"ADAMTS4 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An ADAMTS protease similar to ADAMTS5 PROTEIN. It contains a single C-terminal thrombospondin (TS) motif and cleaves AGGRECAN in CARTILAGE. It may also be involved in the destruction of aggrecan in ARTHRITIS.
| Descriptor ID |
D000071121
|
| MeSH Number(s) |
D08.811.277.656.675.374.102.500.844 D09.400.430.500.500.844 D12.776.395.033.500.844 D12.776.860.300.085.844
|
| Concept/Terms |
ADAMTS4 Protein- ADAMTS4 Protein
- Aggrecanase-1
- Aggrecanase 1
- A Disintegrin And Metalloproteinase With Thrombospondin Motifs 4 Protein
- ADAMTS-4 Protein
- ADAMTS 4 Protein
|
Below are MeSH descriptors whose meaning is more general than "ADAMTS4 Protein".
Below are MeSH descriptors whose meaning is more specific than "ADAMTS4 Protein".
This graph shows the total number of publications written about "ADAMTS4 Protein" by people in this website by year, and whether "ADAMTS4 Protein" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 0 | 2 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "ADAMTS4 Protein" by people in Profiles.
-
Wang L, Pawlak E, Johnson PJ, Belknap JK, Alfandari D, Black SJ. Effects of cleavage by a disintegrin and metalloproteinase with thrombospondin motifs-4 on gene expression and protein content of versican and aggrecan in the digital laminae of horses with starch gruel-induced laminitis. Am J Vet Res. 2012 Jul; 73(7):1047-56.
-
Pawlak E, Wang L, Johnson PJ, Nuovo G, Taye A, Belknap JK, Alfandari D, Black SJ. Distribution and processing of a disintegrin and metalloproteinase with thrombospondin motifs-4, aggrecan, versican, and hyaluronan in equine digital laminae. Am J Vet Res. 2012 Jul; 73(7):1035-46.