"YY1 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously expressed zinc finger-containing protein that acts both as a repressor and activator of transcription. It interacts with key regulatory proteins such as TATA-BINDING PROTEIN; TFIIB; and ADENOVIRUS E1A PROTEINS.
Descriptor ID |
D050986
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MeSH Number(s) |
D12.776.260.235.875 D12.776.930.216.875
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Concept/Terms |
YY1 Transcription Factor- YY1 Transcription Factor
- Transcription Factor, YY1
- Yin-Yang-1 Protein
- Yin Yang 1 Protein
- Nuclear Matrix Protein 1
- Delta Transcription Factor
- Transcription Factor, Delta
- NF-D Nuclear Factor
- NF D Nuclear Factor
- Nuclear Factor, NF-D
- Transcriptional Repressor Protein YY1
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Below are MeSH descriptors whose meaning is more general than "YY1 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "YY1 Transcription Factor".
This graph shows the total number of publications written about "YY1 Transcription Factor" by people in this website by year, and whether "YY1 Transcription Factor" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2010 | 1 | 0 | 1 |
2012 | 2 | 0 | 2 |
2013 | 2 | 0 | 2 |
2015 | 1 | 0 | 1 |
2016 | 1 | 0 | 1 |
2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "YY1 Transcription Factor" by people in Profiles.
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Wallingford MC, Hiller J, Zhang K, Mager J. YY1 Is Required for Posttranscriptional Stability of SOX2 and OCT4 Proteins. Cell Reprogram. 2017 08; 19(4):263-269.
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Trabucco SE, Gerstein RM, Zhang H. YY1 Regulates the Germinal Center Reaction by Inhibiting Apoptosis. J Immunol. 2016 09 01; 197(5):1699-707.
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Beketaev I, Zhang Y, Weng KC, Rhee S, Yu W, Liu Y, Mager J, Wang J. cis-Regulatory control of Mesp1 expression by YY1 and SP1 during mouse embryogenesis. Dev Dyn. 2016 Mar; 245(3):379-87.
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Rhee S, Guerrero-Zayas MI, Wallingford MC, Ortiz-Pineda P, Mager J, Tremblay KD. Visceral endoderm expression of Yin-Yang1 (YY1) is required for VEGFA maintenance and yolk sac development. PLoS One. 2013; 8(3):e58828.
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Ramkumar C, Cui H, Kong Y, Jones SN, Gerstein RM, Zhang H. Smurf2 suppresses B-cell proliferation and lymphomagenesis by mediating ubiquitination and degradation of YY1. Nat Commun. 2013; 4:2598.
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Whitfield TW, Wang J, Collins PJ, Partridge EC, Aldred SF, Trinklein ND, Myers RM, Weng Z. Functional analysis of transcription factor binding sites in human promoters. Genome Biol. 2012 Sep 26; 13(9):R50.
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Trask MC, Tremblay KD, Mager J. Yin-Yang1 is required for epithelial-to-mesenchymal transition and regulation of Nodal signaling during mammalian gastrulation. Dev Biol. 2012 Aug 15; 368(2):273-82.
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Griffith GJ, Trask MC, Hiller J, Walentuk M, Pawlak JB, Tremblay KD, Mager J. Yin-yang1 is required in the mammalian oocyte for follicle expansion. Biol Reprod. 2011 Apr; 84(4):654-63.
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Forlani G, Giarda E, Ala U, Di Cunto F, Salani M, Tupler R, Kilstrup-Nielsen C, Landsberger N. The MeCP2/YY1 interaction regulates ANT1 expression at 4q35: novel hints for Rett syndrome pathogenesis. Hum Mol Genet. 2010 Aug 15; 19(16):3114-23.
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McNeil S, Guo B, Stein JL, Lian JB, Bushmeyer S, Seto E, Atchison ML, Penman S, van Wijnen AJ, Stein GS. Targeting of the YY1 transcription factor to the nucleolus and the nuclear matrix in situ: the C-terminus is a principal determinant for nuclear trafficking. J Cell Biochem. 1998 Mar 15; 68(4):500-10.