Mannose-Binding Lectin

"Mannose-Binding Lectin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A specific mannose-binding member of the collectin family of lectins. It binds to carbohydrate groups on invading pathogens and plays a key role in the MANNOSE-BINDING LECTIN COMPLEMENT PATHWAY.

Descriptor ID	D037601
MeSH Number(s)	D12.776.503.280.249.500 D12.776.503.311.500
Concept/Terms	Mannose-Binding Lectin Mannose-Binding Lectin Lectin, Mannose-Binding Mannose Binding Lectin Mannose-Binding Protein Mannose Binding Protein Mannan-Binding Protein Mannan Binding Protein Mannan-Binding Lectin Lectin, Mannan-Binding Mannan Binding Lectin

Below are MeSH descriptors whose meaning is more general than "Mannose-Binding Lectin".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Lectins [D12.776.503]
Lectins, C-Type [D12.776.503.280]
Collectins [D12.776.503.280.249]
Mannose-Binding Lectin [D12.776.503.280.249.500]
Mannose-Binding Lectins [D12.776.503.311]
Mannose-Binding Lectin [D12.776.503.311.500]

Below are MeSH descriptors whose meaning is related to "Mannose-Binding Lectin".

Below are MeSH descriptors whose meaning is more specific than "Mannose-Binding Lectin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Mannose-Binding Lectin" by people in this website by year, and whether "Mannose-Binding Lectin" was a major or minor topic of these publications.

Bar chart showing 10 publications over 7 distinct years, with a maximum of 3 publications in 2004

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2004	3	0	3
2005	1	0	1
2007	1	0	1
2009	2	0	2
2010	1	0	1
2012	1	0	1

Below are the most recent publications written about "Mannose-Binding Lectin" by people in Profiles.

Takahashi K, Kurokawa K, Moyo P, Jung DJ, An JH, Chigweshe L, Paul E, Lee BL. Intradermal immunization with wall teichoic acid (WTA) elicits and augments an anti-WTA IgG response that protects mice from methicillin-resistant Staphylococcus aureus infection independent of mannose-binding lectin status. PLoS One. 2013; 8(8):e69739.

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Albert RK, Connett J, Curtis JL, Martinez FJ, Han MK, Lazarus SC, Woodruff PG. Mannose-binding lectin deficiency and acute exacerbations of chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis. 2012; 7:767-77.

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Zhou Y, Lu K, Pfefferle S, Bertram S, Glowacka I, Drosten C, P?hlmann S, Simmons G. A single asparagine-linked glycosylation site of the severe acute respiratory syndrome coronavirus spike glycoprotein facilitates inhibition by mannose-binding lectin through multiple mechanisms. J Virol. 2010 Sep; 84(17):8753-64.

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Ruseva M, Kolev M, Dagnaes-Hansen F, Hansen SB, Takahashi K, Ezekowitz A, Thiel S, Jensenius JC, Gadjeva M. Mannan-binding lectin deficiency modulates the humoral immune response dependent on the genetic environment. Immunology. 2009 Jun; 127(2):279-88.

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Thiel S, Gadjeva M. Humoral pattern recognition molecules: mannan-binding lectin and ficolins. Adv Exp Med Biol. 2009; 653:58-73.

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Marzi A, Mitchell DA, Chaipan C, Fisch T, Doms RW, Carrington M, Desrosiers RC, P?hlmann S. Modulation of HIV and SIV neutralization sensitivity by DC-SIGN and mannose-binding lectin. Virology. 2007 Nov 25; 368(2):322-30.

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?stergaard J, Thiel S, Gadjeva M, Hansen TK, Rasch R, Flyvbjerg A. Mannose-binding lectin deficiency attenuates renal changes in a streptozotocin-induced model of type 1 diabetes in mice. Diabetologia. 2007 Jul; 50(7):1541-9.

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Van Patten SM, Hughes H, Huff MR, Piepenhagen PA, Waire J, Qiu H, Ganesa C, Reczek D, Ward PV, Kutzko JP, Edmunds T. Effect of mannose chain length on targeting of glucocerebrosidase for enzyme replacement therapy of Gaucher disease. Glycobiology. 2007 May; 17(5):467-78.

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M?ller-Kristensen M, Wang W, Ruseva M, Thiel S, Nielsen S, Takahashi K, Shi L, Ezekowitz A, Jensenius JC, Gadjeva M. Mannan-binding lectin recognizes structures on ischaemic reperfused mouse kidneys and is implicated in tissue injury. Scand J Immunol. 2005 May; 61(5):426-34.

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Gadjeva M, Paludan SR, Thiel S, Slavov V, Ruseva M, Eriksson K, L?whagen GB, Shi L, Takahashi K, Ezekowitz A, Jensenius JC. Mannan-binding lectin modulates the response to HSV-2 infection. Clin Exp Immunol. 2004 Nov; 138(2):304-11.

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