A familial, cerebral arteriopathy mapped to chromosome 19q12, and characterized by the presence of granular deposits in small CEREBRAL ARTERIES producing ischemic STROKE; PSEUDOBULBAR PALSY; and multiple subcortical infarcts (CEREBRAL INFARCTION). CADASIL is an acronym for Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy. CADASIL differs from BINSWANGER DISEASE by the presence of MIGRAINE WITH AURA and usually by the lack of history of arterial HYPERTENSION. (From Bradley et al, Neurology in Clinical Practice, 2000, p1146)

Descriptor ID	D046589
MeSH Number(s)	C10.228.140.300.275.249 C10.228.140.300.400.203 C10.228.140.300.510.200.175 C10.228.140.380.230.124 C14.907.253.329.249 C14.907.253.560.200.175 C16.320.129
Concept/Terms	CADASIL CADASIL Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy Dementia, Hereditary Multi-Infarct Type Dementia, Hereditary Multi Infarct Type Cerebral Arteriopathy with Subcortical Infarcts and Leukoencephalopathy CADASILM CADASILM

Below are MeSH descriptors whose meaning is more general than "CADASIL".

Below are MeSH descriptors whose meaning is related to "CADASIL".

Below are MeSH descriptors whose meaning is more specific than "CADASIL".