Organic Cation Transporter 2
"Organic Cation Transporter 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Organic cation transporter consisting of twelve transmembrane domains and expressed primarily in the kidney. It transports a wide range of metabolites, drugs, and neurotransmitters from the blood to the KIDNEY TUBULES, including DOPAMINE; SEROTONIN; CHOLINE; and CISPLATIN.
Descriptor ID |
D000075102
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MeSH Number(s) |
D12.776.157.530.450.250.812.625 D12.776.157.530.937.612.625 D12.776.543.585.450.250.812.625 D12.776.543.585.937.701.625
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Organic Cation Transporter 2".
Below are MeSH descriptors whose meaning is more specific than "Organic Cation Transporter 2".
This graph shows the total number of publications written about "Organic Cation Transporter 2" by people in this website by year, and whether "Organic Cation Transporter 2" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2010 | 0 | 1 | 1 |
2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Organic Cation Transporter 2" by people in Profiles.
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Nieskens TTG, Persson M, Kelly EJ, Sj?gren AK. A Multicompartment Human Kidney Proximal Tubule-on-a-Chip Replicates Cell Polarization-Dependent Cisplatin Toxicity. Drug Metab Dispos. 2020 12; 48(12):1303-1311.
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Eyal S, Easterling TR, Carr D, Umans JG, Miodovnik M, Hankins GD, Clark SM, Risler L, Wang J, Kelly EJ, Shen DD, Hebert MF. Pharmacokinetics of metformin during pregnancy. Drug Metab Dispos. 2010 May; 38(5):833-40.