Thyroxine

"Thyroxine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.

Descriptor ID	D013974
MeSH Number(s)	D06.472.931.812 D12.125.072.050.767
Concept/Terms	Thyroxine Thyroxine T4 Thyroid Hormone Thyroid Hormone, T4 Thyroxin O-(4-Hydroxy-3,5-diiodophenyl) 3,5-diiodo-L-tyrosine L-3,5,3',5'-Tetraiodothyronine Levothyroxine L-Thyroxine L Thyroxine 3,5,3',5'-Tetraiodothyronine O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine L-Thyroxin Henning L-Thyroxin Henning L Thyroxin Henning LThyroxin Henning Levothyroxine Sodium Levothyroxine Sodium Sodium Levothyroxine Levoxine Levoxine Levoxyl Levoxyl Lévothyrox Lévothyrox L-Thyroxine Roche L-Thyroxine Roche L Thyroxine Roche Levo-T Levo-T Levo T LevoT Levothroid Levothroid Novothyral Novothyral Berlthyrox Berlthyrox Dexnon Dexnon Novothyrox Novothyrox Oroxine Oroxine Synthroid Synthroid Synthrox Synthrox Thyrax Thyrax Tiroidine Tiroidine Tiroxina Leo Tiroxina Leo Leo, Tiroxina Unithroid Unithroid Eferox Eferox Eltroxin Eltroxin Thevier Eltroxine Eltroxine Euthyrox Euthyrox Eutirox L-Thyrox L-Thyrox L Thyrox L-Thyroxin beta L-Thyroxin beta L Thyroxin beta LThyroxin beta Levothyroid Levothyroid Levothyroxin Deladande Levothyroxin Deladande Deladande, Levothyroxin Levothyroxin Delalande Delalande, Levothyroxin

Below are MeSH descriptors whose meaning is more general than "Thyroxine".

Chemicals and Drugs [D]
Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
Hormones [D06.472]
Thyroid Hormones [D06.472.931]
Thyroxine [D06.472.931.812]
Amino Acids, Peptides, and Proteins [D12]
Amino Acids [D12.125]
Amino Acids, Cyclic [D12.125.072]
Amino Acids, Aromatic [D12.125.072.050]
Thyroxine [D12.125.072.050.767]

Below are MeSH descriptors whose meaning is related to "Thyroxine".

Below are MeSH descriptors whose meaning is more specific than "Thyroxine".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Thyroxine" by people in this website by year, and whether "Thyroxine" was a major or minor topic of these publications.

Bar chart showing 33 publications over 18 distinct years, with a maximum of 4 publications in 2004 and 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
2000	1	2	3
2001	0	1	1
2003	1	0	1
2004	3	1	4
2007	0	2	2
2008	1	0	1
2009	1	1	2
2010	0	1	1
2011	0	1	1
2012	1	0	1
2013	2	0	2
2014	1	1	2
2017	2	2	4
2018	2	0	2
2019	1	1	2
2021	0	2	2
2023	0	1	1

Below are the most recent publications written about "Thyroxine" by people in Profiles.

Feldman PM, Rodriguez N, Morrison E, Barton B, Lee MM. Prospective study of thyroid function in the first year of life in infants with Down syndrome. Eur J Pediatr. 2023 Jun; 182(6):2903-2911.

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Zoeller RT. Endocrine disrupting chemicals and thyroid hormone action. Adv Pharmacol. 2021; 92:401-417.

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Mardhiyah D, Komaruddin WN, Jalal FN, Wuryanti S, Bahri S, Qomariah Q, Sosiawan I, Marsiati H, Legiono L, Hanif H, Woskie S, Kongtip P. Comparison of Thyroid Hormone Levels between Women Farmers and Non-Farmers in Banten Indonesia. Int J Environ Res Public Health. 2021 06 19; 18(12).

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Kongtip P, Nankongnab N, Kallayanatham N, Pundee R, Choochouy N, Yimsabai J, Woskie S. Thyroid Hormones in Conventional and Organic Farmers in Thailand. Int J Environ Res Public Health. 2019 07 29; 16(15).

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Ellervik C, Roselli C, Christophersen IE, Alonso A, Pietzner M, Sitlani CM, Trompet S, Arking DE, Geelhoed B, Guo X, Kleber ME, Lin HJ, Lin H, MacFarlane P, Selvin E, Shaffer C, Smith AV, Verweij N, Weiss S, Cappola AR, D?rr M, Gudnason V, Heckbert S, Mooijaart S, M?rz W, Psaty BM, Ridker PM, Roden D, Stott DJ, V?lzke H, Benjamin EJ, Delgado G, Ellinor P, Homuth G, K?ttgen A, Jukema JW, Lubitz SA, Mora S, Rienstra M, Rotter JI, Shoemaker MB, Sotoodehnia N, Taylor KD, van der Harst P, Albert CM, Chasman DI. Assessment of the Relationship Between Genetic Determinants of Thyroid Function and Atrial Fibrillation: A Mendelian Randomization Study. JAMA Cardiol. 2019 02 01; 4(2):144-152.

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Chang TC, Chin YT, Nana AW, Wang SH, Liao YM, Chen YR, Shih YJ, Changou CA, Yang YS, Wang K, Whang-Peng J, Wang LS, Stain SC, Shih A, Lin HY, Wu CH, Davis PJ. Enhancement by Nano-Diamino-Tetrac of Antiproliferative Action of Gefitinib on Colorectal Cancer Cells: Mediation by EGFR Sialylation and PI3K Activation. Horm Cancer. 2018 12; 9(6):420-432.

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Aldasouqi SA, Quickel MA, Silevany FF, Jamal I. LETTER TO THE EDITOR. Endocr Pract. 2018 Mar; 24(3):315-316.

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Marimuthu SP, Iyer G, Segal JB, Singh S. Patient-relevant outcomes associated with generic tamsulosin, levothyroxine and amphetamine in the FDA Adverse Event Reporting System: a pilot study. J Comp Eff Res. 2017 Jul; 6(5):437-447.

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Creo AL, Candela N, Lee MM, Feldman PM. An Unusual Manifestation of Celiac Disease in an Adolescent With Down Syndrome and Graves Disease. J Pediatr Gastroenterol Nutr. 2017 07; 65(1):e20-e22.

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Villanger GD, Learner E, Longnecker MP, Ask H, Aase H, Zoeller RT, Knudsen GP, Reichborn-Kjennerud T, Zeiner P, Engel SM. Effects of Sample Handling and Analytical Procedures on Thyroid Hormone Concentrations in Pregnant Women's Plasma. Epidemiology. 2017 05; 28(3):365-369.

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