Malaria, Cerebral

"Malaria, Cerebral" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A condition characterized by somnolence or coma in the presence of an acute infection with PLASMODIUM FALCIPARUM (and rarely other Plasmodium species). Initial clinical manifestations include HEADACHES; SEIZURES; and alterations of mentation followed by a rapid progression to COMA. Pathologic features include cerebral capillaries filled with parasitized erythrocytes and multiple small foci of cortical and subcortical necrosis. (From Adams et al., Principles of Neurology, 6th ed, p136)

Descriptor ID	D016779
MeSH Number(s)	C03.105.300.500 C03.752.530.620 C10.228.228.205.300.500
Concept/Terms	Malaria, Cerebral Malaria, Cerebral Cerebral Malaria Malaria Meningitis Malaria Meningitis Meningitis, Malaria

Below are MeSH descriptors whose meaning is more general than "Malaria, Cerebral".

Diseases [C]
Parasitic Diseases [C03]
Central Nervous System Parasitic Infections [C03.105]
Central Nervous System Protozoal Infections [C03.105.300]
Malaria, Cerebral [C03.105.300.500]
Protozoan Infections [C03.752]
Malaria [C03.752.530]
Malaria, Cerebral [C03.752.530.620]
Nervous System Diseases [C10]
Central Nervous System Diseases [C10.228]
Central Nervous System Infections [C10.228.228]
Central Nervous System Parasitic Infections [C10.228.228.205]
Central Nervous System Protozoal Infections [C10.228.228.205.300]
Malaria, Cerebral [C10.228.228.205.300.500]

Below are MeSH descriptors whose meaning is related to "Malaria, Cerebral".

Below are MeSH descriptors whose meaning is more specific than "Malaria, Cerebral".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Malaria, Cerebral" by people in this website by year, and whether "Malaria, Cerebral" was a major or minor topic of these publications.

Bar chart showing 16 publications over 12 distinct years, with a maximum of 4 publications in 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2011	1	0	1
2013	0	1	1
2014	1	0	1
2015	1	0	1
2016	1	0	1
2018	1	0	1
2019	1	0	1
2020	4	0	4
2022	2	0	2
2023	1	0	1
2024	1	0	1
2025	1	0	1

Below are the most recent publications written about "Malaria, Cerebral" by people in Profiles.

Sobota RS, Stucke EM, Coulibaly D, Lawton JG, Cummings BE, Sebastian S, Dara A, Munro JB, Ouattara A, Kone AK, Kane B, Traor? K, Guindo B, Tangara BM, Niangaly A, Ventimiglia NT, Daou M, Diarra I, Tolo Y, Sissoko M, Maiga F, Diawara A, Traore A, Thera A, Laurens MB, Lyke KE, Kouriba B, Doumbo OK, Plowe CV, Goodlett DR, Silva JC, Thera MA, Travassos MA. A shared inflammatory signature across severe malaria syndromes manifested by transcriptomic, proteomic and metabolomic analyses. Nat Commun. 2025 May 18; 16(1):4620.

View in: PubMed
Silva AF, Torres MDT, Silva LS, Alves FL, Miranda A, Oliveira VX, de la Fuente-Nunez C, Pinheiro AAS. Synthetic angiotensin II peptide derivatives confer protection against cerebral and severe non-cerebral malaria in murine models. Sci Rep. 2024 02 26; 14(1):4682.

View in: PubMed
Alves SAS, Teixeira DE, Peruchetti DB, Silva LS, Brand?o LFP, Caruso-Neves C, Pinheiro AAS. Bradykinin produced during Plasmodium falciparum erythrocytic cycle drives monocyte adhesion to human brain microvascular endothelial cells. Brain Res. 2024 01 01; 1822:148669.

View in: PubMed
Santos ECD, Silva LS, Pinheiro AS, Teixeira DE, Peruchetti DB, Silva-Aguiar RP, Wendt CHC, Miranda KR, Coelho-de-Souza AN, Leal-Cardoso JH, Caruso-Neves C, Pinheiro AAS. The monoterpene 1,8-cineole prevents cerebral edema in a murine model of severe malaria. PLoS One. 2022; 17(5):e0268347.

View in: PubMed
Rodriguez-Mu?oz D, S?nchez ?, P?rez-Benavente S, Contreras-Jurado C, Montero-Pedrazuela A, Toledo-Castillo M, Guti?rrez-Hern?ndez M, Rodrigues-D?ez R, Folgueira C, Briones AM, Sabio G, Monedero-Cobeta I, Chaves-Coira I, Castej?n D, Fern?ndez-Valle E, Regadera J, Bautista JM, Aranda A, Alemany S. Hypothyroidism confers tolerance to cerebral malaria. Sci Adv. 2022 04 08; 8(14):eabj7110.

View in: PubMed
Pontes KAO, Silva LS, Santos EC, Pinheiro AS, Teixeira DE, Peruchetti DB, Silva-Aguiar RP, Wendt CHC, Miranda KR, Coelho-de-Souza AN, Leal-Cardoso JH, Caruso-Neves C, Pinheiro AAS. Eugenol disrupts Plasmodium falciparum intracellular development during the erythrocytic cycle and protects against cerebral malaria. Biochim Biophys Acta Gen Subj. 2021 03; 1865(3):129813.

View in: PubMed
Pereira LMN, Assis PA, de Ara?jo NM, Durso DF, Junqueira C, Ata?de MA, Pereira DB, Lien E, Fitzgerald KA, Zamboni DS, Golenbock DT, Gazzinelli RT. Caspase-8 mediates inflammation and disease in rodent malaria. Nat Commun. 2020 09 14; 11(1):4596.

View in: PubMed
Kaine J, Moran-Guiati J, Tanch J, Clyne B. Cerebral and Plasmodium ovale Malaria in Rhode Island. R I Med J (2013). 2020 Aug 03; 103(6):64-67.

View in: PubMed
Assis PA, Fernandes Durso D, Chacon Cavalcante F, Zaniratto R, Carvalho-Silva AC, Cunha-Neto E, Golenbock DT, Rodrigues Pinto Ferreira L, Tostes Gazzinelli R. Integrative analysis of microRNA and mRNA expression profiles of monocyte-derived dendritic cells differentiation during experimental cerebral malaria. J Leukoc Biol. 2020 10; 108(4):1183-1197.

View in: PubMed
Hirako IC, Assis PA, Galv?o-Filho B, Luster AD, Antonelli LR, Gazzinelli RT. Monocyte-derived dendritic cells in malaria. Curr Opin Microbiol. 2019 12; 52:139-150.

View in: PubMed

People

Explore

Similar Concepts

Top Journals