"Photobleaching" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Light-induced change in a chromophore, resulting in the loss of its absorption of light of a particular wave length. The photon energy causes a conformational change in the photoreceptor proteins affecting PHOTOTRANSDUCTION. This occurs naturally in the retina (ADAPTATION, OCULAR) on long exposure to bright light. Photobleaching presents problems when occurring in PHOTODYNAMIC THERAPY, and in FLUORESCENCE MICROSCOPY. On the other hand, this phenomenon is exploited in the technique, FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING, allowing measurement of the movements of proteins and LIPIDS in the CELL MEMBRANE.
| Descriptor ID |
D038761
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| MeSH Number(s) |
G02.740.680
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Photobleaching".
Below are MeSH descriptors whose meaning is more specific than "Photobleaching".
This graph shows the total number of publications written about "Photobleaching" by people in this website by year, and whether "Photobleaching" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Photobleaching" by people in Profiles.
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Wolakiewicz G, Pietrzak M, Szabelski M. Silver Nanoparticles Improve Fluorophore Photostability: Application to a Hypericin Study. Int J Mol Sci. 2024 Sep 15; 25(18).
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Robinson A, Partridge D, Malhas A, De Castro SC, Gustavsson P, Thompson DN, Vaux DJ, Copp AJ, Stanier P, Bassuk AG, Greene ND. Is LMNB1 a susceptibility gene for neural tube defects in humans? Birth Defects Res A Clin Mol Teratol. 2013 Jun; 97(6):398-402.
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Dave R, Terry DS, Munro JB, Blanchard SC. Mitigating unwanted photophysical processes for improved single-molecule fluorescence imaging. Biophys J. 2009 Mar 18; 96(6):2371-81.
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Kirber MT, Chen K, Keaney JF. YFP photoconversion revisited: confirmation of the CFP-like species. Nat Methods. 2007 Oct; 4(10):767-8.
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Tulu US, Rusan NM, Wadsworth P. Peripheral, non-centrosome-associated microtubules contribute to spindle formation in centrosome-containing cells. Curr Biol. 2003 Oct 28; 13(21):1894-9.