Drug Interactions

"Drug Interactions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The action of a drug that may affect the activity, metabolism, or toxicity of another drug.

Descriptor ID	D004347
MeSH Number(s)	G07.690.773.968
Concept/Terms	Drug Interactions Drug Interactions Drug Interaction Interaction, Drug Interactions, Drug

Below are MeSH descriptors whose meaning is more general than "Drug Interactions".

Biological Sciences [G]
Physiological Phenomena [G07]
Pharmacological and Toxicological Phenomena [G07.690]
Pharmacological Phenomena [G07.690.773]
Drug Interactions [G07.690.773.968]

Below are MeSH descriptors whose meaning is related to "Drug Interactions".

Below are MeSH descriptors whose meaning is more specific than "Drug Interactions".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Drug Interactions" by people in this website by year, and whether "Drug Interactions" was a major or minor topic of these publications.

Bar chart showing 101 publications over 28 distinct years, with a maximum of 11 publications in 2007

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	2	2
1997	0	2	2
1998	0	1	1
1999	0	2	2
2000	0	2	2
2001	0	1	1
2002	0	4	4
2003	0	1	1
2004	0	4	4
2005	0	9	9
2006	0	7	7
2007	0	11	11
2008	1	3	4
2009	0	5	5
2010	0	7	7
2011	0	6	6
2012	0	5	5
2013	0	4	4
2014	0	3	3
2015	0	1	1
2016	0	4	4
2017	1	3	4
2018	0	2	2
2019	0	3	3
2020	0	2	2
2021	0	1	1
2022	1	1	2
2025	0	2	2

Below are the most recent publications written about "Drug Interactions" by people in Profiles.

O'Mahony ET, Arian CM, Aryeh KS, Wang K, Thummel KE, Kelly EJ. Human intestinal enteroids: Nonclinical applications for predicting oral drug disposition, toxicity, and efficacy. Pharmacol Ther. 2025 Sep; 273:108879.

View in: PubMed
Arian CM, O'Mahony ET, Manwill PK, Graf TN, Oberlies NH, Cech NB, Clarke JD, Smith JG, Paine MF, Kelly EJ, Thummel KE. A gut response: Application of human enteroid monolayers to probe the mechanism of the goldenseal-mediated inhibition of metformin intestinal absorption. J Pharmacol Exp Ther. 2025 Jun; 392(6):103597.

View in: PubMed
Abraham S, Nohria A, Neilan TG, Asnani A, Saji AM, Shah J, Lech T, Grossman J, Abraham GM, McQuillen DP, Martin DT, Sax PE, Dani SS, Ganatra S. Cardiovascular Drug Interactions With?Nirmatrelvir/Ritonavir in Patients?With COVID-19: JACC?Review Topic of the Week. J Am Coll Cardiol. 2022 11 15; 80(20):1912-1924.

View in: PubMed
Schoretsanitis G, Deligiannidis KM, Paulzen M, Spina E, de Leon J. Drug-drug interactions between psychotropic medications and oral contraceptives. Expert Opin Drug Metab Toxicol. 2022 Jun; 18(6):395-411.

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Koh EI, Oluoch PO, Ruecker N, Proulx MK, Soni V, Murphy KC, Papavinasasundaram K, Reames CJ, Trujillo C, Zaveri A, Zimmerman MD, Aslebagh R, Baker RE, Shaffer SA, Guinn KM, Fitzgerald M, Dartois V, Ehrt S, Hung DT, Ioerger TR, Rubin EJ, Rhee KY, Schnappinger D, Sassetti CM. Chemical-genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy. Proc Natl Acad Sci U S A. 2022 04 12; 119(15):e2201632119.

View in: PubMed
Rothschild AJ. The Pitfalls of Psychotropic Polypharmacy. J Clin Psychopharmacol. 2021 May-Jun 01; 41(3):227-232.

View in: PubMed
Sun W, Lirio RA, Schneider J, Aubrecht J, Kadali H, Baratta M, Gulati P, Suri A, Lin T, Vasudevan R, Rosario M. Assessment of Vedolizumab Disease-Drug-Drug Interaction Potential in Patients With Inflammatory Bowel Diseases. Clin Pharmacol Drug Dev. 2021 07; 10(7):734-747.

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Neumann NR, Chai PR, Wood DM, Greller HA, Mycyk MB. Medical Toxicology and COVID-19: Our Role in a Pandemic. J Med Toxicol. 2020 07; 16(3):245-247.

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Sanghai S, Wong C, Wang Z, Clive P, Tran W, Waring M, Goldberg R, Hayward R, Saczynski JS, McManus DD. Rates of Potentially Inappropriate Dosing of Direct-Acting Oral Anticoagulants and Associations With Geriatric Conditions Among Older Patients With Atrial Fibrillation: The SAGE-AF Study. J Am Heart Assoc. 2020 03 17; 9(6):e014108.

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Maslov MY, Foianini S, Mayer D, Orlov MV, Lovich MA. Interaction Between Sacubitril and Valsartan in Preventing Heart Failure Induced by Aortic Valve Insufficiency in Rats. J Card Fail. 2019 Nov; 25(11):921-931.

View in: PubMed

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