T-Lymphoma Invasion and Metastasis-inducing Protein 1
"T-Lymphoma Invasion and Metastasis-inducing Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A Rho guanine nucleotide exchange factor that consists of two pleckstrin homology domains flanking central Ras-binding, Dbl-homology (DH) and PDZ domains. It stimulates GTP-GDP exchange of rho-like GTPases such as RAC1 PROTEIN; CDC42 PROTEIN; and RHOA PROTEIN, and functions to link extracellular signals to remodeling of the CYTOSKELETON for CELL ADHESION and CELL MOVEMENT.
| Descriptor ID |
D000075684
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| MeSH Number(s) |
D12.644.360.325.300.850 D12.776.476.325.300.850
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "T-Lymphoma Invasion and Metastasis-inducing Protein 1".
Below are MeSH descriptors whose meaning is more specific than "T-Lymphoma Invasion and Metastasis-inducing Protein 1".
This graph shows the total number of publications written about "T-Lymphoma Invasion and Metastasis-inducing Protein 1" by people in this website by year, and whether "T-Lymphoma Invasion and Metastasis-inducing Protein 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "T-Lymphoma Invasion and Metastasis-inducing Protein 1" by people in Profiles.
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Jecrois AM, Dcona MM, Deng X, Bandyopadhyay D, Grossman SR, Schiffer CA, Royer WE. Cryo-EM structure of CtBP2 confirms tetrameric architecture. Structure. 2021 04 01; 29(4):310-319.e5.
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Saneyoshi T, Matsuno H, Suzuki A, Murakoshi H, Hedrick NG, Agnello E, O'Connell R, Stratton MM, Yasuda R, Hayashi Y. Reciprocal Activation within a Kinase-Effector Complex Underlying Persistence of Structural LTP. Neuron. 2019 06 19; 102(6):1199-1210.e6.
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Moriarty CH, Pursell B, Mercurio AM. miR-10b targets Tiam1: implications for Rac activation and carcinoma migration. J Biol Chem. 2010 Jul 02; 285(27):20541-6.