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Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9.
Racial and ethnic differences in hospice use among patients with heart failure.
Spatial partitioning of the regulatory landscape of the X-inactivation centre.
Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction.
Mechanisms of TLR9 activation.
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Mechanisms of TLR9 activation.
Latz E, Visintin A, Espevik T, Golenbock DT. Mechanisms of TLR9 activation. J Endotoxin Res. 2004; 10(6):406-12.
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PubMed
subject areas
Cell Membrane
Cells, Cultured
CpG Islands
DNA, Bacterial
Endoplasmic Reticulum
Escherichia coli
Humans
Leukocytes, Mononuclear
Lysosomes
Membrane Glycoproteins
Microscopy, Confocal
Receptors, Cell Surface
Signal Transduction
Toll-Like Receptor 4
Toll-Like Receptor 9
Toll-Like Receptors
authors with profiles
Douglas T Golenbock MD
Eicke Latz MD