Malaria

"Malaria" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.

Descriptor ID	D008288
MeSH Number(s)	C03.752.530
Concept/Terms	Malaria Malaria Remittent Fever Fever, Remittent Paludism Plasmodium Infections Infections, Plasmodium Infection, Plasmodium Plasmodium Infection Marsh Fever Fever, Marsh

Below are MeSH descriptors whose meaning is more general than "Malaria".

Diseases [C]
Parasitic Diseases [C03]
Protozoan Infections [C03.752]
Malaria [C03.752.530]

Below are MeSH descriptors whose meaning is related to "Malaria".

Below are MeSH descriptors whose meaning is more specific than "Malaria".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Malaria" by people in this website by year, and whether "Malaria" was a major or minor topic of these publications.

Bar chart showing 72 publications over 26 distinct years, with a maximum of 5 publications in 2013 and 2014 and 2018 and 2020 and 2023

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
1999	0	1	1
2001	2	0	2
2002	1	0	1
2003	2	0	2
2004	2	0	2
2005	1	0	1
2007	4	0	4
2008	1	0	1
2009	4	0	4
2010	2	0	2
2011	2	1	3
2012	2	2	4
2013	3	2	5
2014	5	0	5
2015	3	1	4
2016	1	0	1
2017	1	0	1
2018	4	1	5
2019	1	1	2
2020	4	1	5
2021	3	0	3
2022	4	0	4
2023	5	0	5
2024	3	0	3
2025	1	0	1

Below are the most recent publications written about "Malaria" by people in Profiles.

Hirako IC, Ramalho T, Gazzinelli RT. Immune regulation of host energy metabolism and periodicity of malaria parasites. Philos Trans R Soc Lond B Biol Sci. 2025 Jan 23; 380(1918):20230511.

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Carey-Ewend K, Popkin-Hall ZR, Simkin A, Muller M, Hennelly C, He W, Moser KA, Gaither C, Niar? K, Aghakanian F, Feleke S, Brhane BG, Phanzu F, Kashamuka MM, Aydemir O, Sutherland CJ, Ishengoma DS, Ali IM, Ngasala B, Kalonji A, Tshefu A, Parr JB, Bailey JA, Juliano JJ, Lin JT. Population genomics of Plasmodium ovale species in sub-Saharan Africa. Nat Commun. 2024 Nov 27; 15(1):10297.

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Ramalho T, Assis PA, Ojelabi O, Tan L, Carvalho B, Gardinassi L, Campos O, Lorenzi PL, Fitzgerald KA, Haynes C, Golenbock DT, Gazzinelli RT. Itaconate impairs immune control of Plasmodium by enhancing mtDNA-mediated PD-L1 expression in monocyte-derived dendritic cells. Cell Metab. 2024 03 05; 36(3):484-497.e6.

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Levine ZC, Sene A, Mkandawire W, Deme AB, Ndiaye T, Sy M, Gaye A, Diedhiou Y, Mbaye AM, Ndiaye IM, Gomis J, Ndiop M, Sene D, Faye Paye M, MacInnis BL, Schaffner SF, Park DJ, Badiane AS, Colubri A, Ndiaye M, Sy N, Sabeti PC, Ndiaye D, Siddle KJ. Investigating the etiologies of non-malarial febrile illness in Senegal using metagenomic sequencing. Nat Commun. 2024 Jan 25; 15(1):747.

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Diniz SQ, Figueiredo MM, Costa PAC, Martins-Filho OA, Teixeira-Carvalho A, Pereira DB, Shugiro Tada M, Crocco Afonso LC, Kohlhoff M, Zani CL, Gazzinelli RT, Oliveira F, Antonelli LR. Adenosine pathway regulates inflammation during Plasmodium vivax infection. Front Immunol. 2023; 14:1193256.

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Fola AA, Moser KA, Aydemir O, Hennelly C, Kobayashi T, Shields T, Hamapumbu H, Musonda M, Katowa B, Matoba J, Stevenson JC, Norris DE, Thuma PE, Wesolowski A, Moss WJ, Bailey JA, Juliano JJ. Temporal and spatial analysis of Plasmodium falciparum genomics reveals patterns of parasite connectivity in a low-transmission district in Southern Province, Zambia. Malar J. 2023 Jul 07; 22(1):208.

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Andrade AO, Santos NAC, Bastos AS, Pontual JDC, Ara?jo JE, Silva AMV, Martinez LN, Lima AA, Aguiar ACC, G Teles CB, Medeiros JF, Pereira DB, Vinetz JM, Gazzinelli RT, Ara?jo MS. Transmission-blocking activity of antimalarials for Plasmodium vivax malaria in Anopheles darlingi. PLoS Negl Trop Dis. 2023 Jun; 17(6):e0011425.

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Paschalidis A, Watson OJ, Aydemir O, Verity R, Bailey JA. coiaf: Directly estimating complexity of infection with allele frequencies. PLoS Comput Biol. 2023 Jun; 19(6):e1010247.

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Kreutzfeld O, Tumwebaze PK, Okitwi M, Orena S, Byaruhanga O, Katairo T, Conrad MD, Rasmussen SA, Legac J, Aydemir O, Giesbrecht D, Forte B, Campbell P, Smith A, Kano H, Nsobya SL, Blasco B, Duffey M, Bailey JA, Cooper RA, Rosenthal PJ. Susceptibility of Ugandan Plasmodium falciparum Isolates to the Antimalarial Drug Pipeline. Microbiol Spectr. 2023 06 15; 11(3):e0523622.

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Hirako IC, Antunes MM, Rezende RM, Hojo-Souza NS, Figueiredo MM, Dias T, Nakaya H, Menezes GB, Gazzinelli RT. Uptake of Plasmodium chabaudi hemozoin drives Kupffer cell death and fuels superinfections. Sci Rep. 2022 11 17; 12(1):19805.

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