The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion.
Pratap J, Javed A, Languino LR, van Wijnen AJ, Stein JL, Stein GS, Lian JB. The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion. Mol Cell Biol. 2005 Oct; 25(19):8581-91.
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3T3 Cells
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Adenoviridae
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Animals
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Blotting, Western
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Bone Neoplasms
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Cell Line, Tumor
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Cell Nucleus
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Chromatin Immunoprecipitation
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Core Binding Factor Alpha 1 Subunit
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DNA, Complementary
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Gene Expression Regulation, Enzymologic
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HeLa Cells
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Humans
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Matrix Metalloproteinase 9
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Mice
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Mice, Mutant Strains
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Models, Biological
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Models, Genetic
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Neoplasm Invasiveness
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Neoplasm Metastasis
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Osteoblasts
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Promoter Regions, Genetic
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Reverse Transcriptase Polymerase Chain Reaction
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RNA
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RNA Interference
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RNA, Messenger
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RNA, Small Interfering
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Signal Transduction
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Transcriptional Activation