S100 Calcium-Binding Protein A4
"S100 Calcium-Binding Protein A4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An S100 protein characterized by four helix bundles that form N- and C-terminal EF HAND MOTIFS. It functions as a homodimer and interacts with both intracellular and extracellular signaling proteins. Aberrant S100A4 activity is associated with NEOPLASM METASTASIS; FIBROSIS; and RHEUMATOID ARTHRITIS.
| Descriptor ID |
D000071999
|
| MeSH Number(s) |
D12.776.157.125.750.813
|
| Concept/Terms |
S100 Calcium-Binding Protein A4- S100 Calcium-Binding Protein A4
- S100 Calcium Binding Protein A4
- Metastasin Protein
- Placental Calcium-Binding Protein
- Calcium-Binding Protein, Placental
- Placental Calcium Binding Protein
- Calvasculin Protein
- Fibroblast-Specific Protein 1
- Fibroblast Specific Protein 1
- S100A4 Protein
|
Below are MeSH descriptors whose meaning is more general than "S100 Calcium-Binding Protein A4".
Below are MeSH descriptors whose meaning is more specific than "S100 Calcium-Binding Protein A4".
This graph shows the total number of publications written about "S100 Calcium-Binding Protein A4" by people in this website by year, and whether "S100 Calcium-Binding Protein A4" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "S100 Calcium-Binding Protein A4" by people in Profiles.
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Abdelfattah N, Kumar P, Wang C, Leu JS, Flynn WF, Gao R, Baskin DS, Pichumani K, Ijare OB, Wood SL, Powell SZ, Haviland DL, Parker Kerrigan BC, Lang FF, Prabhu SS, Huntoon KM, Jiang W, Kim BYS, George J, Yun K. Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target. Nat Commun. 2022 02 09; 13(1):767.
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Verma SK, Leikina E, Melikov K, Gebert C, Kram V, Young MF, Uygur B, Chernomordik LV. Cell-surface phosphatidylserine regulates osteoclast precursor fusion. J Biol Chem. 2018 01 05; 293(1):254-270.
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Badyal SK, Basran J, Bhanji N, Kim JH, Chavda AP, Jung HS, Craig R, Elliott PR, Irvine AF, Barsukov IL, Kriajevska M, Bagshaw CR. Mechanism of the Ca?+-dependent interaction between S100A4 and tail fragments of nonmuscle myosin heavy chain IIA. J Mol Biol. 2011 Jan 28; 405(4):1004-26.
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Kim TH, Kim HI, Soung YH, Shaw LA, Chung J. Integrin (alpha6beta4) signals through Src to increase expression of S100A4, a metastasis-promoting factor: implications for cancer cell invasion. Mol Cancer Res. 2009 Oct; 7(10):1605-12.
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Harris MA, Yang H, Low BE, Mukherjee J, Mukherje J, Guha A, Bronson RT, Shultz LD, Israel MA, Yun K. Cancer stem cells are enriched in the side population cells in a mouse model of glioma. Cancer Res. 2008 Dec 15; 68(24):10051-9.