"Amitriptyline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
Descriptor ID |
D000639
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MeSH Number(s) |
D02.455.426.559.847.181.384.100 D04.615.181.384.100
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Amitriptyline".
Below are MeSH descriptors whose meaning is more specific than "Amitriptyline".
This graph shows the total number of publications written about "Amitriptyline" by people in this website by year, and whether "Amitriptyline" was a major or minor topic of these publications.
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click here.
Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 1 | 1 |
2004 | 1 | 0 | 1 |
2006 | 0 | 2 | 2 |
2010 | 0 | 1 | 1 |
2012 | 0 | 1 | 1 |
2015 | 0 | 1 | 1 |
2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Amitriptyline" by people in Profiles.
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Stock EM, Zeber JE, McNeal CJ, Banchs JE, Copeland LA. Psychotropic Pharmacotherapy Associated With QT Prolongation Among Veterans With Posttraumatic Stress Disorder. Ann Pharmacother. 2018 09; 52(9):838-848.
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Felton D, Zitomersky N, Manzi S, Lightdale JR. 13-year-old girl with recurrent, episodic, persistent vomiting: out of the pot and into the fire. Pediatrics. 2015 Apr; 135(4):e1060-3.
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Hershman DL, Lacchetti C, Dworkin RH, Lavoie Smith EM, Bleeker J, Cavaletti G, Chauhan C, Gavin P, Lavino A, Lustberg MB, Paice J, Schneider B, Smith ML, Smith T, Terstriep S, Wagner-Johnston N, Bak K, Loprinzi CL. Prevention and management of chemotherapy-induced peripheral neuropathy in survivors of adult cancers: American Society of Clinical Oncology clinical practice guideline. J Clin Oncol. 2014 Jun 20; 32(18):1941-67.
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Mohammad S, Di Lorenzo C, Youssef NN, Miranda A, Nurko S, Hyman P, Saps M. Assessment of abdominal pain through global outcomes and recent FDA recommendations in children: are we ready for change? J Pediatr Gastroenterol Nutr. 2014 Jan; 58(1):46-50.
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Chogle A, Sztainberg M, Bass L, Youssef NN, Miranda A, Nurko S, Hyman P, Cocjin J, Di Lorenzo C, Saps M. Accuracy of pain recall in children. J Pediatr Gastroenterol Nutr. 2012 Sep; 55(3):288-91.
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Shenoy AM. Guidelines in practice: treatment of painful diabetic neuropathy. Continuum (Minneap Minn). 2012 Feb; 18(1):192-8.
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Irwin RS. Unexplained cough in the adult. Otolaryngol Clin North Am. 2010 Feb; 43(1):167-80, xi-xii.
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Saps M, Youssef N, Miranda A, Nurko S, Hyman P, Cocjin J, Di Lorenzo C. Multicenter, randomized, placebo-controlled trial of amitriptyline in children with functional gastrointestinal disorders. Gastroenterology. 2009 Oct; 137(4):1261-9.
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Wu EQ, Birnbaum HG, Mareva MN, Le TK, Robinson RL, Rosen A, Gelwicks S. Cost-effectiveness of duloxetine versus routine treatment for U.S. patients with diabetic peripheral neuropathic pain. J Pain. 2006 Jun; 7(6):399-407.
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Allen LaPointe NM, Curtis LH, Chan KA, Kramer JM, Lafata JE, Gurwitz JH, Raebel MA, Platt R. Frequency of high-risk use of QT-prolonging medications. Pharmacoepidemiol Drug Saf. 2006 Jun; 15(6):361-8.