Z, Gao YQ, She F, Li YQ, Wei LS, Lu P, Chen CP, Zhou J, Wang DQ, Chen L, Shi XH, Deng L, ZhuGe R, Chen HQ, Zhu MS. Inflammatory mediators mediate airway smooth muscle contraction through a G protein-coupled receptor-transmembrane protein 16A-voltage-dependent Ca2+ channel axis and contribute to bronchial hyperresponsiveness in asthma. J Allergy Clin Immunol. 2018 04; 141(4):1259-1268.e11. PMID: 28754608.
      Citations: 20     Fields:    Translation:AnimalsCells
    5. Xiong S, Zhang X, Lu P, Wu Y, Wang Q, Sun H, Heng BC, Bunpetch V, Zhang S, Ouyang H. A Gelatin-sulfonated Silk Composite Scaffold based on 3D Printing Technology Enhances Skin Regeneration by Stimulating Epidermal Growth and Dermal Neovascularization. Sci Rep. 2017 06 27; 7(1):4288. PMID: 28655891.
      Citations: 41     Fields:    Translation:HumansCells
    6. Zheng K, Lu P, Delpapa E, Bellve K, Deng R, Condon JC, Fogarty K, Lifshitz LM, Simas TAM, Shi F, ZhuGe R. Bitter taste receptors as targets for tocolytics in preterm labor therapy. FASEB J. 2017 09; 31(9):4037-4052. PMID: 28559440.
      Citations: 16     Fields:    Translation:HumansAnimals
    7. Wang D, Lu P, Liu Y, Chen L, Zhang R, Sui W, Dumitru AG, Chen X, Wen F, Ouyang HW, Ji J. Isolation of Live Premature Senescent Cells Using FUCCI Technology. Sci Rep. 2016 08 09; 6:30705. PMID: 27503759.
      Citations: 3     Fields:    Translation:HumansCells
    8. Jiang Y, Cai Y, Zhang W, Yin Z, Hu C, Tong T, Lu P, Zhang S, Neculai D, Tuan RS, Ouyang HW. Human Cartilage-Derived Progenitor Cells From Committed Chondrocytes for Efficient Cartilage Repair and Regeneration. Stem Cells Transl Med. 2016 Jun; 5(6):733-44. PMID: 27130221.
      Citations: 74     Fields:    Translation:HumansCells
    9. Zhang CH, Wang P, Liu DH, Chen CP, Zhao W, Chen X, Chen C, He WQ, Qiao YN, Tao T, Sun J, Peng YJ, Lu P, Zheng K, Craige SM, Lifshitz LM, Keaney JF, Fogarty KE, ZhuGe R, Zhu MS. The molecular basis of the genesis of basal tone in internal anal sphincter. Nat Commun. 2016 Apr 22; 7:11358. PMID: 27101932.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    10. Hu JJ, Yin Z, Shen WL, Xie YB, Zhu T, Lu P, Cai YZ, Kong MJ, Heng BC, Zhou YT, Chen WS, Chen X, Ouyang HW. Pharmacological Regulation of In Situ Tissue Stem Cells Differentiation for Soft Tissue Calcification Treatment. Stem Cells. 2016 Apr; 34(4):1083-96. PMID: 26851078.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    11. Wang J, Wang J, Lu P, Cai Y, Wang Y, Hong L, Ren H, Heng BC, Liu H, Zhou J, Ouyang H. Local delivery of FTY720 in PCL membrane improves SCI functional recovery by reducing reactive astrogliosis. Biomaterials. 2015 Sep; 62:76-87. PMID: 26036174.
      Citations: 16     Fields:    Translation:Animals
    12. Xia Q, Zhu S, Wu Y, Wang J, Cai Y, Chen P, Li J, Heng BC, Ouyang HW, Lu P. Intra-articular transplantation of atsttrin-transduced mesenchymal stem cells ameliorate osteoarthritis development. Stem Cells Transl Med. 2015 May; 4(5):523-31. PMID: 25824140.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    13. Zhang C, Yuan H, Liu H, Chen X, Lu P, Zhu T, Yang L, Yin Z, Heng BC, Zhang Y, Ouyang H. Well-aligned chitosan-based ultrafine fibers committed teno-lineage differentiation of human induced pluripotent stem cells for Achilles tendon regeneration. Biomaterials. 2015; 53:716-30. PMID: 25890767.
      Citations: 59     Fields:    Translation:HumansCells
    14. Liu H, Zhang C, Zhu S, Lu P, Zhu T, Gong X, Zhang Z, Hu J, Yin Z, Heng BC, Chen X, Ouyang HW. Mohawk promotes the tenogenesis of mesenchymal stem cells through activation of the TGF? signaling pathway. Stem Cells. 2015 Feb; 33(2):443-55. PMID: 25332192.
      Citations: 79     Fields:    Translation:HumansAnimalsCells
    15. Ren H, Han M, Zhou J, Zheng ZF, Lu P, Wang JJ, Wang JQ, Mao QJ, Gao JQ, Ouyang HW. Repair of spinal cord injury by inhibition of astrocyte growth and inflammatory factor synthesis through local delivery of flavopiridol in PLGA nanoparticles. Biomaterials. 2014 Aug; 35(24):6585-94. PMID: 24811262.
      Citations: 35     Fields:    Translation:AnimalsCells
    16. Liu H, Zhu S, Zhang C, Lu P, Hu J, Yin Z, Ma Y, Chen X, OuYang H. Crucial transcription factors in tendon development and differentiation: their potential for tendon regeneration. Cell Tissue Res. 2014 May; 356(2):287-98. PMID: 24705622.
      Citations: 44     Fields:    Translation:HumansAnimals
    17. Chen P, Zhu S, Wang Y, Mu Q, Wu Y, Xia Q, Zhang X, Sun H, Tao J, Hu H, Lu P, Ouyang H. The amelioration of cartilage degeneration by ADAMTS-5 inhibitor delivered in a hyaluronic acid hydrogel. Biomaterials. 2014 Mar; 35(9):2827-36. PMID: 24424207.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    18. Zhou J, Lu P, Ren H, Zheng Z, Ji J, Liu H, Jiang F, Ling S, Heng BC, Hu X, Ouyang H. 17?-estradiol protects human eyelid-derived adipose stem cells against cytotoxicity and increases transplanted cell survival in spinal cord injury. J Cell Mol Med. 2014 Feb; 18(2):326-43. PMID: 24373095.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    19. Zhu S, Lu P, Liu H, Chen P, Wu Y, Wang Y, Sun H, Zhang X, Xia Q, Heng BC, Zhou Y, Ouyang HW. Inhibition of Rac1 activity by controlled release of NSC23766 from chitosan microspheres effectively ameliorates osteoarthritis development in vivo. Ann Rheum Dis. 2015 Jan; 74(1):285-93. PMID: 24257023.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    20. Lu P, Zhang GR, Cai YZ, Heng BC, Ren H, Wang LL, Ji J, Zou XH, Ouyang HW. Lentiviral-encoded shRNA silencing of proteoglycan decorin enhances tendon repair and regeneration within a rat model. Cell Transplant. 2013; 22(9):1507-17. PMID: 23295185.
      Citations: 6     Fields:    Translation:AnimalsCells
    21. Lu P, Zhang GR, Song XH, Zou XH, Wang LL, Ouyang HW. Col V siRNA engineered tenocytes for tendon tissue engineering. PLoS One. 2011; 6(6):e21154. PMID: 21713001.
      Citations: 7     Fields:    Translation:AnimalsCells
    22. Hu CX, Xu ZR, Li WF, Niu D, Dong N, Lu P, Fu LL. Secretory expression of K88 (F4) fimbrial adhesin FaeG by recombinant Lactococcus lactis for oral vaccination and its protective immune response in mice. Biotechnol Lett. 2009 Jul; 31(7):991-7. PMID: 19277476.
      Citations: 5     Fields:    Translation:AnimalsCells
    23. Lu P, Feng MG. Bifunctional enhancement of a beta-glucanase-xylanase fusion enzyme by optimization of peptide linkers. Appl Microbiol Biotechnol. 2008 Jun; 79(4):579-87. PMID: 18415095.
      Citations: 46     Fields:    Translation:Cells
    24. Protein secretion pathways in Bacillus subtilis: implication for optimization of heterologous protein secretion. Biotechnol Adv. 2007 Jan-Feb; 25(1):1-12. PMID: 16997527.
      Citations: 42     Fields:    Translation:HumansCells
    25. Lu P, Feng MG, Li WF, Hu CX. Construction and characterization of a bifunctional fusion enzyme of Bacillus-sourced beta-glucanase and xylanase expressed in Escherichia coli. FEMS Microbiol Lett. 2006 Aug; 261(2):224-30. PMID: 16907724.
      Citations: 12     Fields:    Translation:Cells
    26. Li WF, Zhou XX, Lu P. Structural features of thermozymes. Biotechnol Adv. 2005 Jun; 23(4):271-81. PMID: 15848038.
      Citations: 56     Fields:    Translation:Cells
    27. Li W, Zhou X, Lu P. Bottlenecks in the expression and secretion of heterologous proteins in Bacillus subtilis. Res Microbiol. 2004 Oct; 155(8):605-10. PMID: 15380546.
      Citations: 27     Fields:    Translation:Cells
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