Endocrine Disruptors

"Endocrine Disruptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Exogenous agents, synthetic and naturally occurring, which are capable of disrupting the functions of the ENDOCRINE SYSTEM including the maintenance of HOMEOSTASIS and the regulation of developmental processes. Endocrine disruptors are compounds that can mimic HORMONES, or enhance or block the binding of hormones to their receptors, or otherwise lead to activating or inhibiting the endocrine signaling pathways and hormone metabolism.

Descriptor ID	D052244
MeSH Number(s)	D27.505.696.353 D27.888.141
Concept/Terms	Endocrine Disruptors Endocrine Disruptors Disruptors, Endocrine Endocrine Disrupting Chemicals Chemicals, Endocrine Disrupting Endocrine Disruptor Effect Endocrine Disruptor Effect Disruptor Effect, Endocrine Effect, Endocrine Disruptor Endocrine Disruptor Effects Disruptor Effects, Endocrine Effects, Endocrine Disruptor

Below are MeSH descriptors whose meaning is more general than "Endocrine Disruptors".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Pharmacologic Actions [D27.505]
Physiological Effects of Drugs [D27.505.696]
Endocrine Disruptors [D27.505.696.353]
Toxic Actions [D27.888]
Endocrine Disruptors [D27.888.141]

Below are MeSH descriptors whose meaning is more specific than "Endocrine Disruptors".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Endocrine Disruptors" by people in this website by year, and whether "Endocrine Disruptors" was a major or minor topic of these publications.

Bar chart showing 72 publications over 19 distinct years, with a maximum of 11 publications in 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2005	1	0	1
2006	2	0	2
2007	2	2	4
2008	1	0	1
2009	3	0	3
2010	2	0	2
2012	2	1	3
2013	4	0	4
2014	6	0	6
2015	8	2	10
2016	11	0	11
2017	4	0	4
2018	4	1	5
2019	4	0	4
2020	4	1	5
2021	2	1	3
2022	1	0	1
2025	1	1	2
2026	0	1	1

Below are the most recent publications written about "Endocrine Disruptors" by people in Profiles.

Mitra PR, Bertrand KA, Pfeiffer RM, Palmer JR, Ramireddy S, Hyer M, Fan S, Strohsnitter WC, Aagaard KM, Huo D, Titus L, Troisi R, Gierach GL. Prenatal diethylstilbestrol exposure and risk of benign breast disease: The National Cancer Institute Diethylstilbestrol Follow-up Study. Int J Cancer. 2026 Jun 15; 158(12):3101-3111.

View in: PubMed
Troisi R, Hatch EE, Bertrand K, Strohsnitter WC, Huo D, Curry M, Hyer M, Palmer JA, Gierach G, Titus L. Sexual behavior and sexual identity in female offspring of women exposed in utero to diethylstilbestrol (DES). J Dev Orig Health Dis. 2025 Nov 10; 16:e41.

View in: PubMed
Carroll JE, Guard HE, March D, Arcaro KF, Huset C, Balasubramanian R, Kontos D, Sturgeon SR. Urinary Levels of Endocrine-Disrupting Chemicals and Breast Density in Young Women. Cancer Epidemiol Biomarkers Prev. 2025 Aug 01; 34(8):1306-1313.

View in: PubMed
Su Y, Santucci-Pereira J, Dang NM, Kanefsky J, Rahulkannan V, Hillegass M, Joshi S, Gurdogan H, Chen Z, Bessonneau V, Rudel R, Ser-Dolansky J, Schneider SS, Russo J. Effects of Pubertal Exposure to Butyl Benzyl Phthalate, Perfluorooctanoic Acid, and Zeranol on Mammary Gland Development and Tumorigenesis in Rats. Int J Mol Sci. 2022 Jan 26; 23(3).

View in: PubMed
Zoeller RT. Endocrine disrupting chemicals and thyroid hormone action. Adv Pharmacol. 2021; 92:401-417.

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Reeves KW, Vieyra G, Grimes NP, Meliker J, Jackson RD, Wactawski-Wende J, Wallace R, Zoeller RT, Bigelow C, Hankinson SE, Manson JE, Cauley JA, Calafat AM. Urinary Phthalate Biomarkers and Bone Mineral Density in Postmenopausal Women. J Clin Endocrinol Metab. 2021 06 16; 106(7):e2567-e2579.

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Mogus JP, LaPlante CD, Bansal R, Matouskova K, Schneider BR, Daniele E, Silva SJ, Hagen MJ, Dunphy KA, Jerry DJ, Schneider SS, Vandenberg LN. Exposure to Propylparaben During Pregnancy and Lactation Induces Long-Term Alterations to the Mammary Gland in Mice. Endocrinology. 2021 06 01; 162(6).

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Gregory KJ, Morin SM, Kubosiak A, Ser-Dolansky J, Schalet BJ, Jerry DJ, Schneider SS. The use of patient-derived breast tissue explants to study macrophage polarization and the effects of environmental chemical exposure. Immunol Cell Biol. 2020 11; 98(10):883-896.

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Heindel JJ, Belcher S, Flaws JA, Prins GS, Ho SM, Mao J, Patisaul HB, Ricke W, Rosenfeld CS, Soto AM, Vom Saal FS, Zoeller RT. Data integration, analysis, and interpretation of eight academic CLARITY-BPA studies. Reprod Toxicol. 2020 12; 98:29-60.

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Vandenberg LN, Prins GS, Patisaul HB, Zoeller RT. The Use and Misuse of Historical Controls in Regulatory Toxicology: Lessons from the CLARITY-BPA Study. Endocrinology. 2020 05 01; 161(5).

View in: PubMed

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