"Drug Antagonism" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Phenomena and pharmaceutics of compounds that inhibit the function of agonists (DRUG AGONISM) and inverse agonists (DRUG INVERSE AGONISM) for a specific receptor. On their own, antagonists produce no effect by themselves to a receptor, and are said to have neither intrinsic activity nor efficacy.
| Descriptor ID |
D004336
|
| MeSH Number(s) |
G07.690.773.968.310
|
| Concept/Terms |
Drug Antagonism- Drug Antagonism
- Antagonism, Drug
- Antagonisms, Drug
- Drug Antagonisms
|
Below are MeSH descriptors whose meaning is more general than "Drug Antagonism".
Below are MeSH descriptors whose meaning is more specific than "Drug Antagonism".
This graph shows the total number of publications written about "Drug Antagonism" by people in this website by year, and whether "Drug Antagonism" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Drug Antagonism" by people in Profiles.
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Richards R, Schwartz HR, Honeywell ME, Stewart MS, Cruz-Gordillo P, Joyce AJ, Landry BD, Lee MJ. Drug antagonism and single-agent dominance result from differences in death kinetics. Nat Chem Biol. 2020 07; 16(7):791-800.
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Patel RC, Stalter RM, Thomas KK, Tamraz B, Blue SW, Erikson DW, Kim CJ, Kelly EJ, Nanda K, Kourtis AP, Lingappa JR, Mugo N, Baeten JM, Scarsi KK. A pharmacokinetic and pharmacogenetic evaluation of contraceptive implants and antiretroviral therapy among women in Kenya and Uganda. AIDS. 2019 11 01; 33(13):1995-2004.
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Le NDB, Wang X, Geng Y, Tang R, Tonga GY, Jiang Z, Rotello VM. Rapid and ultrasensitive detection of endocrine disrupting chemicals using a nanosensor-enabled cell-based platform. Chem Commun (Camb). 2017 Aug 11; 53(62):8794-8797.
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Panya A, Kittipongpittaya K, Laguerre M, Bayrasy C, Lecomte J, Villeneuve P, McClements DJ, Decker EA. Interactions between a-tocopherol and rosmarinic acid and its alkyl esters in emulsions: synergistic, additive, or antagonistic effect? J Agric Food Chem. 2012 Oct 17; 60(41):10320-30.
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Tamez PA, Lantvit D, Lim E, Pezzuto JM. Chemosensitizing action of cepharanthine against drug-resistant human malaria, Plasmodium falciparum. J Ethnopharmacol. 2005 Apr 08; 98(1-2):137-42.
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Izawa A, Sayegh MH, Chandraker A. The antagonism of calcineurin inhibitors and costimulatory blockers: fact or fiction? Transplant Proc. 2004 Mar; 36(2 Suppl):570S-573S.
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Krieg AM, Yi AK. Rescue of B cells from apoptosis by immune stimulatory CpG DNA. Springer Semin Immunopathol. 2000; 22(1-2):55-61.
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Blaustein JD, Wade GN. Sequential inhibition of sexual behavior by progesterone in female rats: comparison with a synthetic antiestrogen. J Comp Physiol Psychol. 1977 Aug; 91(4):752-60.
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Blaustein JD, Wade GN. Concurrent inhibition of sexual behavior, but not brain [3H]estradiol uptake, by progesterone in female rats. J Comp Physiol Psychol. 1977 Aug; 91(4):742-51.