Adenomatous Polyposis Coli

"Adenomatous Polyposis Coli" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood.

Descriptor ID	D011125
MeSH Number(s)	C04.557.470.035.215.100 C04.588.274.476.411.307.089 C04.700.100 C06.301.371.411.307.090 C06.405.249.411.307.090 C06.405.469.158.356.090 C06.405.469.491.307.090 C06.405.469.578.249 C16.320.700.100
Concept/Terms	Adenomatous Polyposis Coli Adenomatous Polyposis Coli Adenomatous Polyposis Colus Coli, Adenomatous Polyposis Colus, Adenomatous Polyposis Polyposis Coli, Adenomatous Polyposis Colus, Adenomatous Polyposis Syndrome, Familial Familial Polyposis Syndromes Familial Adenomatous Polyposis Coli Adenomatous Polyposis Coli, Familial Adenomatous Polyposis of the Colon Familial Adenomatous Polyposis Adenomatous Polyposes, Familial Adenomatous Polyposis, Familial Familial Adenomatous Polyposes Polyposes, Familial Adenomatous Polyposis, Familial Adenomatous Familial Polyposis Coli Familial Adenomatous Polyposis of the Colon Familial Multiple Polyposi Familial Multiple Polyposus Multiple Polyposi, Familial Multiple Polyposus, Familial Polyposi, Familial Multiple Polyposus, Familial Multiple Familial Polyposis of the Colon Hereditary Polyposis Coli Coli, Hereditary Polyposis Colus, Hereditary Polyposis Hereditary Polyposis Colus Polyposis Coli, Hereditary Polyposis Colus, Hereditary Familial Multiple Polyposis Familial Multiple Polyposes Multiple Polyposes, Familial Multiple Polyposis, Familial Polyposes, Familial Multiple Polyposis, Familial Multiple Familial Multiple Polyposis Syndrome Familial Polyposis Syndrome Myh-Associated Polyposis Myh Associated Polyposis Myh-Associated Polyposes Polyposes, Myh-Associated Polyposis, Myh-Associated Polyposis Coli Coli, Polyposis Colus, Polyposis Polyposis Colus Polyposis Coli, Familial Coli, Familial Polyposis Colus, Familial Polyposis Familial Polyposis Colus Polyposis Colus, Familial Familial Intestinal Polyposis Familial Intestinal Polyposis Familial Intestinal Polyposes Intestinal Polyposes, Familial Intestinal Polyposis, Familial Polyposis, Adenomatous Intestinal Polyposis, Adenomatous Intestinal Adenomatous Intestinal Polyposes Adenomatous Intestinal Polyposis Intestinal Polyposis, Adenomatous

Below are MeSH descriptors whose meaning is more general than "Adenomatous Polyposis Coli".

Diseases [C]
Neoplasms [C04]
Neoplasms by Histologic Type [C04.557]
Neoplasms, Glandular and Epithelial [C04.557.470]
Adenoma [C04.557.470.035]
Adenomatous Polyps [C04.557.470.035.215]
Adenomatous Polyposis Coli [C04.557.470.035.215.100]
Neoplasms by Site [C04.588]
Digestive System Neoplasms [C04.588.274]
Gastrointestinal Neoplasms [C04.588.274.476]
Intestinal Neoplasms [C04.588.274.476.411]
Colorectal Neoplasms [C04.588.274.476.411.307]
Adenomatous Polyposis Coli [C04.588.274.476.411.307.089]
Neoplastic Syndromes, Hereditary [C04.700]
Adenomatous Polyposis Coli [C04.700.100]
Digestive System Diseases [C06]
Digestive System Neoplasms [C06.301]
Gastrointestinal Neoplasms [C06.301.371]
Intestinal Neoplasms [C06.301.371.411]
Colorectal Neoplasms [C06.301.371.411.307]
Adenomatous Polyposis Coli [C06.301.371.411.307.090]
Gastrointestinal Diseases [C06.405]
Gastrointestinal Neoplasms [C06.405.249]
Intestinal Neoplasms [C06.405.249.411]
Colorectal Neoplasms [C06.405.249.411.307]
Adenomatous Polyposis Coli [C06.405.249.411.307.090]
Intestinal Diseases [C06.405.469]
Colonic Diseases [C06.405.469.158]
Colorectal Neoplasms [C06.405.469.158.356]
Adenomatous Polyposis Coli [C06.405.469.158.356.090]
Intestinal Neoplasms [C06.405.469.491]
Colorectal Neoplasms [C06.405.469.491.307]
Adenomatous Polyposis Coli [C06.405.469.491.307.090]
Intestinal Polyposis [C06.405.469.578]
Adenomatous Polyposis Coli [C06.405.469.578.249]
Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
Genetic Diseases, Inborn [C16.320]
Neoplastic Syndromes, Hereditary [C16.320.700]
Adenomatous Polyposis Coli [C16.320.700.100]

Below are MeSH descriptors whose meaning is more specific than "Adenomatous Polyposis Coli".

Adenomatous Polyposis Coli
Gardner Syndrome

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Adenomatous Polyposis Coli" by people in this website by year, and whether "Adenomatous Polyposis Coli" was a major or minor topic of these publications.

Bar chart showing 6 publications over 5 distinct years, with a maximum of 2 publications in 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2003	0	1	1
2008	2	0	2
2010	1	0	1
2014	0	1	1
2025	1	0	1

Below are the most recent publications written about "Adenomatous Polyposis Coli" by people in Profiles.

Widdowson KR, Chung S, Yang M, Lindberg JM. Hepatoid carcinoma of the pancreas in a patient with familial adenomatous polyposis. BMJ Case Rep. 2025 Jun 12; 18(6).

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Gupta RK, Ali S, Sakhuja P, Mukherjee D, Agarwal AK, Puri AS. Colorectal carcinoma up to the second decade of life: An 8-year experience in a tertiary care center. Indian J Cancer. 2014 Oct-Dec; 51(4):557-9.

View in: PubMed
Swietlicki EA, Bala S, Lu J, Shaker A, Kularatna G, Levin MS, Rubin DC. Epimorphin deletion inhibits polyposis in the Apcmin/+ mouse model of colon carcinogenesis via decreased myofibroblast HGF secretion. Am J Physiol Gastrointest Liver Physiol. 2013 Oct 15; 305(8):G564-72.

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Zella GC, Hait EJ, Glavan T, Gevers D, Ward DV, Kitts CL, Korzenik JR. Distinct microbiome in pouchitis compared to healthy pouches in ulcerative colitis and familial adenomatous polyposis. Inflamm Bowel Dis. 2011 May; 17(5):1092-100.

View in: PubMed
Yeung AT, Patel BB, Li XM, Seeholzer SH, Coudry RA, Cooper HS, Bellacosa A, Boman BM, Zhang T, Litwin S, Ross EA, Conrad P, Crowell JA, Kopelovich L, Knudson A. One-hit effects in cancer: altered proteome of morphologically normal colon crypts in familial adenomatous polyposis. Cancer Res. 2008 Sep 15; 68(18):7579-86.

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Gounaris E, Tung CH, Restaino C, Maehr R, Kohler R, Joyce JA, Ploegh HL, Plough HL, Barrett TA, Weissleder R, Khazaie K. Live imaging of cysteine-cathepsin activity reveals dynamics of focal inflammation, angiogenesis, and polyp growth. PLoS One. 2008 Aug 13; 3(8):e2916.

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Herline AJ, Meisinger LL, Rusin LC, Roberts PL, Murray JJ, Coller JA, Marcello PW, Schoetz DJ. Is routine pouch surveillance for dysplasia indicated for ileoanal pouches? Dis Colon Rectum. 2003 Feb; 46(2):156-9.

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Hughes SA, Carothers AM, Hunt DH, Moran AE, Mueller JD, Bertagnolli MM. Adenomatous polyposis coli truncation alters cytoskeletal structure and microtubule stability in early intestinal tumorigenesis. J Gastrointest Surg. 2002 Nov-Dec; 6(6):868-74; discussion 875.

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Li FP, Thurber WA, Seddon J, Holmes GE. Hepatoblastoma in families with polyposis coli. JAMA. 1987 May 08; 257(18):2475-7.

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