Osteosarcoma

"Osteosarcoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)

Descriptor ID	D012516
MeSH Number(s)	C04.557.450.565.575.650 C04.557.450.795.620
Concept/Terms	Osteosarcoma Osteosarcoma Osteosarcomas Osteosarcoma Tumor Osteosarcoma Tumors Tumor, Osteosarcoma Tumors, Osteosarcoma Sarcoma, Osteogenic Osteogenic Sarcomas Sarcomas, Osteogenic Osteogenic Sarcoma

Below are MeSH descriptors whose meaning is more general than "Osteosarcoma".

Diseases [C]
Neoplasms [C04]
Neoplasms by Histologic Type [C04.557]
Neoplasms, Connective and Soft Tissue [C04.557.450]
Neoplasms, Connective Tissue [C04.557.450.565]
Neoplasms, Bone Tissue [C04.557.450.565.575]
Osteosarcoma [C04.557.450.565.575.650]
Sarcoma [C04.557.450.795]
Osteosarcoma [C04.557.450.795.620]

Below are MeSH descriptors whose meaning is more specific than "Osteosarcoma".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Osteosarcoma" by people in this website by year, and whether "Osteosarcoma" was a major or minor topic of these publications.

Bar chart showing 41 publications over 21 distinct years, with a maximum of 3 publications in 2002 and 2010 and 2012 and 2013 and 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	1	2	3
2003	0	2	2
2005	0	2	2
2006	1	1	2
2007	0	2	2
2008	2	0	2
2009	1	0	1
2010	2	1	3
2011	2	0	2
2012	3	0	3
2013	2	1	3
2014	0	1	1
2015	1	1	2
2016	3	0	3
2017	2	0	2
2018	0	1	1
2019	2	0	2
2020	1	0	1
2022	2	0	2
2024	0	1	1
2025	1	0	1

Below are the most recent publications written about "Osteosarcoma" by people in Profiles.

Husted C, Adrianowycz S, Peterson C, DeWitt SB, Karlsson EK, Eward W, Somarelli JA, Megquier K, Gardner HL. Characterization of the genomic landscape of canine oral osteosarcoma reveals similarities with appendicular osteosarcoma. PLoS One. 2025; 20(6):e0325181.

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Greengard E, Williams R, Moriarity B, Liu X, Minard CG, Reid JM, Fisher T, Evans E, Pastore DR, Zauderer M, Voss S, Fox E, Weigel BJ. A phase 1/2 study of pepinemab in children, adolescents, or young adults with recurrent or refractory solid tumors: A children's oncology group consortium report (ADVL1614). Pediatr Blood Cancer. 2024 Jun; 71(6):e30938.

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Megquier K, Turner-Maier J, Morrill K, Li X, Johnson J, Karlsson EK, London CA, Gardner HL. The genomic landscape of canine osteosarcoma cell lines reveals conserved structural complexity and pathway alterations. PLoS One. 2022; 17(9):e0274383.

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Gardner HL, Fenger JM, Roberts RD, London CA. Characterizing the metabolic role of STAT3 in canine osteosarcoma. Vet Comp Oncol. 2022 Dec; 20(4):817-824.

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Moena D, Nardocci G, Acevedo E, Lian J, Stein G, Stein J, Montecino M. Ezh2-dependent H3K27me3 modification dynamically regulates vitamin D3-dependent epigenetic control of CYP24A1 gene expression in osteoblastic cells. J Cell Physiol. 2020 06; 235(6):5404-5412.

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Gardner HL, Sivaprakasam K, Briones N, Zismann V, Perdigones N, Drenner K, Facista S, Richholt R, Liang W, Aldrich J, Trent JM, Shields PG, Robinson N, Johnson J, Lana S, Houghton P, Fenger J, Lorch G, Janeway KA, London CA, Hendricks WPD. Canine osteosarcoma genome sequencing identifies recurrent mutations in DMD and the histone methyltransferase gene SETD2. Commun Biol. 2019; 2:266.

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Ma H, Tu LC, Chung YC, Naseri A, Grunwald D, Zhang S, Pederson T. Cell cycle- and genomic distance-dependent dynamics of a discrete chromosomal region. J Cell Biol. 2019 05 06; 218(5):1467-1477.

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Mito JK, Mitra D, Barysauskas CM, Mari?o-Enriquez A, Morgan EA, Fletcher CDM, Raut CP, Baldini EH, Doyle LA. A Comparison of Outcomes and Prognostic Features for Radiation-Associated Angiosarcoma of the Breast and Other Radiation-Associated Sarcomas. Int J Radiat Oncol Biol Phys. 2019 06 01; 104(2):425-435.

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Villanueva F, Araya H, Brice?o P, Varela N, Stevenson A, Jerez S, Tempio F, Chnaiderman J, Perez C, Villarroel M, Concha E, Khani F, Thaler R, Salazar-Onfray F, Stein GS, van Wijnen AJ, Galindo M. The cancer-related transcription factor RUNX2 modulates expression and secretion of the matricellular protein osteopontin in osteosarcoma cells to promote adhesion to endothelial pulmonary cells and lung metastasis. J Cell Physiol. 2019 08; 234(8):13659-13679.

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Jakhar R, Luijten MNH, Wong AXF, Cheng B, Guo K, Neo SP, Au B, Kulkarni M, Lim KJ, Maimaiti J, Chong HC, Lim EH, Tan TBK, Ong KW, Sim Y, Wong JSL, Khoo JBK, Ho JTS, Chua BT, Sinha I, Wang X, Connolly JE, Gunaratne J, Crasta KC. Autophagy Governs Protumorigenic Effects of Mitotic Slippage-induced Senescence. Mol Cancer Res. 2018 11; 16(11):1625-1640.

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