"Notochord" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cartilaginous rod of mesodermal cells at the dorsal midline of all CHORDATE embryos. In lower vertebrates, notochord is the backbone of support. In the higher vertebrates, notochord is a transient structure, and segments of the vertebral column will develop around it. Notochord is also a source of midline signals that pattern surrounding tissues including the NEURAL TUBE development.
| Descriptor ID |
D009672
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| MeSH Number(s) |
A16.660
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Notochord".
Below are MeSH descriptors whose meaning is more specific than "Notochord".
This graph shows the total number of publications written about "Notochord" by people in this website by year, and whether "Notochord" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1998 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2013 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Notochord" by people in Profiles.
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Archambault D, Cheong A, Iverson E, Tremblay KD, Mager J. Protein phosphatase 1 regulatory subunit 35 is required for ciliogenesis, notochord morphogenesis, and cell-cycle progression during murine development. Dev Biol. 2020 09 01; 465(1):1-10.
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Golden LD, Small JE. Benign notochordal lesions of the posterior clivus: retrospective review of prevalence and imaging characteristics. J Neuroimaging. 2014 May-Jun; 24(3):245-9.
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Lemons ML, Barua S, Abanto ML, Halfter W, Condic ML. Adaptation of sensory neurons to hyalectin and decorin proteoglycans. J Neurosci. 2005 May 18; 25(20):4964-73.
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Doudney K, Stanier P. Epithelial cell polarity genes are required for neural tube closure. Am J Med Genet C Semin Med Genet. 2005 May 15; 135C(1):42-7.
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Borycki AG, Mendham L, Emerson CP. Control of somite patterning by Sonic hedgehog and its downstream signal response genes. Development. 1998 Feb; 125(4):777-90.
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Pownall ME, Strunk KE, Emerson CP. Notochord signals control the transcriptional cascade of myogenic bHLH genes in somites of quail embryos. Development. 1996 May; 122(5):1475-88.