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Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans.
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Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans.
Tissenbaum HA, Guarente L. Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature. 2001 Mar 08; 410(6825):227-30.
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PubMed
subject areas
Animals
Animals, Genetically Modified
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Chromosome Mapping
Female
Forkhead Transcription Factors
Gene Dosage
Gene Duplication
Genes, Fungal
Helminth Proteins
Histone Deacetylases
Longevity
Male
Signal Transduction
Silent Information Regulator Proteins, Saccharomyces cerevisiae
Sirtuin 2
Sirtuins
Trans-Activators
Transcription Factors
authors with profiles
Heidi A Tissenbaum PhD