"Xanthine Oxidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An iron-molybdenum flavoprotein containing FLAVIN-ADENINE DINUCLEOTIDE that oxidizes hypoxanthine, some other purines and pterins, and aldehydes. Deficiency of the enzyme, an autosomal recessive trait, causes xanthinuria.
| Descriptor ID |
D014969
|
| MeSH Number(s) |
D08.811.682.047.928
|
| Concept/Terms |
Xanthine Oxidase- Xanthine Oxidase
- Oxidase, Xanthine
- Hypoxanthine Oxidase
- Oxidase, Hypoxanthine
- Purine-Xanthine Oxidase
- Oxidase, Purine-Xanthine
- Purine Xanthine Oxidase
- Hypoxanthine Dehydrogenase
- Dehydrogenase, Hypoxanthine
- Hypoxanthine-Xanthine Oxidase
- Hypoxanthine Xanthine Oxidase
- Oxidase, Hypoxanthine-Xanthine
|
Below are MeSH descriptors whose meaning is more general than "Xanthine Oxidase".
Below are MeSH descriptors whose meaning is more specific than "Xanthine Oxidase".
This graph shows the total number of publications written about "Xanthine Oxidase" by people in this website by year, and whether "Xanthine Oxidase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Xanthine Oxidase" by people in Profiles.
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M?nzel T, Gori T, Keaney JF, Maack C, Daiber A. Pathophysiological role of oxidative stress in systolic and diastolic heart failure and its therapeutic implications. Eur Heart J. 2015 Oct 07; 36(38):2555-64.
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Kataoka H, Yang K, Rock KL. The xanthine oxidase inhibitor Febuxostat reduces tissue uric acid content and inhibits injury-induced inflammation in the liver and lung. Eur J Pharmacol. 2015 Jan 05; 746:174-9.
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Bauer JA, Moffatt-Bruce SD, Elton TS, Feldman D. Purine metabolism in heart failure: oxidant biology and therapeutic indications. Congest Heart Fail. 2008 Sep-Oct; 14(5):283-4.
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Loftus JP, Belknap JK, Stankiewicz KM, Black SJ. Laminar xanthine oxidase, superoxide dismutase and catalase activities in the prodromal stage of black-walnut induced equine laminitis. Equine Vet J. 2007 Jan; 39(1):48-53.
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Wendt MC, Daiber A, Kleschyov AL, M?lsch A, Sydow K, Schulz E, Chen K, Keaney JF, Lass?gue B, Walter U, Griendling KK, M?nzel T. Differential effects of diabetes on the expression of the gp91phox homologues nox1 and nox4. Free Radic Biol Med. 2005 Aug 01; 39(3):381-91.
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Schulz E, Anter E, Keaney JF. Oxidative stress, antioxidants, and endothelial function. Curr Med Chem. 2004 May; 11(9):1093-104.
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Gil J, Almeida S, Oliveira CR, Rego AC. Cytosolic and mitochondrial ROS in staurosporine-induced retinal cell apoptosis. Free Radic Biol Med. 2003 Dec 01; 35(11):1500-14.
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Wang J, Van Praagh A, Hamilton E, Wang Q, Zou B, Muranjan M, Murphy NB, Black SJ. Serum xanthine oxidase: origin, regulation, and contribution to control of trypanosome parasitemia. Antioxid Redox Signal. 2002 Feb; 4(1):161-78.
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Black SJ, Sicard EL, Murphy N, Nolan D. Innate and acquired control of trypanosome parasitaemia in Cape buffalo. Int J Parasitol. 2001 May 01; 31(5-6):562-5.
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Wang Q, Hamilton E, Black SJ. Purine requirements for the expression of Cape buffalo serum trypanocidal activity. Comp Biochem Physiol C Toxicol Pharmacol. 2000 Jan; 125(1):25-32.