"Dexmedetomidine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A imidazole derivative that is an agonist of ADRENERGIC ALPHA-2 RECEPTORS. It is closely-related to MEDETOMIDINE, which is the racemic form of this compound.
| Descriptor ID |
D020927
|
| MeSH Number(s) |
D03.383.129.308.245
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Dexmedetomidine".
Below are MeSH descriptors whose meaning is more specific than "Dexmedetomidine".
This graph shows the total number of publications written about "Dexmedetomidine" by people in this website by year, and whether "Dexmedetomidine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2014 | 2 | 1 | 3 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Dexmedetomidine" by people in Profiles.
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Mahboobi SK. Dexmedetomidine and Renal Protection after Cardiac Surgery. J Clin Anesth. 2017 08; 40:121-122.
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Wu Y, Zhang XB, Qian YN, Xiao H. [The protective effects of dexmedetomidine on perioperative myocardial injury in patients with hypertensive myocardial hypertrophy]. Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2016 May 08; 32(5):459-462.
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Mahmoud M, Mason KP. A forecast of relevant pediatric sedation trends. Curr Opin Anaesthesiol. 2016 Mar; 29 Suppl 1:S56-67.
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Darnobid JA. The pharmacology of total intravenous anesthesia. Int Anesthesiol Clin. 2015; 53(2):13-27.
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McCarren HS, Chalifoux MR, Han B, Moore JT, Meng QC, Baron-Hionis N, Sedigh-Sarvestani M, Contreras D, Beck SG, Kelz MB. a2-Adrenergic stimulation of the ventrolateral preoptic nucleus destabilizes the anesthetic state. J Neurosci. 2014 Dec 03; 34(49):16385-96.
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Zhang X, Wang J, Qian W, Zhao J, Sun L, Qian Y, Xiao H. Dexmedetomidine inhibits inducible nitric oxide synthase in lipopolysaccharide-stimulated microglia by suppression of extracellular signal-regulated kinase. Neurol Res. 2015 Mar; 37(3):238-45.
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Devlin JW, Al-Qadheeb NS, Chi A, Roberts RJ, Qawi I, Garpestad E, Hill NS. Efficacy and safety of early dexmedetomidine during noninvasive ventilation for patients with acute respiratory failure: a randomized, double-blind, placebo-controlled pilot study. Chest. 2014 Jun; 145(6):1204-1212.
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Goddeau RP, Silverman SB, Sims JR. Dexmedetomidine for the treatment of paroxysmal autonomic instability with dystonia. Neurocrit Care. 2007; 7(3):217-20.
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Bekker AY, Basile J, Gold M, Riles T, Adelman M, Cuff G, Mathew JP, Goldberg JD. Dexmedetomidine for awake carotid endarterectomy: efficacy, hemodynamic profile, and side effects. J Neurosurg Anesthesiol. 2004 Apr; 16(2):126-35.