"Cytochrome P-450 CYP1A1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A liver microsomal cytochrome P-450 monooxygenase capable of biotransforming xenobiotics such as polycyclic hydrocarbons and halogenated aromatic hydrocarbons into carcinogenic or mutagenic compounds. They have been found in mammals and fish. This enzyme, encoded by CYP1A1 gene, can be measured by using ethoxyresorufin as a substrate for the ethoxyresorufin O-deethylase activity.
| Descriptor ID |
D019363
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| MeSH Number(s) |
D08.244.453.005.332 D08.244.453.100.500 D08.811.682.690.708.170.010.277 D08.811.682.690.708.170.020.500 D12.776.422.220.453.010.332 D12.776.422.220.453.100.500
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| Concept/Terms |
Cytochrome P-450 CYP1A1- Cytochrome P-450 CYP1A1
- Cytochrome P 450 CYP1A1
- EROD
- Ethoxyresorufin Dealkylase
- Ethylresorufin O-Deethylase
- CYP1A1 Protein
- 7-Ethoxyresorufin O-Deethylase
- CYP1A1
- Cytochrome P450 IA1
- Ethoxyresorufin O-Deethylase
- CYP 1A1
|
Below are MeSH descriptors whose meaning is more general than "Cytochrome P-450 CYP1A1".
Below are MeSH descriptors whose meaning is more specific than "Cytochrome P-450 CYP1A1".
This graph shows the total number of publications written about "Cytochrome P-450 CYP1A1" by people in this website by year, and whether "Cytochrome P-450 CYP1A1" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Cytochrome P-450 CYP1A1" by people in Profiles.
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Morin SM, Majhi PD, Crisi GM, Gregory KJ, Franca R, Schalet B, Mason H, Casaubon JT, Cao QJ, Haddad S, Makari-Judson G, Jerry DJ, Schneider SS. Interindividual variation contributes to differential PCB 126 induced gene expression in primary breast epithelial cells and tissues. Ecotoxicol Environ Saf. 2022 Aug; 241:113722.
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Wadzinski TL, Geromini K, McKinley Brewer J, Bansal R, Abdelouahab N, Langlois MF, Takser L, Zoeller RT. Endocrine disruption in human placenta: expression of the dioxin-inducible enzyme, CYP1A1, is correlated with that of thyroid hormone-regulated genes. J Clin Endocrinol Metab. 2014 Dec; 99(12):E2735-43.
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Paul KB, Hedge JM, Bansal R, Zoeller RT, Peter R, DeVito MJ, Crofton KM. Developmental triclosan exposure decreases maternal, fetal, and early neonatal thyroxine: a dynamic and kinetic evaluation of a putative mode-of-action. Toxicology. 2012 Oct 09; 300(1-2):31-45.
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Giera S, Bansal R, Ortiz-Toro TM, Taub DG, Zoeller RT. Individual polychlorinated biphenyl (PCB) congeners produce tissue- and gene-specific effects on thyroid hormone signaling during development. Endocrinology. 2011 Jul; 152(7):2909-19.
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Cao J, Patisaul HB, Petersen SL. Aryl hydrocarbon receptor activation in lactotropes and gonadotropes interferes with estradiol-dependent and -independent preprolactin, glycoprotein alpha and luteinizing hormone beta gene expression. Mol Cell Endocrinol. 2011 Feb 20; 333(2):151-9.
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Crandall CJ, Sehl ME, Crawford SL, Gold EB, Habel LA, Butler LM, Sowers MR, Greendale GA, Sinsheimer JS. Sex steroid metabolism polymorphisms and mammographic density in pre- and early perimenopausal women. Breast Cancer Res. 2009; 11(4):R51.
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Gauger KJ, Giera S, Sharlin DS, Bansal R, Iannacone E, Zoeller RT. Polychlorinated biphenyls 105 and 118 form thyroid hormone receptor agonists after cytochrome P4501A1 activation in rat pituitary GH3 cells. Environ Health Perspect. 2007 Nov; 115(11):1623-30.