Drug Resistance

"Drug Resistance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Diminished or failed response of an organism, disease or tissue to the intended effectiveness of a chemical or drug. It should be differentiated from DRUG TOLERANCE which is the progressive diminution of the susceptibility of a human or animal to the effects of a drug, as a result of continued administration.

Descriptor ID	D004351
MeSH Number(s)	G07.690.773.984
Concept/Terms	Drug Resistance Drug Resistance Resistance, Drug

Below are MeSH descriptors whose meaning is more general than "Drug Resistance".

Biological Sciences [G]
Physiological Phenomena [G07]
Pharmacological and Toxicological Phenomena [G07.690]
Pharmacological Phenomena [G07.690.773]
Drug Resistance [G07.690.773.984]

Below are MeSH descriptors whose meaning is related to "Drug Resistance".

Below are MeSH descriptors whose meaning is more specific than "Drug Resistance".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Drug Resistance" by people in this website by year, and whether "Drug Resistance" was a major or minor topic of these publications.

Bar chart showing 77 publications over 24 distinct years, with a maximum of 9 publications in 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
1996	0	3	3
2001	0	1	1
2003	0	2	2
2004	0	2	2
2005	6	1	7
2006	2	4	6
2007	0	5	5
2008	1	2	3
2009	0	3	3
2010	1	1	2
2011	4	5	9
2012	0	2	2
2013	0	2	2
2014	1	2	3
2015	1	1	2
2017	1	1	2
2018	2	1	3
2019	1	0	1
2020	2	2	4
2021	2	1	3
2022	0	5	5
2023	0	4	4
2024	1	1	2

Below are the most recent publications written about "Drug Resistance" by people in Profiles.

Kreutzfeld O, Orena S, Okitwi M, Tumwebaze PK, Byaruhanga O, Katairo T, Conrad MD, Legac J, Garg S, Crudale R, Aydemir O, Giesbrecht D, Nsobya SL, Blasco B, Duffey M, Rouillier M, Bailey JA, Cooper RA, Rosenthal PJ. Ex vivo susceptibilities to ganaplacide and diversity in potential resistance mediators in Ugandan Plasmodium falciparum isolates. Antimicrob Agents Chemother. 2024 09 04; 68(9):e0046624.

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Flynn JM, Zvornicanin SN, Tsepal T, Shaqra AM, Kurt Yilmaz N, Jia W, Moquin S, Dovala D, Schiffer CA, Bolon DNA. Contributions of Hyperactive Mutations in Mpro from SARS-CoV-2 to Drug Resistance. ACS Infect Dis. 2024 04 12; 10(4):1174-1184.

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Aroian RV, Loukas A, Martin RJ. Anthelmintics V: Drugs, resistance, and vaccines. Int J Parasitol. 2023 07; 53(8):391-392.

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Kreutzfeld O, Tumwebaze PK, Okitwi M, Orena S, Byaruhanga O, Katairo T, Conrad MD, Rasmussen SA, Legac J, Aydemir O, Giesbrecht D, Forte B, Campbell P, Smith A, Kano H, Nsobya SL, Blasco B, Duffey M, Bailey JA, Cooper RA, Rosenthal PJ. Susceptibility of Ugandan Plasmodium falciparum Isolates to the Antimalarial Drug Pipeline. Microbiol Spectr. 2023 06 15; 11(3):e0523622.

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Shaver AO, Wit J, Dilks CM, Crombie TA, Li H, Aroian RV, Andersen EC. Variation in anthelmintic responses are driven by genetic differences among diverse C. elegans wild strains. PLoS Pathog. 2023 04; 19(4):e1011285.

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Flynn J, Samant N, Schneider-Nachum G, Tenzin T, Bolon DNA. Mutational fitness landscape and drug resistance. Curr Opin Struct Biol. 2023 02; 78:102525.

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Garg S, Kreutzfeld O, Chelebieva S, Tumwebaze PK, Byaruhanga O, Okitwi M, Orena S, Katairo T, Nsobya SL, Conrad MD, Aydemir O, Legac J, Gould AE, Bayles BR, Bailey JA, Duffey M, Lin G, Kirkman LA, Cooper RA, Rosenthal PJ. Susceptibilities of Ugandan Plasmodium falciparum Isolates to Proteasome Inhibitors. Antimicrob Agents Chemother. 2022 10 18; 66(10):e0081722.

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Shaqra AM, Zvornicanin SN, Huang QYJ, Lockbaum GJ, Knapp M, Tandeske L, Bakan DT, Flynn J, Bolon DNA, Moquin S, Dovala D, Kurt Yilmaz N, Schiffer CA. Defining the substrate envelope of SARS-CoV-2 main protease to predict and avoid drug resistance. Nat Commun. 2022 06 21; 13(1):3556.

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Pritchard JR, Lee MJ, Peyton SR. Materials-driven approaches to understand extrinsic drug resistance in cancer. Soft Matter. 2022 May 11; 18(18):3465-3472.

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Schiffer CA, Hazuda DJ. Call for Papers: Drug Resistance in Infectious Diseases and Beyond. ACS Infect Dis. 2022 04 08; 8(4):665-666.

View in: PubMed

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