Interleukin-13 Receptor alpha1 Subunit

"Interleukin-13 Receptor alpha1 Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An interleukin receptor subunit with specificity for INTERLEUKIN-13. It dimerizes with the INTERLEUKIN-4 RECEPTOR ALPHA SUBUNIT to form the TYPE II INTERLEUKIN-4 RECEPTOR which has specificity for both INTERLEUKIN-4 and INTERLEUKIN-13. Signaling of this receptor subunit occurs through the interaction of its cytoplasmic domain with JANUS KINASES such as the TYK2 KINASE.

Descriptor ID	D053661
MeSH Number(s)	D12.776.543.750.705.852.420.360.600.500 D12.776.543.750.705.852.420.600.800.500
Concept/Terms	Interleukin-13 Receptor alpha1 Subunit Interleukin-13 Receptor alpha1 Subunit Interleukin 13 Receptor alpha1 Subunit Interleukin-4, 13 Receptor Shared Subunit Interleukin 4, 13 Receptor Shared Subunit Interleukin-13 Receptor alpha1 Chain Interleukin 13 Receptor alpha1 Chain Antigens, CD213a1 CD213a1 Antigens IL-13Ralpha1 CD213a1 Antigen Antigen, CD213a1

Below are MeSH descriptors whose meaning is more general than "Interleukin-13 Receptor alpha1 Subunit".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, Immunologic [D12.776.543.750.705]
Receptors, Cytokine [D12.776.543.750.705.852]
Receptors, Interleukin [D12.776.543.750.705.852.420]
Receptors, Interleukin-4 [D12.776.543.750.705.852.420.360]
Receptors, Interleukin-4, Type II [D12.776.543.750.705.852.420.360.600]
Interleukin-13 Receptor alpha1 Subunit [D12.776.543.750.705.852.420.360.600.500]
Receptors, Interleukin-13 [D12.776.543.750.705.852.420.600]
Receptors, Interleukin-4, Type II [D12.776.543.750.705.852.420.600.800]
Interleukin-13 Receptor alpha1 Subunit [D12.776.543.750.705.852.420.600.800.500]

Below are MeSH descriptors whose meaning is related to "Interleukin-13 Receptor alpha1 Subunit".

Below are MeSH descriptors whose meaning is more specific than "Interleukin-13 Receptor alpha1 Subunit".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Interleukin-13 Receptor alpha1 Subunit" by people in this website by year, and whether "Interleukin-13 Receptor alpha1 Subunit" was a major or minor topic of these publications.

Bar chart showing 4 publications over 3 distinct years, with a maximum of 2 publications in 2004

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
2004	2	2
2006	1	1
2022	1	1

Below are the most recent publications written about "Interleukin-13 Receptor alpha1 Subunit" by people in Profiles.

D'Arcy Q, Gharaee-Kermani M, Zhilin-Roth A, Macoska JA. The IL-4/IL-13 signaling axis promotes prostatic fibrosis. PLoS One. 2022; 17(10):e0275064.

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Sun R, Urban JF, Notari L, Vanuytsel T, Madden KB, Bohl JA, Ramalingam TR, Wynn TA, Zhao A, Shea-Donohue T. Interleukin-13 Receptor a1-Dependent Responses in the Intestine Are Critical to Parasite Clearance. Infect Immun. 2016 Apr; 84(4):1032-1044.

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Ramalingam TR, Pesce JT, Sheikh F, Cheever AW, Mentink-Kane MM, Wilson MS, Stevens S, Valenzuela DM, Murphy AJ, Yancopoulos GD, Urban JF, Donnelly RP, Wynn TA. Unique functions of the type II interleukin 4 receptor identified in mice lacking the interleukin 13 receptor alpha1 chain. Nat Immunol. 2008 Jan; 9(1):25-33.

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Lama VN, Harada H, Badri LN, Flint A, Hogaboam CM, McKenzie A, Martinez FJ, Toews GB, Moore BB, Pinsky DJ. Obligatory role for interleukin-13 in obstructive lesion development in airway allografts. Am J Pathol. 2006 Jul; 169(1):47-60.

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Morimoto M, Morimoto M, Zhao A, Madden KB, Dawson H, Finkelman FD, Mentink-Kane M, Urban JF, Wynn TA, Shea-Donohue T. Functional importance of regional differences in localized gene expression of receptors for IL-13 in murine gut. J Immunol. 2006 Jan 01; 176(1):491-5.

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Zarlenga DS, Dawson H, Kringel H, Solano-Aguilar G, Urban JF. Molecular cloning of the swine IL-4 receptor alpha and IL-13 receptor 1-chains: effects of experimental Toxoplasma gondii, Ascaris suum and Trichuris suis infections on tissue mRNA levels. Vet Immunol Immunopathol. 2004 Oct; 101(3-4):223-34.

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Jakubzick C, Choi ES, Carpenter KJ, Kunkel SL, Evanoff H, Martinez FJ, Flaherty KR, Toews GB, Colby TV, Travis WD, Joshi BH, Puri RK, Hogaboam CM. Human pulmonary fibroblasts exhibit altered interleukin-4 and interleukin-13 receptor subunit expression in idiopathic interstitial pneumonia. Am J Pathol. 2004 Jun; 164(6):1989-2001.

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Jakubzick C, Choi ES, Kunkel SL, Evanoff H, Martinez FJ, Puri RK, Flaherty KR, Toews GB, Colby TV, Kazerooni EA, Gross BH, Travis WD, Hogaboam CM. Augmented pulmonary IL-4 and IL-13 receptor subunit expression in idiopathic interstitial pneumonia. J Clin Pathol. 2004 May; 57(5):477-86.

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Morse B, Sypek JP, Donaldson DD, Haley KJ, Lilly CM. Effects of IL-13 on airway responses in the guinea pig. Am J Physiol Lung Cell Mol Physiol. 2002 Jan; 282(1):L44-9.

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