"CADASIL" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A familial, cerebral arteriopathy mapped to chromosome 19q12, and characterized by the presence of granular deposits in small CEREBRAL ARTERIES producing ischemic STROKE; PSEUDOBULBAR PALSY; and multiple subcortical infarcts (CEREBRAL INFARCTION). CADASIL is an acronym for Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy. CADASIL differs from BINSWANGER DISEASE by the presence of MIGRAINE WITH AURA and usually by the lack of history of arterial HYPERTENSION. (From Bradley et al, Neurology in Clinical Practice, 2000, p1146)
Descriptor ID |
D046589
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MeSH Number(s) |
C10.228.140.300.275.249 C10.228.140.300.400.203 C10.228.140.300.510.200.175 C10.228.140.380.230.124 C14.907.253.329.249 C14.907.253.560.200.175 C16.320.129
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Concept/Terms |
CADASIL- CADASIL
- Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy
- Dementia, Hereditary Multi-Infarct Type
- Dementia, Hereditary Multi Infarct Type
- Cerebral Arteriopathy with Subcortical Infarcts and Leukoencephalopathy
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Below are MeSH descriptors whose meaning is more general than "CADASIL".
Below are MeSH descriptors whose meaning is more specific than "CADASIL".
This graph shows the total number of publications written about "CADASIL" by people in this website by year, and whether "CADASIL" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2017 | 1 | 0 | 1 |
2019 | 0 | 1 | 1 |
2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "CADASIL" by people in Profiles.
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Riordan CP, Lyon HN, McIntyre JK. Craniosynostosis of the Metopic Suture in a Patient With CADASIL/Lehman Syndrome. J Craniofac Surg. 2021 Nov-Dec 01; 32(8):e737-e739.
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Henninger N, Mayasi Y. Nucleic Acid Therapies for Ischemic Stroke. Neurotherapeutics. 2019 04; 16(2):299-313.
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Bouley AJ, Yaghi S. CADASIL as a Multiple Sclerosis Mimic. R I Med J (2013). 2017 Nov 01; 100(11):37-38.
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Rushia SN, Garcon E, Sneed JR. The Implications of CADASIL as a Genetic Model of Vascular Depression. Am J Geriatr Psychiatry. 2017 07; 25(7):728-729.