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Poxvirus protein N1L targets the I-kappaB kinase complex, inhibits signaling to NF-kappaB by the tumor necrosis factor superfamily of receptors, and inhibits NF-kappaB and IRF3 signaling by toll-like receptors.
CD40 Ligand
Immunology. The shape of things to come.
Heterochromatin assembly: a new twist on an old model.
Inflammasomes and anti-viral immunity.
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Inflammasomes and anti-viral immunity.
Rathinam VA, Fitzgerald KA. Inflammasomes and anti-viral immunity. J Clin Immunol. 2010 Sep; 30(5):632-7.
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PubMed
subject areas
Animals
Caspase 1
DNA, Viral
DNA-Binding Proteins
Enzyme Activation
Humans
Immunity
Inflammasomes
Interferons
Interleukin-18
Interleukin-1beta
Nuclear Proteins
Receptors, Pattern Recognition
RNA, Double-Stranded
Virus Diseases
authors with profiles
Katherine A Fitzgerald PhD