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Emma Watson PhD

TitleAssistant Professor
InstitutionUMass Chan Medical School
DepartmentSystems Biology
AddressUMass Chan Medical School
368 Plantation Street, AS7-1045
Worcester MA 01605
Phone508-856-6962
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentSystems Biology

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentCancer Biology

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentInterdisciplinary Graduate Program

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentMD/PhD Program

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentSystems Computational and Quantitative Biology


    Collapse Biography 
    Collapse education and training
    University of Connecticut, Storrs, CT, United StatesBSBiophysics
    University of Massachusetts Medical School, Worcester, MA, United StatesPHDBiomedical Science

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Chowdhury SR, Parikh CN, Kaur AN, DeMarco KD, Giwa HK, Mishra AK, Murphy KC, Zhou L, Ma B, Ye T, Li J, Liu H, Bai S, Johnson C, Simin K, Pitarresi JR, Zhu LJ, Watson EV, Kelliher MA, Green MR, Fitzgerald KA, Ruscetti M. PPT1 is a negative regulator of STING signaling in cancer cells and its inhibition reactivates immune surveillance in cold tumors. Proc Natl Acad Sci U S A. 2025 Sep 30; 122(39):e2514948122. PMID: 40982692.
      Citations:    
    2. Bhalerao N, Ogoti Y, Peura J, Johnson C, Chen Q, Korobkina ED, Keller FN, Wengyn M, Norgard RJ, Shamber C, Klute K, DiMaio D, Sellin K, Grandgenett PM, Li R, Hollingsworth MA, Guilherme A, Czech MP, Kremer R, Zhu LJ, Spinelli JB, Watson EV, Ruscetti M, Guertin DA, Pitarresi JR. Pancreatic cancer cachexia is mediated by PTHrP-driven disruption of adipose de novo lipogenesis. bioRxiv. 2025 Aug 20. PMID: 40501563.
      Citations:    
    3. Magesh RY, Kaur AN, Keller FN, Frederick A, Tseyang T, Haley JA, Rivera-Nieves AM, Liang AC, Guertin DA, Spinelli JB, Elledge SJ, Watson EV. Aneuploidy generates enhanced nucleotide dependency and sensitivity to metabolic perturbation. Genes Dev. 2025 Jun 02; 39(11-12):770-786. PMID: 40324880.
      Citations:    
    4. Valeros J, Jerome M, Tseyang T, Vo P, Do T, Fajardo Palomino D, Grotehans N, Kunala M, Jerrett AE, Hathiramani NR, Mireku M, Magesh RY, Yenilmez B, Rosen PC, Mann JL, Myers JW, Kunchok T, Manning TL, Boercker LN, Carr PE, Munim MB, Lewis CA, Sabatini DM, Kelly M, Xie J, Czech MP, Gao G, Shepherd JN, Walker AK, Kim H, Watson EV, Spinelli JB. Rhodoquinone carries electrons in the mammalian electron transport chain. Cell. 2025 Feb 20; 188(4):1084-1099.e27. PMID: 39909039.
      Citations:    
    5. Dowman LJ, Kulkarni SS, Alegre-Requena JV, Giltrap AM, Norman AR, Sharma A, Gallegos LC, Mackay AS, Welegedara AP, Watson EE, van Raad D, Niederacher G, Huhmann S, Proschogo N, Patel K, Larance M, Becker CFW, Mackay JP, Lakhwani G, Huber T, Paton RS, Payne RJ. Site-selective photocatalytic functionalization of peptides and proteins at selenocysteine. Nat Commun. 2022 11 12; 13(1):6885. PMID: 36371402.
      Citations:    
    6. Duggan NM, Saez NJ, Clayton D, Budusan E, Watson EE, Tucker IJ, Rash LD, King GF, Payne RJ. Total Synthesis of the Spider-Venom Peptide Hi1a. Org Lett. 2021 Nov 05; 23(21):8375-8379. PMID: 34632783.
      Citations:    
    7. Agten SM, Watson EE, Ripoll-Rozada J, Dowman LJ, Wu MCL, Alwis I, Jackson SP, Pereira PJB, Payne RJ. Potent Trivalent Inhibitors of Thrombin through Hybridization of Salivary Sulfopeptides from Hematophagous Arthropods. Angew Chem Int Ed Engl. 2021 03 01; 60(10):5348-5356. PMID: 33345438.
      Citations:    
    8. Tran AT, Watson EE, Pujari V, Conroy T, Dowman LJ, Giltrap AM, Pang A, Wong WR, Linington RG, Mahapatra S, Saunders J, Charman SA, West NP, Bugg TD, Tod J, Dowson CG, Roper DI, Crick DC, Britton WJ, Payne RJ. Sansanmycin natural product analogues as potent and selective anti-mycobacterials that inhibit lipid I biosynthesis. Nat Commun. 2017 03 01; 8:14414. PMID: 28248311.
      Citations:    
    9. Watson E, Olin-Sandoval V, Hoy MJ, Li CH, Louisse T, Yao V, Mori A, Holdorf AD, Troyanskaya OG, Ralser M, Walhout AJ. Metabolic network rewiring of propionate flux compensates vitamin B12 deficiency in C. elegans. Elife. 2016 07 06; 5. PMID: 27383050.
      Citations: 48     Fields:    Translation:Animals
    10. Watson E, Yilmaz LS, Walhout AJ. Understanding Metabolic Regulation at a Systems Level: Metabolite Sensing, Mathematical Predictions, and Model Organisms. Annu Rev Genet. 2015; 49:553-75. PMID: 26631516.
      Citations: 20     Fields:    Translation:HumansAnimals
    11. Watson E, Walhout AJ. Caenorhabditis elegans metabolic gene regulatory networks govern the cellular economy. Trends Endocrinol Metab. 2014 Oct; 25(10):502-8. PMID: 24731597.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    12. Watson E, MacNeil LT, Ritter AD, Yilmaz LS, Rosebrock AP, Caudy AA, Walhout AJ. Interspecies systems biology uncovers metabolites affecting C. elegans gene expression and life history traits. Cell. 2014 Feb 13; 156(4):759-70. PMID: 24529378.
      Citations: 96     Fields:    Translation:AnimalsCells
    13. MacNeil LT, Watson E, Arda HE, Zhu LJ, Walhout AJ. Diet-induced developmental acceleration independent of TOR and insulin in C. elegans. Cell. 2013 Mar 28; 153(1):240-52. PMID: 23540701.
      Citations: 148     Fields:    Translation:AnimalsCells
    14. Watson E, MacNeil LT, Arda HE, Zhu LJ, Walhout AJM. Integration of metabolic and gene regulatory networks modulates the C. elegans dietary response. Cell. 2013 Mar 28; 153(1):253-66. PMID: 23540702.
      Citations: 76     Fields:    Translation:HumansAnimalsCells
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