"Giant Cell Tumor of Bone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A bone tumor composed of cellular spindle-cell stroma containing scattered multinucleated giant cells resembling osteoclasts. The tumors range from benign to frankly malignant lesions. The tumor occurs most frequently in an end of a long tubular bone in young adults. (From Dorland, 27th ed; Stedman, 25th ed)
| Descriptor ID |
D018212
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| MeSH Number(s) |
C04.557.450.565.380.380 C04.557.450.565.575.420
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Giant Cell Tumor of Bone".
Below are MeSH descriptors whose meaning is more specific than "Giant Cell Tumor of Bone".
This graph shows the total number of publications written about "Giant Cell Tumor of Bone" by people in this website by year, and whether "Giant Cell Tumor of Bone" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 2 | 0 | 2 |
| 2010 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Giant Cell Tumor of Bone" by people in Profiles.
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DeFazio MW, Selove W, Watts G, Harchandani S, Sood R, Lou F, Most MJ. Recurrent Giant Cell Tumor of Bone with New Pulmonary Metastases 9 Years After En Bloc Distal Radius Resection: A Case Report. JBJS Case Connect. 2023 07 01; 13(3).
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Toledo RA, Qin Y, Cheng ZM, Gao Q, Iwata S, Silva GM, Prasad ML, Ocal IT, Rao S, Aronin N, Barontini M, Bruder J, Reddick RL, Chen Y, Aguiar RC, Dahia PL. Recurrent Mutations of Chromatin-Remodeling Genes and Kinase Receptors in Pheochromocytomas and Paragangliomas. Clin Cancer Res. 2016 05 01; 22(9):2301-10.
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Puri A, Gulia A, Agarwal MG, Reddy K. Ulnar translocation after excision of a Campanacci grade-3 giant-cell tumour of the distal radius: an effective method of reconstruction. J Bone Joint Surg Br. 2010 Jun; 92(6):875-9.
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Baker SB, Parikh PM, Rhodes DN, Abu-Ghosh A, Shad AT. Aggressive central giant cell lesion of the maxilla: surgical management and the use of adjuvant interferon alfa-2a. Plast Reconstr Surg. 2008 Aug; 122(2):77e-79e.
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Gupta R, Seethalakshmi V, Jambhekar NA, Prabhudesai S, Merchant N, Puri A, Agarwal M. Clinicopathologic profile of 470 giant cell tumors of bone from a cancer hospital in western India. Ann Diagn Pathol. 2008 Aug; 12(4):239-248.
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Gravallese EM, Manning C, Tsay A, Naito A, Pan C, Amento E, Goldring SR. Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factor. Arthritis Rheum. 2000 Feb; 43(2):250-8.