In the absence of type III receptor, the transforming growth factor (TGF)-beta type II-B receptor requires the type I receptor to bind TGF-beta2.
del Re E, Babitt JL, Pirani A, Schneyer AL, Lin HY. In the absence of type III receptor, the transforming growth factor (TGF)-beta type II-B receptor requires the type I receptor to bind TGF-beta2. J Biol Chem. 2004 May 21; 279(21):22765-72.
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Activin Receptors, Type I
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Animals
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Blotting, Western
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Cell Line
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Cell Membrane
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Cell-Free System
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Cloning, Molecular
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Crystallography, X-Ray
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DNA, Complementary
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Dose-Response Relationship, Drug
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Genes, Reporter
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Glycosylation
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Humans
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Kinetics
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Ligands
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Luciferases
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Mice
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Models, Biological
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Molecular Sequence Data
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Phenotype
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Protein Binding
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Protein Isoforms
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Protein Structure, Tertiary
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Proteoglycans
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Receptors, Transforming Growth Factor beta
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Signal Transduction