Central Nervous System Depressants

"Central Nervous System Depressants" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A very loosely defined group of drugs that tend to reduce the activity of the central nervous system. The major groups included here are ethyl alcohol, anesthetics, hypnotics and sedatives, narcotics, and tranquilizing agents (antipsychotics and antianxiety agents).

Descriptor ID	D002492
MeSH Number(s)	D27.505.696.277 D27.505.954.427.210
Concept/Terms	Central Nervous System Depressants Central Nervous System Depressants CNS Depressants Depressants, CNS

Below are MeSH descriptors whose meaning is more general than "Central Nervous System Depressants".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Pharmacologic Actions [D27.505]
Physiological Effects of Drugs [D27.505.696]
Central Nervous System Depressants [D27.505.696.277]
Therapeutic Uses [D27.505.954]
Central Nervous System Agents [D27.505.954.427]
Central Nervous System Depressants [D27.505.954.427.210]

Below are MeSH descriptors whose meaning is related to "Central Nervous System Depressants".

Below are MeSH descriptors whose meaning is more specific than "Central Nervous System Depressants".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Central Nervous System Depressants" by people in this website by year, and whether "Central Nervous System Depressants" was a major or minor topic of these publications.

Bar chart showing 32 publications over 14 distinct years, with a maximum of 7 publications in 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	1	0	1
2004	1	0	1
2005	0	1	1
2007	3	1	4
2008	3	4	7
2009	3	1	4
2010	0	3	3
2013	2	0	2
2015	4	0	4
2016	1	0	1
2017	0	1	1
2018	1	0	1
2019	1	0	1
2024	1	0	1

Below are the most recent publications written about "Central Nervous System Depressants" by people in Profiles.

Johnson BE, Borges ES, Gaspari RJ, Galletta GM, Lai JT. Unintentional Ketamine Overdose Via Telehealth. Am J Psychiatry. 2024 Jan 01; 181(1):81-82.

View in: PubMed
Centanni SW, Bedse G, Patel S, Winder DG. Driving the Downward Spiral: Alcohol-Induced Dysregulation of Extended Amygdala Circuits and Negative Affect. Alcohol Clin Exp Res. 2019 10; 43(10):2000-2013.

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Lowe PP, Gyongyosi B, Satishchandran A, Iracheta-Vellve A, Cho Y, Ambade A, Szabo G. Reduced gut microbiome protects from alcohol-induced neuroinflammation and alters intestinal and brain inflammasome expression. J Neuroinflammation. 2018 Oct 27; 15(1):298.

View in: PubMed
Bendinelli C, Ku D, Nebauer S, King KL, Howard T, Gruen R, Evans T, Fitzgerald M, Balogh ZJ. A tale of two cities: prehospital intubation with or without paralysing agents for traumatic brain injury. ANZ J Surg. 2018 May; 88(5):455-459.

View in: PubMed
Lowe PP, Gyongyosi B, Satishchandran A, Iracheta-Vellve A, Ambade A, Kodys K, Catalano D, Ward DV, Szabo G. Alcohol-related changes in the intestinal microbiome influence neutrophil infiltration, inflammation and steatosis in early alcoholic hepatitis in mice. PLoS One. 2017; 12(3):e0174544.

View in: PubMed
Vel?zquez-Marrero C, Burgos A, Garc?a JO, Palacio S, Marrero HG, Bernardo A, P?rez-Laspiur J, Rivera-Oliver M, Seale G, Treistman SN. Alcohol Regulates BK Surface Expression via Wnt/?-Catenin Signaling. J Neurosci. 2016 10 12; 36(41):10625-10639.

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Slater CA, Jackson A, Muldoon PP, Dawson A, O'Brien M, Soll LG, Abdullah R, Carroll FI, Tapper AR, Miles MF, Banks ML, Bettinger JC, Damaj IM. Nicotine Enhances the Hypnotic and Hypothermic Effects of Alcohol in the Mouse. Alcohol Clin Exp Res. 2016 Jan; 40(1):62-72.

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Wills TA, Baucum AJ, Holleran KM, Chen Y, Pasek JG, Delpire E, Tabb DL, Colbran RJ, Winder DG. Chronic intermittent alcohol disrupts the GluN2B-associated proteome and specifically regulates group I mGlu receptor-dependent long-term depression. Addict Biol. 2017 Mar; 22(2):275-290.

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Nascimento NF, Carlson KN, Amaral DN, Logan RW, Seggio JA. Alcohol and lithium have opposing effects on the period and phase of the behavioral free-running activity rhythm. Alcohol. 2015 Jun; 49(4):367-76.

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Silberman Y, Winder DG. Ethanol and corticotropin releasing factor receptor modulation of central amygdala neurocircuitry: An update and future directions. Alcohol. 2015 May; 49(3):179-84.

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