Hyper-IgM Immunodeficiency Syndrome
                             
                            
                            
                                
                            
                            
                                
                            
                            
                            
                                
                                    
                                            
	"Hyper-IgM Immunodeficiency Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				A rare inherited immunodeficiency syndrome characterized by normal or elevated serum IMMUNOGLOBULIN M levels with absence of IMMUNOGLOBULIN G; IMMUNOGLOBULIN A; and IMMUNOGLOBULIN E. It results in a profound susceptibility to BACTERIAL INFECTIONS and an increased susceptibility to OPPORTUNISTIC INFECTIONS. Several subtypes of hyper-IgM immunodeficiency syndrome exist depending upon the location of genetic mutation.
    
			
			
				
				
					
						| Descriptor ID | 
										
							D053306
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						| MeSH Number(s) | 
						
							 C15.378.147.333.249 C16.320.413 C20.673.430.249 
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						| Concept/Terms | 
						
							Hyper-IgM Immunodeficiency Syndrome- Hyper-IgM Immunodeficiency Syndrome
 - Hyper IgM Immunodeficiency Syndrome
 - Hyper-IgM Immunodeficiency Syndromes
 - Immunodeficiency Syndrome, Hyper-IgM
 - Immunodeficiency Syndromes, Hyper-IgM
 - Syndrome, Hyper-IgM Immunodeficiency
 - Syndromes, Hyper-IgM Immunodeficiency
 - Immunodeficiency with Hyper-IgM Syndrome
 - Immunodeficiency with Hyper IgM Syndrome
 - Hyper-IgM Syndrome
 - Hyper IgM Syndrome
 - Hyper-IgM Syndromes
 
  Hyper-IgM Immunodeficiency Syndrome, Type 5- Hyper-IgM Immunodeficiency Syndrome, Type 5
 - Hyper IgM Immunodeficiency Syndrome, Type 5
 - Hyper-IgM Immunodeficiency Syndrome Type 5
 - Hyper IgM Immunodeficiency Syndrome Type 5
 - Immunodeficiency with Hyper-IgM, Type 5
 - Immunodeficiency with Hyper IgM, Type 5
 - HIGM5 Syndrome
 - HIGM5 Syndromes
 - Hyper-IgM Syndrome 5
 - Hyper IgM Syndrome 5
 - Hyper-IgM Syndrome 5s
 
  Hyper-IgM Immunodeficiency Syndrome, Type 2- Hyper-IgM Immunodeficiency Syndrome, Type 2
 - Hyper IgM Immunodeficiency Syndrome, Type 2
 - Hyper-IgM Syndrome 2
 - Hyper IgM Syndrome 2
 - HIGM2 Syndrome
 - HIGM2 Syndromes
 - Hyper-IgM Immunodeficiency Syndrome Type 2
 - Hyper IgM Immunodeficiency Syndrome Type 2
 - Immunodeficiency with Hyper-IgM, Type 2
 - Immunodeficiency with Hyper IgM, Type 2
 
  Hyper-IgM Immunodeficiency Syndrome, Type 3- Hyper-IgM Immunodeficiency Syndrome, Type 3
 - Hyper IgM Immunodeficiency Syndrome, Type 3
 - Immunodeficiency with Hyper-IgM, Type 3
 - Immunodeficiency with Hyper IgM, Type 3
 - Hyper-IgM Syndrome 3
 - Hyper IgM Syndrome 3
 - HIGM3 Syndrome
 - HIGM3 Syndromes
 - Hyper-IgM Immunodeficiency Syndrome Type 3
 - Hyper IgM Immunodeficiency Syndrome Type 3
 
  
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				Below are MeSH descriptors whose meaning is more general than "Hyper-IgM Immunodeficiency Syndrome".
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "Hyper-IgM Immunodeficiency Syndrome".
				
			 
		 
	 
 
                                        
                                            
	
	
		
			
			
					
				This graph shows the total number of publications written about "Hyper-IgM Immunodeficiency Syndrome" by people in this website by year, and whether "Hyper-IgM Immunodeficiency Syndrome" was a major or minor topic of these publications. 
				
					
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				Below are the most recent publications written about "Hyper-IgM Immunodeficiency Syndrome" by people in Profiles.
						
					
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Rizvi M, Pathak D, Freedman JE, Chakrabarti S. CD40-CD40 ligand interactions in oxidative stress, inflammation and vascular disease. Trends Mol Med. 2008 Dec; 14(12):530-8.