"Valinomycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cyclododecadepsipeptide ionophore antibiotic produced by Streptomyces fulvissimus and related to the enniatins. It is composed of 3 moles each of L-valine, D-alpha-hydroxyisovaleric acid, D-valine, and L-lactic acid linked alternately to form a 36-membered ring. (From Merck Index, 11th ed) Valinomycin is a potassium selective ionophore and is commonly used as a tool in biochemical studies.
| Descriptor ID |
D014634
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| MeSH Number(s) |
D04.345.566.297.500 D12.644.641.297.500
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Valinomycin".
Below are MeSH descriptors whose meaning is more specific than "Valinomycin".
This graph shows the total number of publications written about "Valinomycin" by people in this website by year, and whether "Valinomycin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
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Below are the most recent publications written about "Valinomycin" by people in Profiles.
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Demarco IA, Espinosa F, Edwards J, Sosnik J, De La Vega-Beltran JL, Hockensmith JW, Kopf GS, Darszon A, Visconti PE. Involvement of a Na+/HCO-3 cotransporter in mouse sperm capacitation. J Biol Chem. 2003 Feb 28; 278(9):7001-9.
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Park CS, Honeyman TW, Ha SK, Choi HK, Chung CL, Hong CD. Mechanisms of ionophore-induced stimulation of renin secretion with special reference to a chemiosmotic hypothesis. J Pharmacol Exp Ther. 1991 Oct; 259(1):211-8.
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Styrt B, Klempner MS. Internal pH of human neutrophil lysosomes. FEBS Lett. 1982 Nov 22; 149(1):113-6.
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Haveman J, Lavorel J. Identification of the 120 mus phase in the decay of delayed fluorescence in spinach chloroplasts and subchloroplast particles as the intrinsic back reaction. The dependence of the level of this phase on the thylakoids internal pH. Biochim Biophys Acta. 1975 Dec 11; 408(3):269-38.