Below are the most recent publications written about "Organoids" by people in Profiles.
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Hansen BC, Arian CM, Zeng Y, Takezawa MG, Theberge AB, Faustman EM, Thummel KE, Kelly EJ. Leveraging RNA-seq deconvolution to improve complex in vitro model characterization. J Biol Chem. 2025 Sep; 301(9):110510.
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O'Mahony ET, Arian CM, Aryeh KS, Wang K, Thummel KE, Kelly EJ. Human intestinal enteroids: Nonclinical applications for predicting oral drug disposition, toxicity, and efficacy. Pharmacol Ther. 2025 Sep; 273:108879.
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Mon-Wei Yu S, Choi JY, Kady J, De Cos M, Wong JS, King E, Younis N, Al Rahy N, Al Chaar S, Djebli H, Eskandari S, Samuel S, Merhej T, Sukumar N, Lin JR, Chen JY, Xu Y, Santagata S, Weins A, Yeung M, Cravedi P, Campbell KN, Lemos D, Bonventre JV, Brehm MA, Azzi J. Transplantation of human kidney organoids elicited a robust allogeneic response in a humanized mouse model. Kidney Int. 2025 Jun; 107(6):1011-1016.
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Marjan T, Lafuente-G?mez N, Rampal A, Mooney DJ, Peyton SR, Qazi TH. Cell-Instructive Biomaterials with Native-Like Biochemical Complexity. Annu Rev Biomed Eng. 2025 05; 27(1):185-209.
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Smith AO, Frantz WT, Preval KM, Edwards YJK, Ceol CJ, Jonassen JA, Pazour GJ. The Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) oncogene is upregulated in cystic epithelial cells revealing a potential new target for polycystic kidney disease. PLoS Genet. 2024 Dec; 20(12):e1011510.
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Dawes P, Barton NJ, Orszulak AR, Chigas SM, Tran K, Sundstrom J, Olson MN, Murray LF, Oh H, Church GM, Knipe DM, Readhead B, Chan Y, Lim ET. Basic Science and Pathogenesis. Alzheimers Dement. 2024 Dec; 20 Suppl 1:e092866.
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Sundstrom J, Vanderleeden E, Barton NJ, Redick SD, Dawes P, Murray LF, Olson MN, Tran K, Chigas SM, Orszulak AR, Church GM, Readhead B, Oh HS, Harlan DM, Knipe DM, Wang JP, Chan Y, Lim ET. Herpes Simplex Virus 1 Infection of Human Brain Organoids and Pancreatic Stem Cell-Islets Drives Organoid-Specific Transcripts Associated with Alzheimer's Disease and Autoimmune Diseases. Cells. 2024 11 29; 13(23).
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Arian C, O'Mahony E, MacDonald JW, Bammler TK, Donowitz M, Kelly EJ, Thummel KE. Human enteroid monolayers: A novel, functionally stable model for investigating oral drug disposition. Drug Metab Dispos. 2025 Jan; 53(1):100002.
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Bozal SB, Sjogren G, Costa AP, Brown JS, Roberts S, Baker D, Gabriel P, Ristau BT, Samuels M, Flynn WF, Robson P, Courtois ET. Development of an automated 3D high content cell screening platform for organoid phenotyping. SLAS Discov. 2024 10; 29(7):100182.
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Okhovatian S, Khosravi R, Wang EY, Zhao Y, Radisic M. Biofabrication strategies for cardiac tissue engineering. Curr Opin Biotechnol. 2024 Aug; 88:103166.