Hypoxia-Ischemia, Brain

"Hypoxia-Ischemia, Brain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A disorder characterized by a reduction of oxygen in the blood combined with reduced blood flow (ISCHEMIA) to the brain from a localized obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ISCHEMIC ATTACK, TRANSIENT; BRAIN INFARCTION; BRAIN EDEMA; COMA; and other conditions.

Descriptor ID	D020925
MeSH Number(s)	C10.228.140.300.150.716 C10.228.140.624.500 C14.907.253.092.716
Concept/Terms	Hypoxia-Ischemia, Brain Hypoxia-Ischemia, Brain Brain Hypoxia-Ischemias Hypoxia Ischemia, Brain Hypoxia-Ischemias, Brain Brain Ischemia-Hypoxia Brain Ischemia Hypoxia Brain Ischemia-Hypoxias Ischemia-Hypoxias, Brain Brain Hypoxia-Ischemia Brain Hypoxia Ischemia Ischemia-Hypoxia, Brain Ischemia Hypoxia, Brain Hypoxic-Ischemic Encephalopathy Hypoxic-Ischemic Encephalopathy Encephalopathies, Hypoxic-Ischemic Hypoxic Ischemic Encephalopathy Hypoxic-Ischemic Encephalopathies Encephalopathy, Hypoxic-Ischemic Encephalopathy, Hypoxic Ischemic Ischemic-Hypoxic Encephalopathy Encephalopathies, Ischemic-Hypoxic Encephalopathy, Ischemic-Hypoxic Ischemic Hypoxic Encephalopathy Ischemic-Hypoxic Encephalopathies Anoxic-Ischemic Encephalopathy Anoxic-Ischemic Encephalopathy Anoxic Ischemic Encephalopathy Anoxic-Ischemic Encephalopathies Encephalopathies, Anoxic-Ischemic Encephalopathy, Anoxic-Ischemic Encephalopathy, Anoxic Ischemic Cerebral Hypoxia-Ischemia Cerebral Hypoxia-Ischemia Cerebral Hypoxia Ischemia Cerebral Hypoxia-Ischemias Hypoxia-Ischemias, Cerebral Hypoxia-Ischemia, Cerebral Hypoxia Ischemia, Cerebral Ischemia-Hypoxia, Cerebral Ischemia Hypoxia, Cerebral Cerebral Ischemia-Hypoxia Cerebral Ischemia Hypoxia Cerebral Ischemia-Hypoxias Ischemia-Hypoxias, Cerebral Anoxia-Ischemia, Brain Anoxia-Ischemia, Brain Anoxia Ischemia, Brain Anoxia-Ischemias, Brain Brain Anoxia-Ischemias Brain Ischemia-Anoxia Brain Ischemia Anoxia Brain Ischemia-Anoxias Ischemia-Anoxias, Brain Brain Anoxia-Ischemia Brain Anoxia Ischemia Ischemia-Anoxia, Brain Ischemia Anoxia, Brain Anoxia-Ischemia, Cerebral Anoxia-Ischemia, Cerebral Anoxia Ischemia, Cerebral Anoxia-Ischemias, Cerebral Cerebral Anoxia-Ischemias Cerebral Anoxia-Ischemia Cerebral Anoxia Ischemia Cerebral Ischemia-Anoxia Cerebral Ischemia Anoxia Cerebral Ischemia-Anoxias Ischemia-Anoxias, Cerebral Ischemia-Anoxia, Cerebral Ischemia Anoxia, Cerebral

Below are MeSH descriptors whose meaning is more general than "Hypoxia-Ischemia, Brain".

Diseases [C]
Nervous System Diseases [C10]
Central Nervous System Diseases [C10.228]
Brain Diseases [C10.228.140]
Cerebrovascular Disorders [C10.228.140.300]
Brain Ischemia [C10.228.140.300.150]
Hypoxia-Ischemia, Brain [C10.228.140.300.150.716]
Hypoxia, Brain [C10.228.140.624]
Hypoxia-Ischemia, Brain [C10.228.140.624.500]
Cardiovascular Diseases [C14]
Vascular Diseases [C14.907]
Cerebrovascular Disorders [C14.907.253]
Brain Ischemia [C14.907.253.092]
Hypoxia-Ischemia, Brain [C14.907.253.092.716]

Below are MeSH descriptors whose meaning is related to "Hypoxia-Ischemia, Brain".

Below are MeSH descriptors whose meaning is more specific than "Hypoxia-Ischemia, Brain".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Hypoxia-Ischemia, Brain" by people in this website by year, and whether "Hypoxia-Ischemia, Brain" was a major or minor topic of these publications.

Bar chart showing 12 publications over 10 distinct years, with a maximum of 2 publications in 2014 and 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2004	1	0	1
2006	1	0	1
2007	1	0	1
2009	1	0	1
2014	2	0	2
2015	2	0	2
2018	1	0	1
2019	1	0	1
2025	0	1	1
2026	1	0	1

Below are the most recent publications written about "Hypoxia-Ischemia, Brain" by people in Profiles.

Bao R, Foster AN, Song Y, Vyas R, Kesri A, Eddine Toubal I, Soltani Kazemi E, Rahmon G, Kucukpinar T, Almansour M, Ho ML, Palaniappan K, Ninalga D, Prasad Koirala C, Mohapatra S, Schlaug G, Wodzinski M, Muller H, Ellis DG, Aizenberg MR, Arda Aydin M, Abdinli E, Unal G, Tahmasebi N, Punithakumar K, Song T, Peng Y, Bates SV, Hirschtick R, Ellen Grant P, Ou Y. BONBID-HIE 2023: Lesion Segmentation Challenge in BOston Neonatal Brain Injury Data for Hypoxic Ischemic Encephalopathy. IEEE Trans Med Imaging. 2026 Apr; 45(4):1711-1725.

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Magro Borigato EV, Scofano Dias BL, Imamura EU, de Oliveira SB, Pires Arci EC, de Carvalho AL, Fernandes da Silva AP?, Pinto Marques FJ, Braga LW. Paralisia cerebral no Brasil: Um estudo multic?ntrico, transversal, e descritivo. Dev Med Child Neurol. 2026 Jul; 68(7):e104-e111.

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Whalen M. A Case Study of Severe Hypercalcemia Secondary to Subcutaneous Fat Necrosis: A Diagnosis of Exclusion. Neonatal Netw. 2019 Jul 01; 38(4):236-241.

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Salas J, Reddy N, Orru E, Carson KA, Chavez-Valdez R, Burton VJ, Stafstrom CE, Northington FJ, Huisman TAGM. The Role of Diffusion Tensor Imaging in Detecting Hippocampal Injury Following Neonatal Hypoxic-Ischemic Encephalopathy. J Neuroimaging. 2019 03; 29(2):252-259.

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Arca-D?az G, Re TJ, Drottar M, Fortuno CR, De Macedo-Rodrigues K, Im K, Figueras-Aloy J, Grant PE. Can cerebellar and brainstem apparent diffusion coefficient (ADC) values predict neuromotor outcome in term neonates with hypoxic-ischemic encephalopathy (HIE) treated with hypothermia? PLoS One. 2017; 12(7):e0178510.

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Roberts JK, Stockmann C, Ward RM, Beachy J, Baserga MC, Spigarelli MG, Sherwin CM. Population Pharmacokinetics of Darbepoetin Alfa in Conjunction with Hypothermia for the Treatment of Neonatal Hypoxic-Ischemic Encephalopathy. Clin Pharmacokinet. 2015 Dec; 54(12):1237-44.

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Ystgaard MB, Sejersted Y, L?berg EM, Lien E, Yndestad A, Saugstad OD. Early Upregulation of NLRP3 in the Brain of Neonatal Mice Exposed to Hypoxia-Ischemia: No Early Neuroprotective Effects of NLRP3 Deficiency. Neonatology. 2015; 108(3):211-9.

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Lin EP, Miles L, Hughes EA, McCann JC, Vorhees CV, McAuliffe JJ, Loepke AW. A combination of mild hypothermia and sevoflurane affords long-term protection in a modified neonatal mouse model of cerebral hypoxia-ischemia. Anesth Analg. 2014 Nov; 119(5):1158-73.

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Lange S, Rocha-Ferreira E, Thei L, Mawjee P, Bennett K, Thompson PR, Subramanian V, Nicholas AP, Peebles D, Hristova M, Raivich G. Peptidylarginine deiminases: novel drug targets for prevention of neuronal damage following hypoxic ischemic insult (HI) in neonates. J Neurochem. 2014 Aug; 130(4):555-62.

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Kurth CD, McCann JC, Wu J, Miles L, Loepke AW. Cerebral oxygen saturation-time threshold for hypoxic-ischemic injury in piglets. Anesth Analg. 2009 Apr; 108(4):1268-77.

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