Receptors, Leptin

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"Receptors, Leptin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Cell surface receptors for obesity factor (LEPTIN), a hormone secreted by the WHITE ADIPOCYTES. Upon leptin-receptor interaction, the signal is mediated through the JAK2/STAT3 pathway to regulate food intake, energy balance and fat storage.

Descriptor ID	D054411
MeSH Number(s)	D12.776.543.750.650.500
Concept/Terms	Receptors, Leptin Receptors, Leptin Leptin-Binding Protein Leptin Binding Protein Receptor, Leptin Leptin Receptor Antigens, CD295 LEPR Protein OB Receptor Receptor, OB CD295 Antigens Leptin Receptors OBRa Receptor OBRa Receptor Receptor, OBRa OBRb Receptor OBRb Receptor Receptor, OBRb Leptin Receptor, Large Isoform Leptin Receptor, Small Isoform Leptin Receptor, Small Isoform

Below are MeSH descriptors whose meaning is more general than "Receptors, Leptin".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, Adipokine [D12.776.543.750.650]
Receptors, Leptin [D12.776.543.750.650.500]

Below are MeSH descriptors whose meaning is related to "Receptors, Leptin".

Below are MeSH descriptors whose meaning is more specific than "Receptors, Leptin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptors, Leptin" by people in this website by year, and whether "Receptors, Leptin" was a major or minor topic of these publications.

Bar chart showing 12 publications over 9 distinct years, with a maximum of 2 publications in 2003 and 2006 and 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2003	0	2	2
2005	0	1	1
2006	0	2	2
2009	0	1	1
2014	1	0	1
2015	0	1	1
2018	0	2	2
2021	1	0	1
2026	0	1	1

Below are the most recent publications written about "Receptors, Leptin" by people in Profiles.

Yokoi N, Shigenaka S, Nakata C, Takagi M, Xiao Y, Hirokoji T, Sasase T, Uno K, Ohta T. Effects of sex hormones on the development of diabetes and pancreatic islet gene expression in obese type 2 diabetes model ZFDM rat. Exp Anim. 2026 Jul 01; 75(3):262-276.

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Duquenne M, Folgueira C, Bourouh C, Millet M, Silva A, Clasadonte J, Imbernon M, Fernandois D, Martinez-Corral I, Kusumakshi S, Caron E, Rasika S, Deliglia E, Jouy N, Oishi A, Mazzone M, Trinquet E, Tavernier J, Kim YB, Ory S, Jockers R, Schwaninger M, Boehm U, Nogueiras R, Annicotte JS, Gasman S, Dam J, Pr?vot V. Leptin brain entry via a tanycytic LepR-EGFR shuttle controls lipid metabolism and pancreas function. Nat Metab. 2021 08; 3(8):1071-1090.

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Olea-Flores M, Ju?rez-Cruz JC, Mendoza-Catal?n MA, Padilla-Benavides T, Navarro-Tito N. Signaling Pathways Induced by Leptin during Epithelial?Mesenchymal Transition in Breast Cancer. Int J Mol Sci. 2018 Nov 06; 19(11).

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Hayes KL, Messina LM, Schwartz LM, Yan J, Burnside AS, Witkowski S. Type 2 diabetes impairs the ability of skeletal muscle pericytes to augment postischemic neovascularization in db/db mice. Am J Physiol Cell Physiol. 2018 05 01; 314(5):C534-C544.

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Zachariah JP, Quiroz R, Enserro D, Andersson C, Keaney JF, Sullivan LM, Vasan RS. Association of Parental Obesity and Diabetes Mellitus With Circulating Adipokines in Nonobese Nondiabetic Offspring. J Am Heart Assoc. 2017 Jul 16; 6(7).

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Zachariah JP, Quiroz R, Nelson KP, Teng Z, Keaney JF, Sullivan LM, Vasan RS. Prospective Relation of Circulating Adipokines to Incident Metabolic Syndrome: The Framingham Heart Study. J Am Heart Assoc. 2017 Jul 16; 6(7).

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Lee JJ, Britton KA, Pedley A, Massaro JM, Speliotes EK, Murabito JM, Hoffmann U, Ingram C, Keaney JF, Vasan RS, Fox CS. Adipose Tissue Depots and Their Cross-Sectional Associations With Circulating Biomarkers of Metabolic Regulation. J Am Heart Assoc. 2016 05 04; 5(5).

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Sharma RB, O'Donnell AC, Stamateris RE, Ha B, McCloskey KM, Reynolds PR, Arvan P, Alonso LC. Insulin demand regulates ? cell number via the unfolded protein response. J Clin Invest. 2015 Oct 01; 125(10):3831-46.

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Chang CC, Wu MJ, Yang JY, Camarillo IG, Chang CJ. Leptin-STAT3-G9a Signaling Promotes Obesity-Mediated Breast Cancer Progression. Cancer Res. 2015 Jun 01; 75(11):2375-2386.

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Martin C, Navarro VM, Simavli S, Vong L, Carroll RS, Lowell BB, Kaiser UB. Leptin-responsive GABAergic neurons regulate fertility through pathways that result in reduced kisspeptinergic tone. J Neurosci. 2014 Apr 23; 34(17):6047-56.

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