L-Selectin

"L-Selectin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Cell adhesion molecule and CD antigen that serves as a homing receptor for lymphocytes to lymph node high endothelial venules.

Descriptor ID	D019041
MeSH Number(s)	D12.776.395.550.200.625.903 D12.776.395.550.200.700.510 D12.776.503.843.510 D12.776.543.550.200.625.903 D12.776.543.550.200.700.510 D12.776.543.750.705.877.903 D23.050.301.350.625.903 D23.050.301.350.700.510
Concept/Terms	L-Selectin L-Selectin Mel-14 Antigen Antigen, Mel-14 Mel 14 Antigen L Selectin Selectin, L LAM-1 CD62L Antigens Leu-8 Antigen Antigen, Leu-8 Leu 8 Antigen TQ1 Antigen Antigen, TQ1 CD62L Antigen Antigen, CD62L Antigens, CD62L Leukocyte Adhesion Molecule, LAM-1 Leukocyte Adhesion Molecule, LAM 1 LECAM-1

Below are MeSH descriptors whose meaning is more general than "L-Selectin".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Glycoproteins [D12.776.395]
Membrane Glycoproteins [D12.776.395.550]
Cell Adhesion Molecules [D12.776.395.550.200]
Receptors, Lymphocyte Homing [D12.776.395.550.200.625]
L-Selectin [D12.776.395.550.200.625.903]
Selectins [D12.776.395.550.200.700]
L-Selectin [D12.776.395.550.200.700.510]
Lectins [D12.776.503]
Selectins [D12.776.503.843]
L-Selectin [D12.776.503.843.510]
Membrane Proteins [D12.776.543]
Membrane Glycoproteins [D12.776.543.550]
Cell Adhesion Molecules [D12.776.543.550.200]
Receptors, Lymphocyte Homing [D12.776.543.550.200.625]
L-Selectin [D12.776.543.550.200.625.903]
Selectins [D12.776.543.550.200.700]
L-Selectin [D12.776.543.550.200.700.510]
Receptors, Cell Surface [D12.776.543.750]
Receptors, Immunologic [D12.776.543.750.705]
Receptors, Lymphocyte Homing [D12.776.543.750.705.877]
L-Selectin [D12.776.543.750.705.877.903]
Biological Factors [D23]
Antigens [D23.050]
Antigens, Surface [D23.050.301]
Cell Adhesion Molecules [D23.050.301.350]
Receptors, Lymphocyte Homing [D23.050.301.350.625]
L-Selectin [D23.050.301.350.625.903]
Selectins [D23.050.301.350.700]
L-Selectin [D23.050.301.350.700.510]

Below are MeSH descriptors whose meaning is related to "L-Selectin".

Below are MeSH descriptors whose meaning is more specific than "L-Selectin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "L-Selectin" by people in this website by year, and whether "L-Selectin" was a major or minor topic of these publications.

Bar chart showing 13 publications over 11 distinct years, with a maximum of 2 publications in 2004 and 2007

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	1	0	1
1999	0	1	1
2002	0	1	1
2003	1	0	1
2004	0	2	2
2005	1	0	1
2006	0	1	1
2007	1	1	2
2011	0	1	1
2014	0	1	1
2016	0	1	1

Below are the most recent publications written about "L-Selectin" by people in Profiles.

Pach?n-Pe?a G, Donnelly C, Ruiz-Ca?ada C, Katz A, Fern?ndez-Veledo S, Vendrell J, Sackstein R. A Glycovariant of Human CD44 is Characteristically Expressed on Human Mesenchymal Stem Cells. Stem Cells. 2017 04; 35(4):1080-1092.

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Mace TA, Shakya R, Pitarresi JR, Swanson B, McQuinn CW, Loftus S, Nordquist E, Cruz-Monserrate Z, Yu L, Young G, Zhong X, Zimmers TA, Ostrowski MC, Ludwig T, Bloomston M, Bekaii-Saab T, Lesinski GB. IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer. Gut. 2018 02; 67(2):320-332.

View in: PubMed
Knight JS, Luo W, O'Dell AA, Yalavarthi S, Zhao W, Subramanian V, Guo C, Grenn RC, Thompson PR, Eitzman DT, Kaplan MJ. Peptidylarginine deiminase inhibition reduces vascular damage and modulates innate immune responses in murine models of atherosclerosis. Circ Res. 2014 Mar 14; 114(6):947-56.

View in: PubMed
Gaudreault N, Kumar N, Posada JM, Stephens KB, Reyes de Mochel NS, Eberl? D, Olivas VR, Kim RY, Harms MJ, Johnson S, Messina LM, Rapp JH, Raffai RL. ApoE suppresses atherosclerosis by reducing lipid accumulation in circulating monocytes and the expression of inflammatory molecules on monocytes and vascular endothelium. Arterioscler Thromb Vasc Biol. 2012 Feb; 32(2):264-72.

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McKinstry KK, Golech S, Lee WH, Huston G, Weng NP, Swain SL. Rapid default transition of CD4 T cell effectors to functional memory cells. J Exp Med. 2007 Sep 03; 204(9):2199-211.

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Ahmad I, Hoessli DC, Gupta R, Walker-Nasir E, Rafik SM, Choudhary MI, Shakoori AR. In silico determination of intracellular glycosylation and phosphorylation sites in human selectins: implications for biological function. J Cell Biochem. 2007 Apr 15; 100(6):1558-72.

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Mitoma J, Bao X, Petryanik B, Schaerli P, Gauguet JM, Yu SY, Kawashima H, Saito H, Ohtsubo K, Marth JD, Khoo KH, von Andrian UH, Lowe JB, Fukuda M. Critical functions of N-glycans in L-selectin-mediated lymphocyte homing and recruitment. Nat Immunol. 2007 Apr; 8(4):409-18.

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Kamath A, Woodworth JS, Behar SM. Antigen-specific CD8+ T cells and the development of central memory during Mycobacterium tuberculosis infection. J Immunol. 2006 Nov 01; 177(9):6361-9.

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Uchimura K, Gauguet JM, Singer MS, Tsay D, Kannagi R, Muramatsu T, von Andrian UH, Rosen SD. A major class of L-selectin ligands is eliminated in mice deficient in two sulfotransferases expressed in high endothelial venules. Nat Immunol. 2005 Nov; 6(11):1105-13.

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Lyadova IV, Oberdorf S, Kapina MA, Apt AS, Swain SL, Sayles PC. CD4 T cells producing IFN-gamma in the lungs of mice challenged with mycobacteria express a CD27-negative phenotype. Clin Exp Immunol. 2004 Oct; 138(1):21-9.

View in: PubMed

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