Drug Resistance, Multiple, Bacterial

"Drug Resistance, Multiple, Bacterial" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The ability of bacteria to resist or to become tolerant to several structurally and functionally distinct drugs simultaneously. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).

Descriptor ID	D024901
MeSH Number(s)	G06.099.225.812 G06.225.347.812 G07.690.773.984.269.347.812 G07.690.773.984.300.500
Concept/Terms	Drug Resistance, Multiple, Bacterial Drug Resistance, Multiple, Bacterial Multiple Antibacterial Drug Resistance

Below are MeSH descriptors whose meaning is more general than "Drug Resistance, Multiple, Bacterial".

Biological Sciences [G]
Microbiological Phenomena [G06]
Bacterial Physiological Phenomena [G06.099]
Drug Resistance, Bacterial [G06.099.225]
Drug Resistance, Multiple, Bacterial [G06.099.225.812]
Drug Resistance, Microbial [G06.225]
Drug Resistance, Bacterial [G06.225.347]
Drug Resistance, Multiple, Bacterial [G06.225.347.812]
Physiological Phenomena [G07]
Pharmacological and Toxicological Phenomena [G07.690]
Pharmacological Phenomena [G07.690.773]
Drug Resistance [G07.690.773.984]
Drug Resistance, Microbial [G07.690.773.984.269]
Drug Resistance, Bacterial [G07.690.773.984.269.347]
Drug Resistance, Multiple, Bacterial [G07.690.773.984.269.347.812]
Drug Resistance, Multiple [G07.690.773.984.300]
Drug Resistance, Multiple, Bacterial [G07.690.773.984.300.500]

Below are MeSH descriptors whose meaning is related to "Drug Resistance, Multiple, Bacterial".

Below are MeSH descriptors whose meaning is more specific than "Drug Resistance, Multiple, Bacterial".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Drug Resistance, Multiple, Bacterial" by people in this website by year, and whether "Drug Resistance, Multiple, Bacterial" was a major or minor topic of these publications.

Bar chart showing 47 publications over 20 distinct years, with a maximum of 5 publications in 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	1	0	1
2004	0	1	1
2006	1	0	1
2008	1	2	3
2009	1	1	2
2011	1	2	3
2012	1	1	2
2013	2	2	4
2014	1	1	2
2015	1	0	1
2016	1	2	3
2017	2	0	2
2018	2	0	2
2019	2	2	4
2020	4	1	5
2021	0	2	2
2022	0	1	1
2023	0	2	2
2024	3	1	4
2025	1	1	2

Below are the most recent publications written about "Drug Resistance, Multiple, Bacterial" by people in Profiles.

Hikal AF, Zhao S, Foley S, Khan AA. The newly identified grdA gene confers high-level plazomicin resistance in Salmonella enterica serovars. Antimicrob Agents Chemother. 2025 May 07; 69(5):e0160624.

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Sharma S, Raju S, Verma SK, Verma R, Thakur PK, Sharath Kumar KS. Pyrazoles: A Master Key to Tackle Multidrug-Resistant Acinetobacter baumannii and Its Structure Activity Relationship Studies. Chem Biol Drug Des. 2025 Mar; 105(3):e70092.

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Nabawy A, Chattopadhyay AN, Makabenta JMV, Hassan MA, Yang J, Park J, Jiang M, Jeon T, Im J, Rotello VM. Cationic conjugated polymers with tunable hydrophobicity for efficient treatment of multidrug-resistant wound biofilm infections. Biomaterials. 2025 May; 316:123015.

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Raviranga NGH, Ayinla M, Perera HA, Qi Y, Yan M, Ramstr?m O. Antimicrobial Potency of Nor-Pyochelin Analogues and Their Cation Complexes against Multidrug-Resistant Pathogens. ACS Infect Dis. 2024 Nov 08; 10(11):3842-3852.

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Sung K, Nawaz M, Park M, Chon J, Khan SA, Alotaibi K, Khan AA. Comprehensive Genomic Analysis of Uropathogenic E. coli: Virulence Factors, Antimicrobial Resistance, and Mobile Genetic Elements. Pathogens. 2024 Sep 13; 13(9).

View in: PubMed
Blasco B, Jang S, Terauchi H, Kobayashi N, Suzuki S, Akao Y, Ochida A, Morishita N, Takagi T, Nagamiya H, Suzuki Y, Watanabe T, Lee H, Lee S, Shum D, Cho A, Koh D, Park S, Lee H, Kim K, Ropponen HK, Augusto da Costa RM, Dunn S, Ghosh S, Sj? P, Piddock LJV. High-throughput screening of small-molecules libraries identified antibacterials against clinically relevant multidrug-resistant A.?baumannii and K.?pneumoniae. EBioMedicine. 2024 Apr; 102:105073.

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Makabenta JMV, Nabawy A, Chattopadhyay AN, Jeon T, Park J, Lo PC, Nosovitski S, Huang R, Li CH, Jiang M, Rotello VM. Antimicrobial polymer-loaded hydrogels for the topical treatment of multidrug-resistant wound biofilm infections. J Control Release. 2023 10; 362:513-523.

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Park J, Nabawy A, Doungchawee J, Mahida N, Foster K, Jantarat T, Jiang M, Chattopadhyay AN, Hassan MA, Agrohia DK, Makabenta JM, Vachet RW, Rotello VM. Synergistic Treatment of Multidrug-Resistant Bacterial Biofilms Using Silver Nanoclusters Incorporated into Biodegradable Nanoemulsions. ACS Appl Mater Interfaces. 2023 Aug 09; 15(31):37205-37213.

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Nabawy A, Makabenta JM, Schmidt-Malan S, Park J, Li CH, Huang R, Fedeli S, Chattopadhyay AN, Patel R, Rotello VM. Dual antimicrobial-loaded biodegradable nanoemulsions for synergistic treatment of wound biofilms. J Control Release. 2022 07; 347:379-388.

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Li X, Le W, Lou X, Wang B, Genco CA, Rice PA, Su X. In Vitro Efficacy of Gentamicin Alone and in Combination with Ceftriaxone, Ertapenem, and Azithromycin against Multidrug-Resistant Neisseria gonorrhoeae. Microbiol Spectr. 2021 10 31; 9(2):e0018121.

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