Epilepsy, Generalized

"Epilepsy, Generalized" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Recurrent conditions characterized by epileptic seizures which arise diffusely and simultaneously from both hemispheres of the brain. Classification is generally based upon motor manifestations of the seizure (e.g., convulsive, nonconvulsive, akinetic, atonic, etc.) or etiology (e.g., idiopathic, cryptogenic, and symptomatic). (From Mayo Clin Proc, 1996 Apr;71(4):405-14)

Descriptor ID	D004829
MeSH Number(s)	C10.228.140.490.375
Concept/Terms	Epilepsy, Generalized Epilepsy, Generalized Epilepsies, Generalized Generalized Epilepsies Generalized Epilepsy Seizure Disorder, Generalized Generalized Seizure Disorder Generalized Seizure Disorders Seizure Disorders, Generalized Epilepsy, Akinetic Epilepsy, Akinetic Akinetic Epilepsies Akinetic Epilepsy Epilepsies, Akinetic Symptomatic Generalized Epilepsy Symptomatic Generalized Epilepsy Epilepsy, Symptomatic Generalized Generalized Epilepsy, Symptomatic Epilepsy, Tonic Epilepsy, Tonic Epilepsies, Tonic Tonic Epilepsies Tonic Epilepsy Generalized Nonconvulsive Seizure Disorder Generalized Nonconvulsive Seizure Disorder Generalized Seizure Disorder, Nonconvulsive Seizure Disorder, Nonconvulsive Generalized Nonconvulsive Seizure Disorder, Generalized Seizure Disorder, Generalized Nonconvulsive Generalized Nonconvulsive Epilepsy Epilepsy, Generalized Nonconvulsive Nonconvulsive Epilepsy, Generalized Nonconvulsive Generalized Seizure Disorder Convulsive Generalized Seizure Disorder Convulsive Generalized Seizure Disorder Generalized Convulsive Epilepsy Convulsive Epilepsies, Generalized Convulsive Epilepsy, Generalized Epilepsies, Generalized Convulsive Epilepsy, Generalized Convulsive Generalized Convulsive Epilepsies Generalized Onset Seizure Disorder Seizure Disorder, Convulsive, Generalized Seizure Disorder, Generalized Onset Seizure Disorder, Generalized, Convulsive Convulsive Seizure Disorder, Generalized Generalized Seizure Disorder, Convulsive Epilepsy, Atonic Epilepsy, Atonic Atonic Epilepsies Atonic Epilepsy Epilepsies, Atonic

Below are MeSH descriptors whose meaning is more general than "Epilepsy, Generalized".

Diseases [C]
Nervous System Diseases [C10]
Central Nervous System Diseases [C10.228]
Brain Diseases [C10.228.140]
Epilepsy [C10.228.140.490]
Epilepsy, Generalized [C10.228.140.490.375]

Below are MeSH descriptors whose meaning is related to "Epilepsy, Generalized".

Below are MeSH descriptors whose meaning is more specific than "Epilepsy, Generalized".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Epilepsy, Generalized" by people in this website by year, and whether "Epilepsy, Generalized" was a major or minor topic of these publications.

Bar chart showing 3 publications over 3 distinct years, with a maximum of 1 publications in 2009 and 2021 and 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2009	0	1	1
2021	1	0	1
2024	0	1	1

Below are the most recent publications written about "Epilepsy, Generalized" by people in Profiles.

Drees C, Afra P, Verner R, Kaye L, Keith A, Jiang M, Szaflarski JP, Nichol K. Feasibility study of microburst VNS therapy in drug-resistant focal and generalized epilepsy. Brain Stimul. 2024 Mar-Apr; 17(2):382-391.

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Ernst ME, Baugh EH, Thomas A, Bier L, Lippa N, Stong N, Mulhern MS, Kushary S, Akman CI, Heinzen EL, Yeh R, Bi W, Hanchard NA, Burrage LC, Leduc MS, Chong JSC, Bend R, Lyons MJ, Lee JA, Suwannarat P, Brilstra E, Simon M, Koopmans M, van Binsbergen E, Groepper D, Fleischer J, Nava C, Keren B, Mignot C, Mathieu S, Mancini GMS, Madan-Khetarpal S, Infante EM, Bluvstein J, Seeley A, Bachman K, Klee EW, Schultz-Rogers LE, Hasadsri L, Barnett S, Ellingson MS, Ferber MJ, Narayanan V, Ramsey K, Rauch A, Joset P, Steindl K, Sheehan T, Poduri A, Vasquez A, Ruivenkamp C, White SM, Pais L, Monaghan KG, Goldstein DB, Sands TT, Aggarwal V. CSNK2B: A broad spectrum of neurodevelopmental disability and epilepsy severity. Epilepsia. 2021 07; 62(7):e103-e109.

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Yu W, Smith AB, Pilitsis JG, Shin DS. Isovaline attenuates generalized epileptiform activity in hippocampal and primary sensory cortices and seizure behavior in pilocarpine treated rats. Neurosci Lett. 2015 Jul 10; 599:125-8.

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Indic P, Narayanan J. Dynamics of frequency flow in epileptic brain during extra-temporal partial and idiopathic generalized epilepsy. Epilepsy Res. 2012 Mar; 99(1-2):176-9.

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Zhao-Shea R, Cohen BN, Just H, McClure-Begley T, Whiteaker P, Grady SR, Salminen O, Gardner PD, Lester HA, Tapper AR. Dopamine D2-receptor activation elicits akinesia, rigidity, catalepsy, and tremor in mice expressing hypersensitive {alpha}4 nicotinic receptors via a cholinergic-dependent mechanism. FASEB J. 2010 Jan; 24(1):49-57.

View in: PubMed

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