"Anoctamin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An anoctamin chloride channel expressed at high levels in the liver, skeletal muscle, and gastrointestinal muscles that functions in transepithelial anion transport and smooth muscle contraction. It is essential for the function of the INTERSTITIAL CELLS OF CAJAL and plays a major role in chloride conduction by airway epithelial cells and in tracheal cartilage development.
| Descriptor ID |
D000075369
|
| MeSH Number(s) |
D12.776.157.530.400.175.032.500 D12.776.543.550.450.175.032.500 D12.776.543.585.400.175.032.500
|
| Concept/Terms |
Anoctamin-1- Anoctamin-1
- Anoctamin 1
- Transmembrane Protein 16A
- TMEM16A Protein
|
Below are MeSH descriptors whose meaning is more general than "Anoctamin-1".
Below are MeSH descriptors whose meaning is more specific than "Anoctamin-1".
This graph shows the total number of publications written about "Anoctamin-1" by people in this website by year, and whether "Anoctamin-1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2019 | 2 | 0 | 2 |
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Below are the most recent publications written about "Anoctamin-1" by people in Profiles.
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Qu M, Lu P, Bellve K, Fogarty K, Lifshitz L, Shi F, Zhuge R. Smooth muscle cell-specific TMEM16A deletion does not alter Ca2+ signaling, uterine contraction, gestation length, or litter size in mice?. Biol Reprod. 2019 08 01; 101(2):318-327.
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Feng M, Wang Z, Liu Z, Liu D, Zheng K, Lu P, Liu C, Zhang M, Li J. The RyR-ClCa -VDCC axis contributes to spontaneous tone in urethral smooth muscle. J Cell Physiol. 2019 12; 234(12):23256-23267.
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Wang P, Zhao W, Sun J, Tao T, Chen X, Zheng YY, Zhang CH, Chen Z, Gao YQ, She F, Li YQ, Wei LS, Lu P, Chen CP, Zhou J, Wang DQ, Chen L, Shi XH, Deng L, ZhuGe R, Chen HQ, Zhu MS. Inflammatory mediators mediate airway smooth muscle contraction through a G protein-coupled receptor-transmembrane protein 16A-voltage-dependent Ca2+ channel axis and contribute to bronchial hyperresponsiveness in asthma. J Allergy Clin Immunol. 2018 04; 141(4):1259-1268.e11.
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Zhang CH, Wang P, Liu DH, Chen CP, Zhao W, Chen X, Chen C, He WQ, Qiao YN, Tao T, Sun J, Peng YJ, Lu P, Zheng K, Craige SM, Lifshitz LM, Keaney JF, Fogarty KE, ZhuGe R, Zhu MS. The molecular basis of the genesis of basal tone in internal anal sphincter. Nat Commun. 2016 Apr 22; 7:11358.