Malaria, Falciparum

"Malaria, Falciparum" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.

Descriptor ID	D016778
MeSH Number(s)	C03.752.530.650
Concept/Terms	Malaria, Falciparum Malaria, Falciparum Plasmodium falciparum Malaria Malaria, Plasmodium falciparum

Below are MeSH descriptors whose meaning is more general than "Malaria, Falciparum".

Diseases [C]
Parasitic Diseases [C03]
Protozoan Infections [C03.752]
Malaria [C03.752.530]
Malaria, Falciparum [C03.752.530.650]

Below are MeSH descriptors whose meaning is related to "Malaria, Falciparum".

Below are MeSH descriptors whose meaning is more specific than "Malaria, Falciparum".

Malaria, Falciparum
Blackwater Fever

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Malaria, Falciparum" by people in this website by year, and whether "Malaria, Falciparum" was a major or minor topic of these publications.

Bar chart showing 95 publications over 26 distinct years, with a maximum of 9 publications in 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	0	1
1998	1	0	1
1999	1	0	1
2003	2	0	2
2004	4	0	4
2005	5	0	5
2006	1	0	1
2007	3	0	3
2008	4	1	5
2009	4	0	4
2010	1	0	1
2011	3	2	5
2012	5	0	5
2013	3	0	3
2014	4	0	4
2015	4	1	5
2016	3	1	4
2017	2	2	4
2018	3	0	3
2019	2	0	2
2020	8	1	9
2021	5	1	6
2022	3	1	4
2023	8	0	8
2024	1	2	3
2025	2	0	2

Below are the most recent publications written about "Malaria, Falciparum" by people in Profiles.

Forconi CS, Nixon C, Wu HW, Odwar B, Pond-Tor S, Ong'echa JM, Kurtis JD, Moormann AM. T-follicular helper cell profiles differ by malaria antigen and for children compared to adults. Elife. 2025 May 22; 13.

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Sobota RS, Stucke EM, Coulibaly D, Lawton JG, Cummings BE, Sebastian S, Dara A, Munro JB, Ouattara A, Kone AK, Kane B, Traor? K, Guindo B, Tangara BM, Niangaly A, Ventimiglia NT, Daou M, Diarra I, Tolo Y, Sissoko M, Maiga F, Diawara A, Traore A, Thera A, Laurens MB, Lyke KE, Kouriba B, Doumbo OK, Plowe CV, Goodlett DR, Silva JC, Thera MA, Travassos MA. A shared inflammatory signature across severe malaria syndromes manifested by transcriptomic, proteomic and metabolomic analyses. Nat Commun. 2025 May 18; 16(1):4620.

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Bonnell VA, Zhang Y, Brown AS, Horton J, Josling GA, Chiu TP, Rohs R, Mahony S, Gord?n R, Llin?s M. DNA sequence and chromatin differentiate sequence-specific transcription factor binding in the human malaria parasite Plasmodium falciparum. Nucleic Acids Res. 2024 Sep 23; 52(17):10161-10179.

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Kreutzfeld O, Orena S, Okitwi M, Tumwebaze PK, Byaruhanga O, Katairo T, Conrad MD, Legac J, Garg S, Crudale R, Aydemir O, Giesbrecht D, Nsobya SL, Blasco B, Duffey M, Rouillier M, Bailey JA, Cooper RA, Rosenthal PJ. Ex vivo susceptibilities to ganaplacide and diversity in potential resistance mediators in Ugandan Plasmodium falciparum isolates. Antimicrob Agents Chemother. 2024 09 04; 68(9):e0046624.

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Connelly SV, Brazeau NF, Msellem M, Ngasala BE, Aydemir O, Goel V, Niar? K, Giesbrecht DJ, Popkin-Hall ZR, Hennelly C, Park Z, Moormann AM, Ong'echa JM, Verity R, Mohammed S, Shija SJ, Mhamilawa LE, Morris U, M?rtensson A, Lin JT, Bj?rkman A, Juliano JJ, Bailey JA. Strong isolation by distance and evidence of population microstructure reflect ongoing Plasmodium falciparum transmission in Zanzibar. Elife. 2024 Jun 27; 12.

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Solebo O, Ling L, Nwankwo I, Zhou J, Fu TM, Ke H. Plasmodium falciparum utilizes pyrophosphate to fuel an essential proton pump in the ring stage and the transition to trophozoite stage. PLoS Pathog. 2023 Dec; 19(12):e1011818.

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Alves SAS, Teixeira DE, Peruchetti DB, Silva LS, Brand?o LFP, Caruso-Neves C, Pinheiro AAS. Bradykinin produced during Plasmodium falciparum erythrocytic cycle drives monocyte adhesion to human brain microvascular endothelial cells. Brain Res. 2024 01 01; 1822:148669.

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Muriuki BM, Forconi CS, Kirwa EK, Maina TK, Ariera BO, Bailey JA, Ghansah A, Moormann AM, Ong'echa JM. Evaluation of KIR3DL1/KIR3DS1 allelic polymorphisms in Kenyan children with endemic Burkitt lymphoma. PLoS One. 2023; 18(8):e0275046.

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Fola AA, Moser KA, Aydemir O, Hennelly C, Kobayashi T, Shields T, Hamapumbu H, Musonda M, Katowa B, Matoba J, Stevenson JC, Norris DE, Thuma PE, Wesolowski A, Moss WJ, Bailey JA, Juliano JJ. Temporal and spatial analysis of Plasmodium falciparum genomics reveals patterns of parasite connectivity in a low-transmission district in Southern Province, Zambia. Malar J. 2023 Jul 07; 22(1):208.

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Paschalidis A, Watson OJ, Aydemir O, Verity R, Bailey JA. coiaf: Directly estimating complexity of infection with allele frequencies. PLoS Comput Biol. 2023 Jun; 19(6):e1010247.

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