Imidazoles

"Imidazoles" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Compounds containing 1,3-diazole, a five membered aromatic ring containing two nitrogen atoms separated by one of the carbons. Chemically reduced ones include IMIDAZOLINES and IMIDAZOLIDINES. Distinguish from 1,2-diazole (PYRAZOLES).

Descriptor ID	D007093
MeSH Number(s)	D03.383.129.308
Concept/Terms	Imidazoles Imidazoles

Below are MeSH descriptors whose meaning is more general than "Imidazoles".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, 1-Ring [D03.383]
Azoles [D03.383.129]
Imidazoles [D03.383.129.308]

Below are MeSH descriptors whose meaning is related to "Imidazoles".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Imidazoles" by people in this website by year, and whether "Imidazoles" was a major or minor topic of these publications.

Bar chart showing 63 publications over 25 distinct years, with a maximum of 6 publications in 2013 and 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	1	2
1996	1	0	1
1998	0	2	2
2000	1	1	2
2002	1	0	1
2003	0	1	1
2004	0	2	2
2005	0	3	3
2006	0	3	3
2007	0	1	1
2008	1	2	3
2010	1	3	4
2011	1	1	2
2012	3	2	5
2013	2	4	6
2014	1	5	6
2015	1	3	4
2017	2	0	2
2018	0	1	1
2019	0	2	2
2020	2	3	5
2021	1	0	1
2022	0	1	1
2024	1	1	2
2025	0	1	1

Below are the most recent publications written about "Imidazoles" by people in Profiles.

Mita MM, Mita AC, Carver BJ, Shanahan JM, Mayes BA, Dufour PJ, Browning D, Anderson-Villaluz A, Petersen JS, Turnquist DJ, Cornelius P. A Phase 1 Safety Study of Evexomostat (SDX-7320) in Patients with Late-Stage Cancer: An Antiangiogenic, Insulin-Sensitizing Drug Conjugate Targeting METAP2. Cancer Res Commun. 2025 Jun 01; 5(6):1008-1017.

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Wang M, Prachyathipsakul T, Silva CA, Xiong C, Goel S, Goel HL, Karner ER, Mukhopadhyay D, Gupta P, Majee A, Thayumanavan S, Mercurio AM. Therapeutic induction of ferroptosis in tumors using PD-L1 targeting antibody nanogel conjugates. Cell Chem Biol. 2024 12 19; 31(12):2039-2051.e6.

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Alizadeh Sani M, Khezerlou A, McClements DJ. Zeolitic imidazolate frameworks (ZIFs): Advanced nanostructured materials to enhance the functional performance of food packaging materials. Adv Colloid Interface Sci. 2024 May; 327:103153.

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Ferrari LL, Ogbeide-Latario OE, Gompf HS, Anaclet C. Validation of DREADD agonists and administration route in a murine model of sleep enhancement. J Neurosci Methods. 2022 Oct 01; 380:109679.

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Tambiah JRS, Simsek I, Swearingen CJ, Kennedy S, Cole BJ, McAlindon TE, Yazici Y. Comparing Patient-Reported Outcomes From Sham and Saline-Based Placebo Injections for Knee Osteoarthritis: Data From a Randomized Clinical Trial of Lorecivivint. Am J Sports Med. 2022 Mar; 50(3):630-636.

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Tahtouh T, Durieu E, Villiers B, Bruy?re C, Nguyen TL, Fant X, Ahn KH, Khurana L, Deau E, Lindberg MF, S?v?re E, Miege F, Roche D, Limanton E, L'Helgoual'ch JM, Burgy G, Guiheneuf S, Herault Y, Kendall DA, Carreaux F, Bazureau JP, Meijer L. Structure-Activity Relationship in the Leucettine Family of Kinase Inhibitors. J Med Chem. 2022 01 27; 65(2):1396-1417.

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Yazici Y, McAlindon TE, Gibofsky A, Lane NE, Lattermann C, Skrepnik N, Swearingen CJ, Simsek I, Ghandehari H, DiFrancesco A, Gibbs J, Tambiah JRS, Hochberg MC. A Phase 2b randomized trial of lorecivivint, a novel intra-articular CLK2/DYRK1A inhibitor and Wnt pathway modulator for knee osteoarthritis. Osteoarthritis Cartilage. 2021 05; 29(5):654-666.

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Bok S, Shin DY, Yallowitz AR, Eiseman M, Cung M, Xu R, Li N, Sun J, Williams AL, Scott JE, Su B, Shim JH, Greenblatt MB. MEKK2 mediates aberrant ERK activation in neurofibromatosis type I. Nat Commun. 2020 11 11; 11(1):5704.

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Lowe PP, Morel C, Ambade A, Iracheta-Vellve A, Kwiatkowski E, Satishchandran A, Furi I, Cho Y, Gyongyosi B, Catalano D, Lefebvre E, Fischer L, Seyedkazemi S, Schafer DP, Szabo G. Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations. J Neuroinflammation. 2020 Oct 09; 17(1):296.

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Singh O, Lee PY, Matysiak S, Bermudez H. Dual mechanism of ionic liquid-induced protein unfolding. Phys Chem Chem Phys. 2020 Sep 16; 22(35):19779-19786.

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