Research Design

"Research Design" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A plan for collecting and utilizing data so that desired information can be obtained with sufficient precision or so that an hypothesis can be tested properly.

Descriptor ID	D012107
MeSH Number(s)	E05.581.500 H01.770.644.728
Concept/Terms	Research Design Research Design Design, Research Designs, Research Research Designs Research Strategy Research Strategy Research Strategies Strategies, Research Strategy, Research Error Sources Error Sources Error Source Source, Error Sources, Error Data Reporting Data Reporting Reporting, Data Scoring Methods Scoring Methods Method, Scoring Methods, Scoring Scoring Method Matched Groups Matched Groups Group, Matched Groups, Matched Matched Group Research Techniques Research Techniques Research Technique Technique, Research Techniques, Research Research Technics Research Technic Technic, Research Technics, Research Research Methodology Research Methodology Methodology, Research Research Proposal Research Proposal Proposal, Research Proposals, Research Research Proposals Data Adjustment Data Adjustment Adjustment, Data Adjustments, Data Data Adjustments Problem Formulation Problem Formulation Formulation, Problem Formulations, Problem Problem Formulations Experimental Design Experimental Design Experimental Designs Design, Experimental Designs, Experimental

Below are MeSH descriptors whose meaning is more general than "Research Design".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Methods [E05.581]
Research Design [E05.581.500]
Natural Sciences [H]
Natural Science Disciplines [H01]
Science [H01.770]
Research [H01.770.644]
Research Design [H01.770.644.728]

Below are MeSH descriptors whose meaning is more specific than "Research Design".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Research Design" by people in this website by year, and whether "Research Design" was a major or minor topic of these publications.

Bar chart showing 436 publications over 31 distinct years, with a maximum of 28 publications in 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	6	7
1997	1	3	4
1998	0	5	5
1999	1	3	4
2000	0	1	1
2001	1	2	3
2002	2	4	6
2003	4	5	9
2004	2	12	14
2005	6	13	19
2006	5	11	16
2007	8	9	17
2008	5	11	16
2009	1	13	14
2010	7	15	22
2011	5	21	26
2012	6	18	24
2013	11	14	25
2014	6	8	14
2015	6	13	19
2016	9	12	21
2017	8	13	21
2018	10	18	28
2019	3	15	18
2020	8	13	21
2021	4	15	19
2022	3	4	7
2023	6	10	16
2024	1	8	9
2025	2	5	7
2026	1	3	4

Below are the most recent publications written about "Research Design" by people in Profiles.

Xiang Y, Yang S, Guo L, Dong C, Majoie CBLM, Siddiqui AH, Mocco J, Cavalcante F, Li BH, Wang JH, Huang B, Wang DZ, Yu NW, Schonewille WJ, Turk AS, Guo FQ. BEST-BAO: a multicentre, prospective, randomised controlled trial of endovascular treatment with or without intravenous thrombolysis in acute ischaemic stroke due to basilar artery occlusion - study protocol and rationale. Stroke Vasc Neurol. 2026 Jun 29; 11(3):358-364.

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Pastier C, Sylla P, Lee SW, Spinelli A, Komen N, Marks J, Martz J, Rhee R, Maykel J, Marcet J, Denost Q, Zaghiyan K, Davids JS, Paluvoi N, Hiller D, McLemore EC, Maggiori L, D'hoore A, Jafari MD, Poylin V, Buzas CJ, Tuech JJ, Lef?vre JH. Safety and effectiveness of the Colovac anastomosis protection device compared with diverting ileostomy after low anterior resection: protocol for an international, multicentre, prospective, non-randomised comparative study (SAFE-3). BMJ Open Gastroenterol. 2026 Jun 12; 13(1).

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Davidson CJ, Hahn RT, Mehaffey JH, Cohen DJ, Pinney SP, Arnold SV, Stolz L, Lawlor MK, Lindenfeld J, Brener MI, Afzal AM, Smith RL, White RM, Vemulapalli S, Alu MC, Cohen E, Regan K, Sannino A, Elmariah S, Spitzer E, Blackstone EH, Lurz P, Lindman BR, Topilsky Y, Baron SJ, Chadderdon S, Khalique OK, Tang GHL, Taramasso M, Grayburn PA, Badano L, Leipsic J, Windecker S, Redfors B, Rod?s-Cabau J, Ben-Yehuda O, Ailawadi G, Mack MJ, Leon MB, Badhwar V, Hausleiter J. Tricuspid Valve Academic Research Consortium-2 (TVARC-2): Trial Design and Endpoints J Am Coll Cardiol. 2026 Apr 21; 87(15):2044-2070.

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Kim MJ, Yoo SH, Woo KS, Choi H, Chang E, Choi K, Park YS, Kim Y, Kim DH, Kim J, Shin DW. Toward the Implementation of Shared Decision-Making in Korean Clinical Practice: Study Protocol for a Foundational Research Project. J Korean Med Sci. 2026 Jan 26; 41(4):e38.

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Jin Y, Yan S, Yao X, Dahm P, Alonso-Coello P, Brignardello-Petersen R, Keitz S, Rylance J, Cheung M, Agoritsas T, Kunkle R, Murad MH, Guyatt G. Study protocol for developing the evaluation instrument of guideline adherence to GRADE approach (GRADE-Check). BMJ Open. 2025 Nov 09; 15(11):e105534.

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Hayes KN, Niznik JD, Gnjidic D, Moriarty F, Bennett D, Laroche ML, Talbot D, Alcusky M, Sessa M, Coe AB, Sirois C, Zullo AR, Li X, Chalasani SH, Syed J, Sawan M, Moga DC. The Reporting and Methodological Recommendations for Observational Studies Estimating the Effects of Deprescribing Medications (REMROSE-D) ISPE-Endorsed Guidance. Pharmacoepidemiol Drug Saf. 2025 11; 34(11):e70255.

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Diaz LA, Thiele M, Louvet A, Lee BP, Ajmera V, Tavaglione F, Hsu CL, Huang DQ, Pose E, Bataller R, McClain C, Mellinger J, Tincopa M, Mitchell MC, Ratziu V, Rinella ME, Sarin SK, Shah VH, Szabo G, Wong VW, Bansal MB, Leggio L, Kamath PS, Krag A, Sanyal AJ, Arrese M, Arab JP, Anstee QM, Mathurin P, Loomba R. Clinical trial design, biomarkers and end points in metabolic and alcohol-related liver disease. Nat Rev Gastroenterol Hepatol. 2025 Dec; 22(12):866-884.

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Anderson ML, Wilkins AM, Hostovsky S, Pici-D'Ottavio E, Aldalur A, McGinnis F, Meza K. Psychotherapy research in the deaf community: pilot clinical trial lessons learned. J Deaf Stud Deaf Educ. 2025 Jun 20; 30(3):315-323.

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P?rez CM, Kiefe CI, Person SD, Tucker KL, Torres P, Sandoval E, Boneu C, Ram?rez Z, Mattei J, Rodr?guez-Orengo J, Almod?var-Rivera I, Rosal MC. The Puerto Rico Young Adults' Stress, Contextual, Behavioral, and Cardiometabolic Risk (PR-OUTLOOK) Study: design and methods. Am J Epidemiol. 2025 03 04; 194(3):587-597.

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Charlson ME, Mittleman I, Ramos R, Cassells A, Lin TJ, Eggleston A, Wells MT, Hollenberg J, Pirraglia P, Winston G, Tobin JN. Preventing "tipping points" in high comorbidity patients: A lifeline from health coaches - rationale, design and methods. Contemp Clin Trials. 2025 05; 152:107865.

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