"Chlorpromazine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
| Descriptor ID |
D002746
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| MeSH Number(s) |
D02.886.369.198 D03.633.300.741.198
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Chlorpromazine".
Below are MeSH descriptors whose meaning is more specific than "Chlorpromazine".
This graph shows the total number of publications written about "Chlorpromazine" by people in this website by year, and whether "Chlorpromazine" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
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Below are the most recent publications written about "Chlorpromazine" by people in Profiles.
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de Leon J, Correa JC, Rua?o G, Windemuth A, Arranz MJ, Diaz FJ. Exploring genetic variations that may be associated with the direct effects of some antipsychotics on lipid levels. Schizophr Res. 2008 Jan; 98(1-3):40-6.
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Niznikiewicz MA, Patel JK, McCarley R, Sutton J, Chau DT, Wojcik J, Green AI. Clozapine action on auditory P3 response in schizophrenia. Schizophr Res. 2005 Jul 01; 76(1):119-21.
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Baum S, Ashok A, Gee G, Dimitrova S, Querbes W, Jordan J, Atwood WJ. Early events in the life cycle of JC virus as potential therapeutic targets for the treatment of progressive multifocal leukoencephalopathy. J Neurovirol. 2003; 9 Suppl 1:32-7.
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Howanitz E, Pardo M, Smelson DA, Engelhart C, Eisenstein N, Stern RG, Losonczy MF. The efficacy and safety of clozapine versus chlorpromazine in geriatric schizophrenia. J Clin Psychiatry. 1999 Jan; 60(1):41-4.
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Witman GB, Minervini N. Role of calmodulin in the flagellar axoneme: effect of phenothiazines on reactivated axonemes of Chlamydomonas. Prog Clin Biol Res. 1982; 80:199-204.
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Woda BA, Yguerabide J, Feldman JD. The effect of local anesthetics on the lateral mobility of lymphocyte membrane proteins. Exp Cell Res. 1980 Apr; 126(2):327-31.
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Gardos G, Cole JO. Maintenance antipsychotic therapy: is the cure worse than the disease? Am J Psychiatry. 1976 Jan; 133(1):32-6.
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McKenzie GM, Sadof M. Effect of morphine and chlorpromazine on apomorphine-induced stereotyped behavior. J Pharm Pharmacol. 1974 Apr; 26(4):280-2.