Cyclin-Dependent Kinase Inhibitor p57
"Cyclin-Dependent Kinase Inhibitor p57" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent inhibitor of CYCLIN-DEPENDENT KINASES in G1 PHASE and S PHASE. In humans, aberrant expression of p57 is associated with various NEOPLASMS as well as with BECKWITH-WIEDEMANN SYNDROME.
| Descriptor ID |
D050761
|
| MeSH Number(s) |
D12.644.360.225.700 D12.776.167.187.700 D12.776.476.225.700 D12.776.624.776.355.700
|
| Concept/Terms |
Cyclin-Dependent Kinase Inhibitor p57- Cyclin-Dependent Kinase Inhibitor p57
- Cyclin Dependent Kinase Inhibitor p57
- p57 KIP2 Protein
- KIP2 Protein, p57
- p57KIP2 Protein
- Cyclin-Dependent Kinase Inhibitor 1C
- Cyclin Dependent Kinase Inhibitor 1C
- Cyclin Kinase Inhibitor Protein 2
- CDKN1C Protein
|
Below are MeSH descriptors whose meaning is more general than "Cyclin-Dependent Kinase Inhibitor p57".
Below are MeSH descriptors whose meaning is more specific than "Cyclin-Dependent Kinase Inhibitor p57".
This graph shows the total number of publications written about "Cyclin-Dependent Kinase Inhibitor p57" by people in this website by year, and whether "Cyclin-Dependent Kinase Inhibitor p57" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cyclin-Dependent Kinase Inhibitor p57" by people in Profiles.
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Socolovsky M. The role of specialized cell cycles during erythroid lineage development: insights from single-cell RNA sequencing. Int J Hematol. 2022 Aug; 116(2):163-173.
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Hwang Y, Futran M, Hidalgo D, Pop R, Iyer DR, Scully R, Rhind N, Socolovsky M. Global increase in replication fork speed during a p57KIP2-regulated erythroid cell fate switch. Sci Adv. 2017 May; 3(5):e1700298.
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Aguilar R, Bustos FJ, Saez M, Rojas A, Allende ML, van Wijnen AJ, van Zundert B, Montecino M. Polycomb PRC2 complex mediates epigenetic silencing of a critical osteogenic master regulator in the hippocampus. Biochim Biophys Acta. 2016 08; 1859(8):1043-55.
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Pop R, Shearstone JR, Shen Q, Liu Y, Hallstrom K, Koulnis M, Gribnau J, Socolovsky M. A key commitment step in erythropoiesis is synchronized with the cell cycle clock through mutual inhibition between PU.1 and S-phase progression. PLoS Biol. 2010 Sep 21; 8(9).
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Mitra P, Ghule PN, van der Deen M, Medina R, Xie RL, Holmes WF, Ye X, Nakayama KI, Harper JW, Stein JL, Stein GS, van Wijnen AJ. CDK inhibitors selectively diminish cell cycle controlled activation of the histone H4 gene promoter by p220NPAT and HiNF-P. J Cell Physiol. 2009 May; 219(2):438-48.
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Rivera RM, Stein P, Weaver JR, Mager J, Schultz RM, Bartolomei MS. Manipulations of mouse embryos prior to implantation result in aberrant expression of imprinted genes on day 9.5 of development. Hum Mol Genet. 2008 Jan 01; 17(1):1-14.
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Mitra P, Xie R, Harper JW, Stein JL, Stein GS, van Wijnen AJ. HiNF-P is a bifunctional regulator of cell cycle controlled histone H4 gene transcription. J Cell Biochem. 2007 May 01; 101(1):181-91.