"Drug Inverse Agonism" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Phenomena and pharmaceutics of compounds that bind to the same receptor binding-site as an agonist (DRUG AGONISM) for that receptor but exerts the opposite pharmacological effect.
| Descriptor ID |
D054314
|
| MeSH Number(s) |
G07.690.773.968.393
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Drug Inverse Agonism".
Below are MeSH descriptors whose meaning is more specific than "Drug Inverse Agonism".
This graph shows the total number of publications written about "Drug Inverse Agonism" by people in this website by year, and whether "Drug Inverse Agonism" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
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Below are the most recent publications written about "Drug Inverse Agonism" by people in Profiles.
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Saab BJ, Maclean AJ, Kanisek M, Zurek AA, Martin LJ, Roder JC, Orser BA. Short-term memory impairment after isoflurane in mice is prevented by the a5 ?-aminobutyric acid type A receptor inverse agonist L-655,708. Anesthesiology. 2010 Nov; 113(5):1061-71.
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Przyklenk K, Frelinger AL, Linden MD, Whittaker P, Li Y, Barnard MR, Adams J, Morgan M, Al-Shamma H, Michelson AD. Targeted inhibition of the serotonin 5HT2A receptor improves coronary patency in an in vivo model of recurrent thrombosis. J Thromb Haemost. 2010 Feb; 8(2):331-40.